Results 61 to 70 of about 255,284 (355)

Optimization of the Nonclinical Biological Evaluation of Medical Devices Using Toxicologic Pathology Best Practices

open access: yesAdvanced Healthcare Materials, EarlyView.
Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk   +6 more
wiley   +1 more source

Effect of resistance training mainly depends on mechanical activation of fast-twitch fiber

open access: yesJournal of Physical Fitness and Sports Medicine, 2022
This study conducted a secondary survey based on the hypothesis that the “total mechanical activation of fast-twitch fibers in the muscles determines the effects of muscle hypertrophy”, with resistance training of the knee extensor muscles as the target ...
Sho Hatanaka, Naokata Ishii
doaj   +1 more source

Comparison of upper body strength gains between men and women after 10 weeks of resistance training [PDF]

open access: yes, 2016
Resistance training (RT) offers benefits to both men and women. However, the studies about the differences between men and women in response to an RT program are not conclusive and few data are available about upper body strength response.
Bottaro, Martim   +5 more
core   +4 more sources

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim   +16 more
wiley   +1 more source

Hypertrophy Stimulation at the Onset of Type I Diabetes Maintains the Soleus but Not the EDL Muscle Mass in Wistar Rats

open access: yesFrontiers in Physiology, 2017
Diabetes mellitus induces a reduction in skeletal muscle mass and strength. Strength training is prescribed as part of treatment since it improves glycemic control and promotes increase of skeletal muscle mass. The mechanisms involved in overload-induced
Marco A. S. Fortes   +7 more
doaj   +1 more source

Ventricular androgenic-anabolic steroid-related remodeling: an immunohistochemical study [PDF]

open access: yes, 2017
Background: Several fatal cases of bodybuilders, following a myocardial infarction after long exposure to androgenicanabolic steroids (AAS), are reported. In recent years, evidence has emerged of cases of heart failure related to AAS consumption, with no
Cecchi, Rossana   +7 more
core   +1 more source

Tunicate‐Inspired Carboxymethyl Cellulose Hydrogel Filler for Treating Age‐Associated Vocal Fold Atrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
The pyrogallol‐conjugated carboxymethylcellulose (CMC‐PG) hydrogel is applicated as a filler for the treatment of presbylaryngis, a vocal fold atrophy. CMC‐PG provides a bulking effect to the vocal folds. CMC‐PG is readily injectable and tissue adhesive, enabling sustained release of growth factor over long period.
Jihoon Jeon   +7 more
wiley   +1 more source

A Critical Evaluation of the Biological Construct Skeletal Muscle Hypertrophy: Size Matters but So Does the Measurement

open access: yesFrontiers in Physiology, 2019
Skeletal muscle is highly adaptable and has consistently been shown to morphologically respond to exercise training. Skeletal muscle growth during periods of resistance training has traditionally been referred to as skeletal muscle hypertrophy, and this ...
Cody T. Haun   +5 more
doaj   +1 more source

Sarcoplasmic Hypertrophy in Skeletal Muscle: A Scientific “Unicorn” or Resistance Training Adaptation?

open access: yesFrontiers in Physiology, 2020
Skeletal muscle fibers are multinucleated cells that contain mostly myofibrils suspended in an aqueous media termed the sarcoplasm. Select evidence suggests sarcoplasmic hypertrophy, or a disproportionate expansion of the sarcoplasm relative to myofibril
Michael D. Roberts   +6 more
doaj   +1 more source

Parvalbumin affects skeletal muscle trophism through modulation of mitochondrial calcium uptake

open access: yesCell Reports, 2021
Summary: Parvalbumin (PV) is a cytosolic Ca2+-binding protein highly expressed in fast skeletal muscle, contributing to an increased relaxation rate. Moreover, PV is an “atrogene” downregulated in most muscle atrophy conditions.
Gaia Butera   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy