The secretome of skeletal muscle cells: A systematic review
Background: Proteomic studies of the secretome of skeletal muscle cells can help us understand the processes that govern the synthesis, systemic interactions and organization of skeletal muscle and identify proteins that are involved in muscular ...
Antoine Florin +7 more
doaj +1 more source
Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. [PDF]
Determining the sub-cellular localization of a protein within a cell is often an essential step towards understanding its function. In Caenorhabditis elegans, the relatively large size of the body wall muscle cells and the exquisite organization of their
Barbara Meissner +8 more
doaj +1 more source
Cell signaling is determined partially by the localization and abundance of proteins. Dystroglycan and integrin are both transmembrane receptors that connect the cytoskeleton inside muscle cells to the extracellular matrix outside muscle cells ...
Komala Shivanna +5 more
doaj +1 more source
Dynamics and epigenetic control of PcG proteins during skeletal muscle cell differentiation [PDF]
During skeletal muscle differentiation, signal dependent switches in cell differentiation programs require global rearrangements in repression and activation of lineage specific genes, hence the importance of unravelling epigenetic mechanisms that ...
Prezioso, Carolina
core +1 more source
Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism. [PDF]
Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular ...
Feng Shi +4 more
doaj +1 more source
Nuclei of Non-Muscle Cells Bind Centrosome Proteins upon Fusion with Differentiating Myoblasts [PDF]
Background: In differentiating myoblasts, the microtubule network is reorganized from a centrosome-bound, radial array into parallel fibres, aligned along the long axis of the cell.
Espigat-Georger Aude +11 more
core +2 more sources
Proteomic profiling of Duchenne muscular dystrophy : protein patterns and candidate markers of disease [PDF]
Duchenne muscular dystrophy (DMD) caused by mutations in the dystrophin gene is a severe chronic muscle-wasting disease leading to early loss of ambulation in patients and to death by the third decade.
Escher, Claudia Andrea
core +1 more source
Background The formation of contractile myofibrils requires the stepwise onset of expression of muscle specific proteins. It is likely that elucidation of the expression patterns of muscle-specific sarcomeric proteins is important to understand muscle ...
Abdul-Hussein Saba +2 more
doaj +1 more source
Identification of proteins from interstitium of trapezius muscle in women with chronic myalgia using microdialysis in combination with proteomics. [PDF]
BACKGROUND: Microdialysis (MD) of the trapezius muscle has been an attractive technique to investigating small molecules and metabolites in chronic musculoskeletal pain in human. Large biomolecules such as proteins also cross the dialysis membrane of the
Patrik Olausson +4 more
doaj +1 more source
Long term bed rest with and without vibration exercise countermeasures: Effects on human muscle protein dysregulation [PDF]
The present investigation, the first in the field, was aimed at analyzing differentially, on individual samples, the effects of 55 days of horizontal bed rest, a model for microgravity, on myosin heavy and myosin light chain isoforms distribution (by ...
Blottner, Dieter +32 more
core +1 more source

