Results 61 to 70 of about 126,847 (293)

Growing sabers: Mandibular shape and biomechanical performance trajectories during the ontogeny of Smilodon fatalis

open access: yesThe Anatomical Record, EarlyView.
Abstract The evolution of organisms can be studied through the lens of developmental systems, as the timing of development of morphological features is an important aspect to consider when studying a phenotype. Such data can be challenging to obtain in fossil amniotes owing to the scarcity of their fossil record. However, the numerous remains of Rancho
Narimane Chatar   +5 more
wiley   +1 more source

Expert Perspective: Diagnostic Approach to Differentiating Juvenile Dermatomyositis From Muscular Dystrophy

open access: yesArthritis &Rheumatology, EarlyView.
Clinical tools that can aid in the diagnostic differentiation of juvenile dermatomyositis from muscular dystrophy.
Jacqueline A. Madison   +9 more
wiley   +1 more source

Identification of Biallelic dystrophin gene variants during maternal carrier testing for Becker muscular dystrophy and review of the DMD exon 49–51 deletion phenotype

open access: yesMolecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
This manuscript summarizes a case of biallelic dystrophin (DMD) variants in a mildly affected female patient and additionally highlights the phenotypic spectrum of one of the patient's two DMD variants, a deletion of exons 49–51. This deletion previously had few reports in the published literature, despite its frequency within our institution's ...
Elizabeth A. Ulm   +3 more
wiley   +1 more source

Frataxin deficiency alters gene expression in Friedreich ataxia derived IPSC‐neurons and cardiomyocytes

open access: yesMolecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
FA is a progressive neurodegenerative disorder, but the primary cause of death is heart disease which occurs in 60% of the patients. Several functions of frataxin have been proposed, but none of them fully explain why its deficiency causes the FA phenotypes nor why the most affected cell types are neurons and cardiomyocytes.
Mariana B. Angulo   +6 more
wiley   +1 more source

Predicting Muscle Thickness Deformation from Muscle Activation Patterns: A Dual-Attention Framework [PDF]

open access: yesarXiv
Understanding the relationship between muscle activation and thickness deformation is critical for diagnosing muscle-related diseases and monitoring muscle health. Although ultrasound technique can measure muscle thickness change during muscle movement, its application in portable devices is limited by wiring and data collection challenges.
arxiv  

Beta2‐adrenergic agonist salbutamol exhibits enantioselective disposition in skeletal muscle of lean young men following oral administration

open access: yesDrug Testing and Analysis, EarlyView.
Oral administration of salbutamol shows enantioselective disposition in human skeletal muscle, favoring the (S)‐enantiomer with higher relative partitioning of the pharmacologically active (R)‐enantiomer in muscle. This is concerning from an anti‐doping point of view because the anabolic properties demonstrated for salbutamol can potentially be ...
Morten Hostrup   +5 more
wiley   +1 more source

Patterned Structure Muscle : Arbitrary Shaped Wire-driven Artificial Muscle Utilizing Anisotropic Flexible Structure for Musculoskeletal Robots [PDF]

open access: yesarXiv
Muscles of the human body are composed of tiny actuators made up of myosin and actin filaments. They can exert force in various shapes such as curved or flat, under contact forces and deformations from the environment. On the other hand, muscles in musculoskeletal robots so far have faced challenges in generating force in such shapes and environments ...
arxiv  

Slow Limb Movements Require Precise Control of Muscle Stiffness [PDF]

open access: yesarXiv, 2015
Slow and accurate finger and limb movements are essential to daily activities, but their neural control and governing mechanics are relatively unexplored. We consider neuromechanical systems where slow movements are produced by neural commands that modulate muscle stiffness.
arxiv  

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