Results 151 to 160 of about 19,233,520 (354)

MANDIBULAR SHAPE IN MYOSTATIN-DEFICIENT MICE: A GEOMETRIC MORPHOMETRIC ANALYSIS [PDF]

, 2012
The relationship between muscle function and mandibular morphology is unclear. Manipulating the size or function of muscle and then observing the effect on adjacent bone is one way to explore this relationship.
Johnston, Fayth
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Muscle activity of the stance knee in elite race walkers [PDF]

, 2011
The purpose of this study was to compare knee muscle activity in race walkers with different knee extension patterns. Three international athletes walked over two force plates recording at 1000 Hz.
Bissas, A, Drake, A, Hanley, B
core   +1 more source

The Importance of Extracellular Matrix in Skeletal Muscle Development and Function

, 2016
Skeletal muscle tissue makes up approximately 40% of the total body mass in adult mammals. Contractile muscle fibers building skeletal muscle tissue are coated by an extracellular matrix material (ECM), accounting for 1–10% of the muscle mass. The ECM in
K. Grzelkowska-Kowalczyk
semanticscholar   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Does longer-muscle length resistance training cause greater longitudinal growth in humans? A systematic review

Sports Medicine and Health Science
Background: This paper aimed to systematically review the literature regarding the effects of resistance training (RT) performed at longer-muscle length (LML) versus shorter-muscle length (SML) on proxy measurements for longitudinal hypertrophy. Methods:
Milo Wolf, Patroklos Androulakis Korakakis, Michael D. Roberts, Daniel L. Plotkin, Martino V. Franchi, Bret Contreras, Menno Henselmans, Stian Larsen, Brad J. Schoenfeld   +8 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Improving genomic prediction accuracy of pig reproductive traits based on genotype imputation using preselected markers with different imputation platforms

Animal
Genomic prediction has been widely applied to the pig industry and has greatly accelerated the progress of genetic improvement in pigs. With the development of sequencing technology and price reduction, more and more genotype imputation panels of pig ...
J. Sun, J. Wei, Y. Pan, M. Cao, X. Li, J. Xiao, G. Yang, T. Yu   +7 more
doaj   +1 more source