Results 171 to 180 of about 11,850 (212)

Calcium sensitivity of fast‐and slow‐twitch human muscle fibers

Muscle & Nerve, 1989
AbstractMuscle fibers from the lateral gastrocnemius muscles of five normal adult males were chemically skinned (sarcolemma disrupted) and each fiber was divided into two parts for histochemical determination of fiber type and calcium‐induced tension measurements. The calcium concentration associated with half‐maximal tension was 2.5 μM for fast‐twitch
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Transcriptional regulation of acetylcholinesterase-associated collagen ColQ in fast- and slow-twitch muscle fibers

Chemico-Biological Interactions, 2005
The presence of a collagenous protein (ColQ) characterizes the collagen-tailed forms of acetylcholinesterase (AChE) and butyrylcholinesterase at vertebrate neuromuscular junctions, which is tethered in the synaptic basal lamina. ColQ subunits, differing mostly by their signal sequences, are encoded by transcripts ColQ-1 and ColQ-1a, which are ...
Ting, Annie, Siow, Nina L., Kong, Lingwei, Tsim, Karl Wah Keung   +3 more
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Resting tension characteristics in differentiating intact rat fast- and slow-twitch muscle fibers

Journal of Applied Physiology, 2003
The postnatal changes in resting muscle tension were investigated at 20°C by using small muscle fiber bundles isolated from either the extensor digitorum longus or the soleus of both neonatal (7–21 days old) and adult rats. The results show that the tension-extension characteristics of the bundles depended on the age of the rats. For example, both the
Mutungi, Gabriel, Trinick, John, Ranatunga, K. W.   +2 more
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Mechanical efficiency of fast- and slow-twitch muscle fibers in man during cycling

Journal of Applied Physiology, 1979
The influence of different percentages of slow-twitch (ST) and fast-twitch (FT) fibers in vastus lateralis on delta efficiency expressed by delta work (x)/delta energy liberation (y) in y = a + bx was studied in six subjects during cycling on an ergometer at 60 or 100 rpm at work loads below 80% of VO2max.
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VK2 regulates slow-twitch muscle fibers expression and mitochondrial function via SIRT1/SIRT3 signaling

Nutrition, 2022
Skeletal muscle accounts for 80% of whole body insulin-stimulated glucose uptake, and it plays a key role in preventing and curing obesity and insulin resistance (IR). Vitamin K2 (VK2) plays a beneficial role in improving mitochondrial function through SIRT1 signaling in high-fat diet (HFD)-induced mice and palmitate acid (PA)-treated C2C12 cells.
Xiangni, Su, Jian, Zhou, Wenchen, Wang, Caocao, Yin, Feng, Wang   +4 more
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Electromyographic activation and proportion of fast versus slow twitch muscle fibers: A genetic disposition for psychogenic muscle tension?

International Journal of Psychophysiology, 1993
17 right-handed males volunteered for an experiment that compared task-related patterns of electromyographic (EMG) activation with data from muscle biopsy on proportion of slow-twitch ((ST) aerobic) to fast-twitch ((FT) anaerobic) muscle fibers. The biopsy was taken from the right-leg gastrocnemius muscle after EMG measurement from that area of the leg
S, Svebak, E T, Braathen, O M, Sejersted, B, Bowim, S, Fauske, J C, Laberg   +5 more
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Denervation produces different single fiber phenotypes in fast- and slow-twitch hindlimb muscles of the rat

American Journal of Physiology-Cell Physiology, 2006
Using a single, mechanically skinned fiber approach, we tested the hypothesis that denervation (0 to 50 days) of skeletal muscles that do not overlap in fiber type composition [extensor digitorum longus (EDL) and soleus (SOL) muscles of Long-Evans hooded rats] leads to development of different fiber phenotypes.
Patterson, Michael., Stephenson, Gabriela., Stephenson, Dimitrie.   +2 more
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Diaphragm Assessment in Mice Overexpressing Phospholamban in Slow‐Twitch Type I Muscle Fibers

The FASEB Journal, 2016
Phospholamban (PLN) is a small transmembrane protein that regulates the sarco(endo)plasmic reticulum Ca 2+ ‐ATPase (SERCA) pump through direct physical interactions. Recent work published by our laboratory revealed that when PLN was transgenetically overexpressed in mice (
Paige J. Chambers, Val Andrew Fajardo, Russell Tupling   +2 more
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Differential effects of peroxynitrite on contractile protein properties in fast- and slow-twitch skeletal muscle fibers of rat

Journal of Applied Physiology, 2011
Oxidative modification of contractile proteins is thought to be a key factor in muscle weakness observed in many pathophysiological conditions. In particular, peroxynitrite (ONOO−), a potent short-lived oxidant, is a likely candidate responsible for this contractile dysfunction. In this study ONOO− or 3-morpholinosydnonimine (Sin-1, a ONOO− donor) was
T L, Dutka, J P, Mollica, G D, Lamb
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Phytol Promotes the Formation of Slow-Twitch Muscle Fibers through PGC-1α/miRNA but Not Mitochondria Oxidation

Journal of Agricultural and Food Chemistry, 2017
Phytol is a side chain of chlorophyll belonging to the side-chain double terpenoid. When animals consume food rich in chlorophyll, phytol can be broken down to phytanic acid after digestion. It was reported that feeding animals with different varieties and levels of forage could significant improve pH and marbling score of steer and lamb carcasses, but
Kelin Yang, Lina Wang, Gan Zhou, Xiajing Lin, Jianlong Peng, Leshan Wang, Lv Luo, Jianbin Wang, Gang Shu, Songbo Wang, Ping Gao, Xiaotong Zhu, Qianyun Xi, Yongliang Zhang, Qingyan Jiang   +14 more
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