HDAC4 regulates skeletal muscle regeneration via soluble factors [PDF]
, 2018 Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini +5 more
core +3 more sources
Fusion-Independent Satellite Cell Communication to Muscle Fibers During Load-Induced Hypertrophy
Function, 2020 The “canonical” function of Pax7+ muscle stem cells (satellite cells) during hypertrophic growth of adult muscle fibers is myonuclear donation via fusion to support increased transcriptional output.
Kevin A Murach +11 more
doaj +1 more source
The action of obestatin in skeletal muscle repair: stem cell expansion, muscle growth, and microenvironment remodeling [PDF]
, 2015 The development of therapeutic strategies for skeletal muscle diseases, such as physical injuries and myopathies, depends on the knowledge of regulatory signals that control the myogenic process. The obestatin/GPR39 system operates as an autocrine signal
ADAMO, Sergio +16 more
core +1 more source
HSP70 drives myoblast fusion during C2C12 myogenic differentiation
Biology Open, 2020 In response to injury, skeletal muscle stem cells (MuSCs) undergo myogenesis where they become activated, proliferate rapidly, differentiate and undergo fusion to form multinucleated myotubes. Dramatic changes in cell size, shape, metabolism and motility
Savant S. Thakur +7 more
doaj +1 more source
Skeletal Muscle, 2022 Background Aging decreases skeletal muscle mass and quality. Maintenance of healthy muscle is regulated by a balance between protein and organellar synthesis and their degradation.
Matthew Triolo +3 more
doaj +1 more source
Microtubules orchestrate local translation to enable cardiac growth
Nature Communications, 2021 New contractile units are required during cardiac hypertrophy, though it remains unclear precisely where and how these new sarcomeres are added. Here the authors reveal that in the heart, microtubules spatiotemporally regulate mRNAs and ribosomes to ...
Emily A. Scarborough +8 more
doaj +1 more source
Changes of smooth muscle contractile filaments in small bowel atresia [PDF]
, 2012 AIM: To investigate morphological changes of intestinal smooth muscle contractile fibres in small bowel atresia patients. METHODS: Resected small bowel specimens from small bowel atresia patients (n = 12) were divided into three sections (proximal ...
Fiegel, Henning C. +4 more
core +1 more source
Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue [PDF]
, 2020 Statin-related muscle side effects are a constant healthcare problem since patient compliance is dependent on side effects. Statins reduce plasma cholesterol levels and can prevent secondary cardiovascular diseases.
Dittmar, Gunnar +10 more
core +1 more source
Trends in concentrations of atmospheric gaseous and particulate species in rural eastern Tennessee as related to primary emission reductions [PDF]
Atmospheric Chemistry and Physics, 2015 Air quality measurements at Look Rock, Tennessee – on the western edge of the Great Smoky Mountains National Park – were begun in 1980 and expanded during the 1980s to a National Park Service (NPS) IMPROVE network station.
R. L. Tanner +2 more
doaj +1 more source
The bile duct ligated rat : a relevant model to study muscle mass loss in cirrhosis [PDF]
, 2016 Muscle mass loss and hepatic encephalopathy (complex neuropsychiatric disorder) are serious complications of chronic liver disease (cirrhosis) which impact negatively on clinical outcome and quality of life and increase mortality.
Bosoi, Cristina R. +7 more
core +1 more source