Results 81 to 90 of about 16,644 (257)

Enteric-coated sodium bicarbonate supplementation improves high-intensity cycling performance in trained cyclists [PDF]

, 2020
Purpose: Enteric-coated sodium bicarbonate (NaHCO3) can attenuate gastrointestinal (GI) symptoms following acute bicarbonate loading, although the subsequent effects on exercise performance have not been investigated.
A Grafen, AB Heibel, AH Lancha Junior, AJ Carr, AJ Carr, AM Jones, AW Midgley, B Saunders, B Thompson, CR Correia-Oliveira, D Bishop, D Lakens, D Micklewright, DJ Peart, DL Costill, DPM Maclaren, F Faul, G Atkinson, GA Borg, GH Raymer, H Westerblad, J Cohen, JAC Barbosa, JC Siegler, JC Siegler, JC Siegler, K DePauw, K Thomas, L Spriet, LA Gough, LA Turnberg, LE Kahle, LG Matson, LM Burke, LR McNaughton, MG Hollidge-Horvat, MJ Callahan, MJ Price, NP Hilton, NP Hilton, P Miller, PB Gastin, PM Christensen, PR Kinnear, RH Fitts, RL Jones, SJ Baker, SK Deb, SL Cameron, SP Cairns, SS Davis   +50 more
core   +1 more source

Neutrophil‐Driven Cascade‐Targeted Nanocarriers Restore Mitochondrial Homeostasis to Ameliorate Renal Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma, Yang Li, Shen Lin, Feifan Chu, Gaozhan Ren, Yinhui Mao, Mingzhi Wu, Yuning Ma, Qiwei Ji, Zujie Chen, Jinzhong Ji, Mingxin Sun, Yongpeng Xu, Xiaoli Sun, Longguang Tang, Hao Zhou   +15 more
wiley   +1 more source

Behavioural interventions for people living with adult-onset primary dystonia : a systematic review [PDF]

, 2016
Background: Primary dystonia is a chronic neurological movement disorder that causes abnormal muscle movements. Pain and emotional distress may accompany these physical symptoms.
Bernstein, Celia J., Davies, G., Ellard, David R., Hertenstein, E., Sandhu, Harbinder, Tang, Nicole K. Y., Underwood, Martin   +6 more
core   +2 more sources

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

Effects of Coenzyme Q10 on Statin‐Induced Myopathy: An Updated Meta‐Analysis of Randomized Controlled Trials

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Previous studies have demonstrated a possible association between the induction of coenzyme Q10 (CoQ10) after statin treatment and statin‐induced myopathy.
Hua Qu, Ming Guo, Hua Chai, Wen‐ting Wang, Zhu‐ye Gao, Da‐zhuo Shi   +5 more
doaj   +1 more source

Influence of a six month endurance exercise program on the immune function of prostate cancer patients undergoing Antiandrogen or Chemotherapy: design and rationale of the ProImmun study [PDF]

, 2013
Background: Exercise seems to minimize prostate cancer specific mortality risk and treatment related side effects like fatigue and incontinence. However the influence of physical activity on the immunological level remains uncertain. Even prostate cancer
Baumann, Freerk T., Bloch, Wilhelm, Jäger, Elke, Zimmer, Philipp, Zopf, Eva Maria   +4 more
core   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

Relationship Between Muscle Cramps and Diabetic Retinopathy in Patients with Type 2 Diabetes

Diabetes, Metabolic Syndrome and Obesity, 2022
Huiqing Hu,1 Chuan Wang,1– 4 Kai Liang,1– 4 Qin He,1 Jia Song,1 Xinghong Guo,1 Xinguo Hou,1– 4 Li Chen,1– 4 Fei Yan1– 4 1Department of Endocrinology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, People’s Republic of ...
Huiqing Hu, Wang C, Liang K, He Q, Song J, Guo X, Hou X, Chen L, Yan F   +8 more
doaj  

Focal dystonia and the Sensory-Motor Integrative Loop for Enacting (SMILE). [PDF]

, 2014
Performing accurate movements requires preparation, execution, and monitoring mechanisms. The first two are coded by the motor system, the latter by the sensory system. To provide an adaptive neural basis to overt behaviors, motor and sensory information
Ionta, S., Lefebvre, J., Murray, M.M., Perruchoud, D.   +3 more
core   +2 more sources

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source