Results 91 to 100 of about 1,793,126 (357)

Effects of Chronic Akt/mTOR Inhibition by Rapamycin on Mechanical Overload–Induced Hypertrophy and Myosin Heavy Chain Transition in Masseter Muscle

Journal of Pharmacological Sciences, 2013
To examine the effects of the Akt/mammalian target of rapamycin (mTOR) pathway on masseter muscle hypertrophy and myosin heavy chain (MHC) transition in response to mechanical overload, we analyzed the effects of bite-opening (BO) on the hypertrophy and ...
Daisuke Umeki, Yoshiki Ohnuki, Yasumasa Mototani, Kouichi Shiozawa, Takayuki Fujita, Yoshiki Nakamura, Yasutake Saeki, Satoshi Okumura   +7 more
doaj   +1 more source

Nanogel Integrated Zwitterionic Injectable Hydrogel with Sequential Drug‐Releasing Capability for the Programmable Repair of Spinal Cord Injury

Advanced Science, EarlyView.
A novel drug‐loaded D/P‐g‐PSB nanogel‐incorporated hydrogel by the electrostatic attraction‐driven self‐assembling process. Sequential drug releasing property (melatonin is released first by physical diffusion, and then ibuprofen is released as the charge shielding effect and hydrogel degradation). This ion‐sensitive hydrogel platform with sequentially
Zhijian Wei, Susu Huang, Wencan Zhang, Jiayao Wen, Xiaolong Zhou, Wei He, Xiaoye Yang, Haifeng Wang, Guangxi Zhai, Bin Shi, Lin Jin, Dachuan Wang, Shiqing Feng, Lei Ye   +13 more
wiley   +1 more source

Phosphoproteomic mapping reveals distinct signaling actions and activation of protein synthesis and muscle hypertrophy by Isthmin-1 [PDF]

, 2022
Meng Zhao, Niels Banhos Danneskiold‐Samsøe, Lívia Uličná, Quennie Nguyen, Laëtitia Voilquin, David E. Lee, James P. White, Zewen Jiang, Nickeisha Cuthbert, Shrika Paramasivam, Ewa Bielczyk-Maczyńska, Capucine Van Rechem, Katrin J. Svensson   +12 more
openalex   +1 more source

Idiopathic masseter muscle hypertrophy.

Ethiopian journal of health sciences, 2012
Benign Masseteric Hypertrophy is a relatively uncommon condition that can occur unilaterally or bilaterally. Pain may be a symptom, but most frequently a clinician is consulted for cosmetic reasons. In some cases prominent Exostoses at the angle of the mandible are noted.
Kebede, B, Megersa, S
openaire   +2 more sources

The role of raptor in the mechanical load‐induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy

The FASEB Journal, 2018
It is well known that an increase in mechanical loading can induce skeletal muscle hypertrophy, and a long standing model in the field indicates that mechanical loads induce hypertrophy via a mechanism that requires signaling through the mechanistic ...
Jae-Sung You, Rachel M. McNally, Brittany L. Jacobs, Rachel E. Privett, D. Gundermann, Kuan-Hung Lin, Nathaniel D. Steinert, C. Goodman, T. Hornberger   +8 more
semanticscholar   +1 more source

Promoting Autophagy Mitigates Stress‐Induced Remodeling in Patient iPSC‐CMs with the Phospholamban R9C Mutation

Advanced Science, EarlyView.
The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu, Yawei Shen, Robert J. Barndt, Karim Sallam, Ying Tang, Cameron E. Brown, Xiao Li, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu   +10 more
wiley   +1 more source

Isolated unilateral temporalis muscle hypertrophy: first case in an Indo-Aryan

Nepal Journal of Neuroscience, 2020
Unilateral hypertrophy of temporalis muscle (isolated type) is extremely rare and only 14 cases have been reported in English literature since 1990. Although no definitive etiology is identified, stress and bruxism are among the many factors are linked ...
Ali Niyaf, Kiran Niraula, Shiara Zahir, Mohamed Sajuan Mushrif   +3 more
doaj   +1 more source

Recent Perspectives Regarding the Role of Dietary Protein for the Promotion of Muscle Hypertrophy with Resistance Exercise Training

Nutrients, 2018
Skeletal muscle supports locomotion and serves as the largest site of postprandial glucose disposal; thus it is a critical organ for physical and metabolic health.
Tanner Stokes, Amy J. Hector, Robert W Morton, C. McGlory, Stuart M Phillips   +4 more
semanticscholar   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy

bioRxiv, 2019
We aimed to investigate a novel and uncharacterised E3 ubiquitin ligase in skeletal muscle atrophy, recovery from atrophy/injury, anabolism and hypertrophy.
Robert A. E. Seaborne, David C. Hughes, D. Turner, D. Owens, Leslie M. Baehr, P. Gorski, E. Semenova, O. V. Borisov, A. Larin, D. Popov, E. Generozov, H. Sutherland, I. Ahmetov, Jonathan C. Jarvis, S. Bodine, A. Sharples   +15 more
semanticscholar   +1 more source