Results 151 to 160 of about 16,618,401 (319)

The IDB: Vol. 24, no. 9-10, September-October 1997

, 1997
The IDB reports on economic and social development trends in Latin America and the Caribbean and on the activities of the Bank.
Inter-American Development Bank
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Lactate treatment improves brain biochemistry and cognitive function in transgenic Alzheimer’s and wild-type mice

Scientific Reports
Lactate, a well-known metabolite and signalling molecule, holds therapeutic potential for neurodegenerative diseases. Here, we investigated the effects of chronic lactate treatment on cognition and molecular biomarkers in the 5XFAD mouse model of ...
Imen Belhaj, Ingrid Åmellem, Can H. Tartanoglu, Hanne M. Weidemann, Evan M. Vallenari, Mingyi Yang, Farrukh A. Chaudhry, Magnar Bjørås, Jon Storm-Mathisen, Linda Hildegard Bergersen   +9 more
doaj   +1 more source

Genetic Signatures of Competitive Performance in Burmese Gamecocks: A Transcriptomic Analysis

Biology
Understanding the genetic basis of high-performance animals is vital for biological insight and breeding. This study aimed to identify genetic factors distinguishing champion gamecocks (Gallus gallus domesticus) from less successful ones, representing ...
Supawadee Piratae, Chanistha Yamtubtim, Thanitaporn Nonsri, Panpanit Poomprasert, Tarid Purisotayo   +4 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

IDB America: Vol. 26, no. 1-2, January-February 1999

, 1999
IDB America reports on economic and social development trends in Latin America and the Caribbean and on the activities of the IDB.
Inter-American Development Bank
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Response of maize to different nutrient sources under different landscape positions in cereal mixed farming systems of tropical agroecosystems

Agrosystems, Geosciences & Environment
Nutrient omission trials were conducted on farmers’ fields in 2020 and 2022. The experiment included nine treatments: three treatments with nitrogen (N), phosphorus (P), potassium (K), sulfur (S), zinc (Zn), and boron (B) as individual, blended, and ...
Getachew Agegnehu, Zerfu Bazie, Gizaw Desta, Kassu Tadesse, Gizachew Legesse, Hirut Birhanu, Habtamu Getnet, Ayalew Addis, Tarekegn Yibabie, Beamlaku Alemayehu, Fayisa Bulo, Mulugeta Demiss, Tilahun Amede, Abiro Tigabie, John Wendt, Latha Nagarajan, Upendra Singh, Zachary P. Stewart   +17 more
doaj   +1 more source

IDB America: Vol. 26, no. 11-12, November-December 1999

, 1999
IDB America reports on economic and social development trends in Latin America and the Caribbean and on the activities of the IDB.
Inter-American Development Bank
core   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source