Results 31 to 40 of about 3,759,300 (312)

Muscle Contraction [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2018
Muscle cells are designed to generate force and movement. There are three types of mammalian muscles-skeletal, cardiac, and smooth. Skeletal muscles are attached to bones and move them relative to each other. Cardiac muscle comprises the heart, which pumps blood through the vasculature.
H Lee, Sweeney, David W, Hammers
openaire   +2 more sources

Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice

open access: yesScientific Reports, 2019
Duchenne muscular dystrophy (DMD) is an X-linked genetic disease characterized by progressive muscle wasting and weakness and premature death. Glucocorticoids (e.g.
Daniel J. Ham   +9 more
doaj   +1 more source

Distinct mechanisms involving diacylglycerol, ceramides, and inflammation underlie insulin resistance in oxidative and glycolytic muscles from high fat-fed rats

open access: yesScientific Reports, 2021
This study investigated whether oxidative and glycolytic rat skeletal muscles respond differently to a high-fat (HF) sucrose-enriched diet with respect to diacylglycerol (DAG) and ceramides accumulation, protein kinase C (PKC) activation, glucose ...
Shailee Jani   +6 more
doaj   +1 more source

Role of physiological ClC-1 Cl- ion channel regulation for the excitability and function of working skeletal muscle. [PDF]

open access: yes, 2016
Electrical membrane properties of skeletal muscle fibers have been thoroughly studied over the last five to six decades. This has shown that muscle fibers from a wide range of species, including fish, amphibians, reptiles, birds, and mammals, are all ...
Chen, Tsung-Yu   +4 more
core   +1 more source

The coagulation of myosin in muscle [PDF]

open access: yes, 1937
The coagulation of myosin is one of the few changes in the proteins of muscle known to take place during contraction and rigor. Although under certain conditions as much as one-third of the total protein of muscle may become insoluble, the significance ...
Mirsky, A. E.
core   +2 more sources

Myocardial Dysfunction in an Animal Model of Cancer Cachexia [PDF]

open access: yes, 2011
Aims Fatigue is a common occurrence in cancer patients regardless of tumor type or anti-tumor therapies and is an especially problematic symptom in persons with incurable tumor disease.
Crawford, Danielle   +7 more
core   +2 more sources

Muscle-Specific Cellular and Molecular Adaptations to Late-Life Voluntary Concurrent Exercise

open access: yesFunction, 2022
Murine exercise models can provide information on factors that influence muscle adaptability with aging, but few translatable solutions exist. Progressive weighted wheel running (PoWeR) is a simple, voluntary, low-cost, high-volume endurance/resistance ...
Cory M Dungan   +12 more
doaj   +1 more source

Muscle Development: Making Drosophila muscle [PDF]

open access: yesCurrent Biology, 1995
Analysis of flies with mutations in the gene encoding the D-mef2 transcription factor identifies it as a controller of differentiation in multiple muscle cell types; it is the first such gene to be described.
openaire   +2 more sources

Cardiolipin content, linoleic acid composition, and tafazzin expression in response to skeletal muscle overload and unload stimuli

open access: yesScientific Reports, 2017
Cardiolipin (CL) is a unique mitochondrial phospholipid that, in skeletal muscle, is enriched with linoleic acid (18:2n6). Together, CL content and CL 18:2n6 composition are critical determinants of mitochondrial function. Skeletal muscle is comprised of
Val A. Fajardo   +4 more
doaj   +1 more source

Endurance training facilitates myoglobin desaturation during muscle contraction in rat skeletal muscle. [PDF]

open access: yes, 2015
At onset of muscle contraction, myoglobin (Mb) immediately releases its bound O2 to the mitochondria. Accordingly, intracellular O2 tension (PmbO2) markedly declines in order to increase muscle O2 uptake (mVO2).
Furuichi, Yasuro   +9 more
core   +1 more source

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