Results 61 to 70 of about 250,975 (359)

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

Advanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali, Mohamed H. Sherif, Nashwa Barakat, Bassant Yahia, Ahmed A. Shokeir, Basel Sitohy   +5 more
wiley   +1 more source

A Critical Evaluation of the Biological Construct Skeletal Muscle Hypertrophy: Size Matters but So Does the Measurement

Frontiers in Physiology, 2019
Skeletal muscle is highly adaptable and has consistently been shown to morphologically respond to exercise training. Skeletal muscle growth during periods of resistance training has traditionally been referred to as skeletal muscle hypertrophy, and this ...
Cody T. Haun, Christopher G. Vann, Brandon M. Roberts, Andrew D. Vigotsky, Brad J. Schoenfeld, Michael D. Roberts   +5 more
doaj   +1 more source

Beyond Mechanical Tension: A Review of Resistance Exercise-Induced Lactate Responses & Muscle Hypertrophy

Journal of Functional Morphology and Kinesiology, 2022
The present review aims to explore and discuss recent research relating to the lactate response to resistance training and the potential mechanisms by which lactate may contribute to skeletal muscle hypertrophy or help to prevent muscle atrophy.
Daniel Lawson, Christopher Vann, Brad J. Schoenfeld, Cody Haun   +3 more
doaj   +1 more source

Molecular Mechanisms of Skeletal Muscle Hypertrophy

Journal of Neuromuscular Diseases, 2021
Skeletal muscle hypertrophy can be induced by hormones and growth factors acting directly as positive regulators of muscle growth or indirectly by neutralizing negative regulators, and by mechanical signals mediating the effect of resistance exercise. Muscle growth during hypertrophy is controlled at the translational level, through the stimulation of ...
Schiaffino S., Reggiani C., Akimoto T., Blaauw B.   +3 more
openaire   +5 more sources

Ventricular androgenic-anabolic steroid-related remodeling: an immunohistochemical study [PDF]

, 2017
Background: Several fatal cases of bodybuilders, following a myocardial infarction after long exposure to androgenicanabolic steroids (AAS), are reported. In recent years, evidence has emerged of cases of heart failure related to AAS consumption, with no
Cecchi, Rossana, Ciallella, Costantino, DI LUCA, Natale Mario, Kimura, Akihiko, Kondo, Toshikazu, Muciaccia, Barbara, Nosaka, Mizuho, Sestili, Cristina   +7 more
core   +1 more source

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source

Hypertrophy Stimulation at the Onset of Type I Diabetes Maintains the Soleus but Not the EDL Muscle Mass in Wistar Rats

Frontiers in Physiology, 2017
Diabetes mellitus induces a reduction in skeletal muscle mass and strength. Strength training is prescribed as part of treatment since it improves glycemic control and promotes increase of skeletal muscle mass. The mechanisms involved in overload-induced
Marco A. S. Fortes, Maria V. M. Scervino, Gabriel N. Marzuca-Nassr, Gabriel N. Marzuca-Nassr, Kaio F. Vitzel, Carlos H. da Justa Pinheiro, Rui Curi, Rui Curi   +7 more
doaj   +1 more source

Role of microRNAs in skeletal muscle hypertrophy [PDF]

Frontiers in Physiology, 2014
Skeletal muscle comprises approximately 40% of body weight, and is important for locomotion, as well as for metabolic homeostasis. Adult skeletal muscle mass is maintained by a fine balance between muscle protein synthesis and degradation. In response to cytokines, nutrients, and mechanical stimuli, skeletal muscle mass is increased (hypertrophy ...
Keisuke Hitachi, Kunihiro Tsuchida
openaire   +4 more sources

Strength Training Prior to Endurance Exercise: Impact on the Neuromuscular System, Endurance Performance and Cardiorespiratory Responses [PDF]

, 2014
This study aimed to investigate the acute effects of two strength-training protocols on the neuromuscular and cardiorespiratory responses during endurance exercise. Thirteen young males (23.2 ± 1.6 years old) participated in this study.
Bottaro, Martim, Cadore, Eduardo Lusa, Conceição, Matheus, Dornelles Schneider, Cláudia, Ferrari, Rodrigo, González-Izal, Miriam, Izquierdo, Mikel, Kruel, Luiz Fernando Martins, Liedtke, Giane Veiga, Pinto, Ronei Silveira, Reistenbach Goltz, Fernanda, Wilhelm, Eurico N.   +11 more
core   +2 more sources

Tunicate‐Inspired Carboxymethyl Cellulose Hydrogel Filler for Treating Age‐Associated Vocal Fold Atrophy

Advanced Healthcare Materials, EarlyView.
The pyrogallol‐conjugated carboxymethylcellulose (CMC‐PG) hydrogel is applicated as a filler for the treatment of presbylaryngis, a vocal fold atrophy. CMC‐PG provides a bulking effect to the vocal folds. CMC‐PG is readily injectable and tissue adhesive, enabling sustained release of growth factor over long period.
Jihoon Jeon, Sang‐Yoon Han, Ji Suk Choi, Soojeong Choi, Dongkyun Shin, Mikyung Shin, Seong Keun Kwon, Seung‐Woo Cho   +7 more
wiley   +1 more source