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The Relationship between Muscle Mass and Muscle Strength in the Elderly
Journal of the American Geriatrics Society, 1991To determine the extent that muscle mass is predictive of muscle strength in the elderly, anthropomorphic estimates of muscle area and impedance measurements of muscle mass and peak isometric muscle strength were obtained in a relatively healthy older population over 65 years of age (mean age = 71.7; n = 218).
R L, Reed +4 more
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Muscle Mass Versus Muscle Strength and Performance: Is Muscle Mass Measurement Alone Enough?
2019In the world of advanced liver disease, no person can deny the loss of physical function that occurs to patients with cirrhosis. As the disease progresses, the physical manifestations of muscle mass loss and reduced physical function are apparent. Providers, patients, and caregivers to patients know this all too well.
Matthew R. Kappus, Pranab Barman
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REGULATION OF MUSCLE MASS BY MYOSTATIN
Annual Review of Cell and Developmental Biology, 2004▪ Abstract Myostatin is a secreted protein that acts as a negative regulator of skeletal muscle mass. During embryogenesis, myostatin is expressed by cells in the myotome and in developing skeletal muscle and acts to regulate the final number of muscle fibers that are formed.
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Effect of testosterone on muscle mass and muscle protein synthesis
Journal of Applied Physiology, 1989We have studied the effect of a pharmacological dose of testosterone enanthate (3 mg.kg-1.wk-1 for 12 wk) on muscle mass and total-body potassium and on whole-body and muscle protein synthesis in normal male subjects. Muscle mass estimated by creatinine excretion increased in all nine subjects (20% mean increase, P less than 0.02); total body ...
R C, Griggs +5 more
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Muscle mass, muscle strength and the renin-angiotensin system
Clinical ScienceAbstract The renin-angiotensin system (RAS) is a classically known circulatory regulatory system. In addition to the previously known multi-organ circulatory form of the RAS, the existence of tissue RASs in individual organs has been well established. Skeletal muscle has also been identified as an organ with a distinct RAS.
Hikari Takeshita +3 more
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Mechanisms of Skeletal Muscle Mass Regulation and Muscle Memory
Acta PhysiologicaABSTRACT Changes in muscle mass and force are mainly related to changes in fiber size. In eukaryotes, DNA‐content and cell size are generally correlated, suggesting the existence of a DNA‐template limitation. This might be particularly important in the skeletal muscle fiber syncytia, which contain 30%–50% less DNA per cytoplasmic ...
Kristian Gundersen +2 more
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Growth of Muscle Tissue and Muscle Mass
1978Muscle tissue consists of cylindrical, multinucleated cells called muscle fibers. A skeletal muscle contains many long fibers that have the ability to contract. This contractile property resides in specialized and interacting proteins localized in myofibrils making up the muscle fiber.
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BMP signaling controls muscle mass
Nature Genetics, 2013Cell size is determined by the balance between protein synthesis and degradation. This equilibrium is affected by hormones, nutrients, energy levels, mechanical stress and cytokines. Mutations that inactivate myostatin lead to excessive muscle growth in animals and humans, but the signals and pathways responsible for this hypertrophy remain largely ...
Sartori R +15 more
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Disorders of Muscle Mass and Tone
Veterinary Clinics of North America: Equine PracticeMuscle disease has various clinical manifestations that range from exertional and non-exertional rhabdomyolysis, fasciculations, weakness, rigidity, stiffness, gait abnormalities, poor performance, and alterations in muscle mass and tone. Neurogenic disorders and non-neurogenic disorders such as primary muscle disease can cause muscle atrophy and ...
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