Abstract Objective Treatment selection for infantile epileptic spasms syndrome (IESS) is complex and multifaceted, and currently no electroencephalogram (EEG) biomarkers can guide this decision by predicting treatment response. We tested the predictive value of phase–amplitude coupling (PAC) as IESS patients are known to have elevated PAC.
Soudeh Mostaghimi +6 more
wiley +1 more source
Genetic landscape of patients with atypical absence status epilepticus: A systematic review
Abstract Atypical absence status epilepticus (AASE) is a rare subtype of nonconvulsive status epilepticus (NCSE), characterized by clouding of consciousness and continuous or fluctuating epileptiform activity, generally at a frequency below 3 Hz. Only sparse literature exists on the genetic conditions associated with it.
Maria Cristina Cioclu +2 more
wiley +1 more source
A founder variant in the RYR1 gene is associated with hyperCKemia, myalgia and muscle cramps. [PDF]
Segarra-Casas A +16 more
europepmc +1 more source
Review of articular cartilage repair techniques and their application in the horse
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton +2 more
wiley +1 more source
The Effect of Muscle Cramps During Hemodialysis on Quality of Life and Habitual Physical Activity. [PDF]
Kot G +4 more
europepmc +1 more source
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li +15 more
wiley +1 more source
Programmable crack dynamics engineering enables flexible strain sensors with high linearity
First‐decoupling theoretical framework of crack evolution elucidating the control methods, mechanistic insights, and structure‐activity relationships is established. Crack propagation from uncontrollable randomness systematically evolves into spatially ordered states.
Chunjin Wu +9 more
wiley +1 more source
The RELAX randomized controlled trial: Stretching versus meditation for nocturnal muscle cramps. [PDF]
Tapper EB +8 more
europepmc +1 more source
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
Placebo-Controlled, Randomized Double-Blind N-Of-1 Trial to Study Safety and Potential Efficacy of TJ-68 for Improving Muscle Cramps in Patients With Amyotrophic Lateral Sclerosis: A Pilot Study. [PDF]
Mitsumoto H +10 more
europepmc +1 more source

