Results 101 to 110 of about 1,375,049 (303)

Along- and cross-muscle fiber shear moduli in skeletal muscle

Journal of Biomechanics
Abstract The material properties of muscle play a central role in how muscle resists joint motion, transmits forces internally, and repairs itself. While many studies have evaluated muscle’s tensile material properties, few have investigated muscle’s shear properties.
Ridhi Sahani, William E. Reyna, Thomas J. Royston, Eric J. Perreault, Daniel Ludvig   +4 more
openaire   +3 more sources

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Optimizing the methodology for precise estimation of skeletal muscle fiber type proportions in humans

Scientific Reports
Isolating individual muscle fibers and characterizing their myosin heavy chain (MHC) content using SDS-PAGE has become an increasingly common method for describing skeletal muscle fiber type proportions.
Nathan Serrano, Matthew R. Buras, Lori R. Roust, Eleanna De Filippis, Christos S. Katsanos   +4 more
doaj   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Preliminary Immunohistochemical Assessment of Slow-Fiber Distribution and Clustering in Skeletal Muscles of 4-Week- and 6-Month-Old Pigs

Animals
Type I (slow-twitch) muscle fibers differ in proportion among skeletal muscles, but their local spatial organization remains poorly characterized. This preliminary cross-sectional study investigated whether muscle-specific characteristics were reflected ...
Mutsumi Furukawa, Minami Yanagihara, Miyuko Ohta, Akihiro Kakuzen, Nagomi Takeuchi, Eiki Asai, Ryota Hirakawa, Jahidul Islam, Tomonori Nochi   +8 more
doaj   +1 more source

Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin beta-4 in the dystrophin deficient mouse.

PLoS ONE, 2010
Thymosin beta-4 (Tbeta4) is a ubiquitous protein with many properties relating to cell proliferation and differentiation that promotes wound healing and modulates inflammatory mediators.
Christopher F Spurney, Hee-Jae Cha, Arpana Sali, Gouri S Pandey, Emidio Pistilli, Alfredo D Guerron, Heather Gordish-Dressman, Eric P Hoffman, Kanneboyina Nagaraju   +8 more
doaj   +1 more source

Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor gamma coactivator 1alpha [PDF]

, 2010
Exercise triggers a pleiotropic response in skeletal muscle, which results in a profound remodeling of this tissue. Physical activity-dependent muscle fiber plasticity is regulated by a number of distinct signaling pathways.
Handschin, C.
core   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

ULTRASTRUCTURE OF THE Z LINE OF SKELETAL MUSCLE FIBERS [PDF]

The Journal of Cell Biology, 1971
A new model of Z-line structure in skeletal muscle is proposed. Unlike previous models it is capable of explaining the two apparently inconsistent lattice arrangements seen in thin sections, i.e., the "basket weave" lattice and the smaller lattice recently reported in the literature. The model is based on four looping helical strands derived from the I
openaire   +2 more sources

New insights in the regulation of skeletal muscle PGC-1α by exercise and metabolic diseases [PDF]

, 2013
Skeletal muscle energy metabolism is severely impaired in insulin resistant and type 2 diabetic patients. In particular, deregulated transcription of oxidative metabolism genes has been linked to the development of non-communicable metabolic diseases ...
Handschin, Christoph, Pérez-Schindler, Joaquín   +1 more
core   +1 more source