Results 31 to 40 of about 1,049,833 (316)

A Novel lnc-RNA, Named lnc-ORA, Is Identified by RNA-Seq Analysis, and Its Knockdown Inhibits Adipogenesis by Regulating the PI3K/AKT/mTOR Signaling Pathway

Cells, 2019
Obesity is closely associated with numerous adipogenic regulatory factors, including coding and non-coding genes. Long noncoding RNAs (lncRNAs) play a major role in adipogenesis.
Rui Cai, Guorong Tang, Que Zhang, Wenlong Yong, Wanrong Zhang, Junying Xiao, Changsheng Wei, Chun He, Gongshe Yang, Weijun Pang   +9 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Identification of porcine fast/slow myogenic exosomes and their regulatory effects on lipid accumulation in intramuscular adipocytes

Journal of Animal Science and Biotechnology
Background Pork quality is affected by the type of muscle fibers, which is closely related to meat color, tenderness and juiciness. Exosomes are tiny vesicles with a diameter of approximately 30–150 nm that are secreted by cells and taken up by recipient
Tiantian Zhao, Tingting Tian, He Yu, Chaoyue Cao, Ziyi Zhang, Zhaozhao He, Zeqiang Ma, Rui Cai, Fengna Li, Weijun Pang   +9 more
doaj   +1 more source

Digital mapping of Ghana’s soil properties and nutrients: performance of spline and weighted average approaches

Geoderma
Soil fertility is a critical factor in sustaining crop productivity and meeting the food demands of the world’s growing population. Assessing the fertility status of soil allows for the adoption of targeted agricultural practices to enhance crop yields ...
Kora B.D. Simperegui, Anselme K.K. Kouame, Benjamin Kwesie, Prem S. Bindraban, William Adzawla, Eric Asamoah, Mohamed El Gharous   +6 more
doaj   +1 more source

Research Note: Increased myostatin expression and decreased expression of myogenic regulatory factors in embryonic ages in a quail line with muscle hypoplasia

Poultry Science, 2021
Genetic selection of quail for a low body weight for more than 80 generations established a low-weight (LW) Japanese quail line that has been previously characterized to have a muscle hypoplasia phenotype.
Dong-Hwan Kim, Young Min Choi, Yeunsu Suh, Sangsu Shin, Joonbum Lee, Seongsoo Hwang, Sang Suk Lee, Kichoon Lee   +7 more
doaj   +1 more source

Skeletal Muscle Development and Regeneration

Stem Cells and Development, 2007
In the late stages of muscle development, a unique cell population emerges that is a key player in postnatal muscle growth and muscle regeneration. The location of these cells next to the muscle fibers triggers their designation as satellite cells. During the healing of injured muscle tissue, satellite cells are capable of forming completely new muscle
Grefte, S., Kuijpers-Jagtman, A.M., Torensma, R., Hoff, J.W. Von den   +3 more
openaire   +4 more sources

Cardiac muscle regeneration: lessons from development [PDF]

Genes & Development, 2011
The adult human heart is an ideal target for regenerative intervention since it does not functionally restore itself after injury yet has a modest regenerative capacity that could be enhanced by innovative therapies. Adult cardiac cells with regenerative potential share gene expression signatures with early fetal progenitors that give rise to multiple ...
Mercola M, Ruiz-Lozano P, Schneider MD
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Characteristics and functions of DNA N(6)-methyladenine in embryonic chicken muscle development

Poultry Science, 2023
: DNA N(6)-methyladenine (DNA-6mA) is a new epigenetic mark in eukaryotes, the distribution and functions of which in genomic DNA remain unknown. Although recent studies have suggested that 6mA is present in multiple model organisms and is dynamically ...
Maosen Yang, Dong Leng, Bo Zeng, Tao Wang, Zhongxian Xu, Diyan Li   +5 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source