Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
<i>WNT7A</i> mRNA Lipid Nanoparticles Promote Muscle Hypertrophy and Reduce Fatty Infiltration. [PDF]
Santiago LM +8 more
europepmc +1 more source
ABSTRACT Purpose To investigate the impact of intra/extracellular water exchange (WX) on quantitative dynamic contrast‐enhanced (DCE) MRI in patients with severe aortic stenosis (AS). The aims were to compare low‐dose (WX insensitive) and high‐dose (WX sensitive) DCE‐MRI measurements, and to compare data acquired before and after aortic valve ...
Alex Makins +5 more
wiley +1 more source
Ladder-climbing resistance training stimulates upper limb flexor digitorum profundus muscle hypertrophy in rats. [PDF]
Kwon I.
europepmc +1 more source
ABSTRACT Introduction Differentiating bladder outlet obstruction (BOO) from detrusor underactivity (DU) remains a major unmet need in the management of lower urinary tract symptoms in men. Although pressure–flow urodynamics provide a definitive physiological classification, their invasiveness limits their widespread use.
Sehwan Kim +3 more
wiley +1 more source
Nutritional interventions in muscle hypertrophy research: a scientometric analysis within the context of resistance training (1992-2025). [PDF]
Chen W.
europepmc +1 more source
ABSTRACT Purpose To investigate the adenosine receptor (AR) mechanism underlying bladder outlet obstruction (BOO)‐related bladder dysfunction, we examined the expression level of AR subtypes in bladder tissues, and the effects of AR subtypes A2B & A3 modulation on bladder activity using male BOO rats, and Dahl rats with A2B receptor deletion. Materials
Masahiro Kurobe +8 more
wiley +1 more source
A professional assessment of training plans for muscle hypertrophy and maximal strength developed by generative artificial intelligence. [PDF]
Havers T +6 more
europepmc +1 more source
Fear‐Avoidance and Overactive Bladder: Toward a Mechanism‐Informed Model of Care
ABSTRACT Aims Overactive bladder (OAB) is associated with substantial psychological burden, yet existing biopsychosocial frameworks acknowledge that psychological factors shape outcomes without explaining the cognitive and behavioral mechanisms through which that influence operates.
Rupal M. Patel, Andrea Wood
wiley +1 more source
Role of Electrically Evoked Muscle Hypertrophy on Spasticity in Persons with Spinal Cord Injury. [PDF]
Wasim MA, Alazzam AM, Gorgey AS.
europepmc +1 more source

