Vascular smooth muscle contraction in hypertension [PDF]
Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia and chronic kidney disease.
Alves-Lopes, Rheure+6 more
core +1 more source
Identification of a rhythmic firing pattern in the enteric nervous system that generates rhythmic electrical activity in smooth muscle [PDF]
The enteric nervous system (ENS) contains millions of neurons essential for organization of motor behavior of the intestine. It is well established that the large intestine requires ENS activity to drive propulsive motor behaviors.
Brookes, Simon J+10 more
core +2 more sources
Phosphorylation of Subunit Proteins of Intermediate Filaments from Chicken Muscle and Nonmuscle Cells [PDF]
The phosphorylation of the subunit proteins of intermediate (10-nm) filaments has been investigated in chicken muscle and nonmuscle cells by using a two-dimensional gel electrophoresis system. Desmin, the 50,000-dalton subunit protein of the intermediate
Balzer, David R., Jr.+2 more
core +1 more source
Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone. [PDF]
The present study focused on the role of microRNA-139-5p (miRNA-139-5p) in the regulation of basal tone in internal anal sphincter (IAS). Applying genome-wide miRNA microarrays on the phenotypically distinct smooth muscle cells (SMCs) within the rat ...
Addya, Sankar+7 more
core +2 more sources
Mechanisms of vascular smooth muscle contraction and the basis for pharmacologic treatment of smooth muscle disorders [PDF]
The smooth muscle cell directly drives the contraction of the vascular wall and hence regulates the size of the blood vessel lumen. We review here the current understanding of the molecular mechanisms by which agonists, therapeutics, and diseases ...
Aggarwal, M.+5 more
core +1 more source
Alteration of cystic airway mesenchyme in congenital pulmonary airway malformation. [PDF]
Congenital pulmonary airway malformation (CPAM) is the most common congenital lesion detected in the neonatal lung, which may lead to respiratory distress, infection, and pneumothorax.
Jiang, Yi+9 more
core +3 more sources
Herbal extracts modulate the amplitude and frequency of slow waves in circular smooth muscle of mouse small intestine [PDF]
Background: Herbal preparations like STW 5 (Iberogast(R)) are widely used drugs in the treatment of dyspepsia and motility-related disorders of the gastrointestinal tract.
Allescher, H. D.+6 more
core +1 more source
Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell [PDF]
This work aimed to establish the lineage of cells similar to the interstitial cells of Cajal (ICC), the arterial ICC-like (AIL) cells, which have recently been described in resistance arteries, and to study their location in the artery wall.
Bolton, TB+5 more
core +3 more sources
Interest in the functions of intracellular chloride expanded about twenty years ago but mostly this referred to tissues other than smooth muscle. On the other hand, accumulation of chloride above equilibrium seems to have been recognised more readily in smooth muscle.
A.R. Chipperfield, A.A. Harper
openaire +3 more sources
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source