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Muscle Proteins [PDF]

, 2019
Muscle proteins, usually in the form of meat and meat products, form an important part of many diets. Muscle is a highly structured tissue, derived mostly from the structures of its component proteins. Muscle proteins can be divided into three classes: the myofibrillar proteins (50% to 60%), including the contractile proteins (actin and myosin) that ...
Boland, Mike, Kaur, Lovedeep, Chian, Feng Ming, Astruc, Thierry   +3 more
openaire   +4 more sources

Fibronectin matrix polymerization regulates smooth muscle cell phenotype through a Rac1 dependent mechanism. [PDF]

PLoS ONE, 2014
Smooth muscle cells are maintained in a differentiated state in the vessel wall, but can be modulated to a synthetic phenotype following injury. Smooth muscle phenotypic modulation is thought to play an important role in the pathology of vascular ...
Feng Shi, Xiaochun Long, Allison Hendershot, Joseph M Miano, Jane Sottile   +4 more
doaj   +1 more source

Expression profiles of muscle disease-associated genes and their isoforms during differentiation of cultured human skeletal muscle cells

BMC Musculoskeletal Disorders, 2012
Background The formation of contractile myofibrils requires the stepwise onset of expression of muscle specific proteins. It is likely that elucidation of the expression patterns of muscle-specific sarcomeric proteins is important to understand muscle ...
Abdul-Hussein Saba, van der Ven Peter F M, Tajsharghi Homa   +2 more
doaj   +1 more source

Proteomic Analysis of Chicken Skeletal Muscle during Embryonic Development

Frontiers in Physiology, 2017
Embryonic growth and development of skeletal muscle is a major determinant of muscle mass, and has a significant effect on meat production in chicken. To assess the protein expression profiles during embryonic skeletal muscle development, we performed a ...
Hongjia Ouyang, Hongjia Ouyang, Zhijun Wang, Zhijun Wang, Xiaolan Chen, Xiaolan Chen, Jiao Yu, Jiao Yu, Zhenhui Li, Zhenhui Li, Qinghua Nie, Qinghua Nie   +11 more
doaj   +1 more source

STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia. [PDF]

PLoS ONE, 2011
Cachexia, or weight loss despite adequate nutrition, significantly impairs quality of life and response to therapy in cancer patients. In cancer patients, skeletal muscle wasting, weight loss and mortality are all positively associated with increased ...
Andrea Bonetto, Tufan Aydogdu, Noelia Kunzevitzky, Denis C Guttridge, Sawsan Khuri, Leonidas G Koniaris, Teresa A Zimmers   +6 more
doaj   +1 more source

Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training

Scientific Reports, 2018
Regular exercise elicits advantageous metabolic adaptations in skeletal muscle, such as improved insulin sensitivity. However, the underpinning molecular mechanisms and the effect of diet on muscle exercise training benefits are unclear.
Maximilian Kleinert, Benjamin L. Parker, Thomas E. Jensen, Steffen H. Raun, Phung Pham, Xiuqing Han, David E. James, Erik A. Richter, Lykke Sylow   +8 more
doaj   +1 more source

The RNA-binding proteins Zfp36l1 and Zfp36l2 act redundantly in myogenesis

Skeletal Muscle, 2018
Background Members of the ZFP36 family of RNA-binding proteins regulate gene expression post-transcriptionally by binding to AU-rich elements in the 3’UTR of mRNA and stimulating mRNA degradation.
Hema Bye-A-Jee, Dhamayanthi Pugazhendhi, Samuel Woodhouse, Patrick Brien, Rachel Watson, Martin Turner, Jennifer Pell   +6 more
doaj   +1 more source

Effects of Low-Load Blood Flow Restriction Training on Muscle Anabolism Biomarkers and Thrombotic Biomarkers Compared with Traditional Training in Healthy Adults Older Than 60 Years: Systematic Review and Meta-Analysis

Life
The aim of this meta-analysis was to determine the effects of low-load blood flow restriction training (LL-BFRT) on muscle anabolism and thrombotic biomarkers compared with the effects of traditional LL training and to analyse the changes in these ...
Raúl Fabero-Garrido, Miguel Gragera-Vela, Tamara del Corral, Marta Hernández-Martín, Gustavo Plaza-Manzano, Ibai López-de-Uralde-Villanueva   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Analysis of cashmere goat meat by label-free proteomics shows that MYL3 is a potential molecular marker of meat toughness

Czech Journal of Animal Science, 2022
The Inner Mongolia cashmere goat is famous for its bright white cashmere fibre. However, little attention is given to the excellent characteristics of this breed's meat. We used label-free proteomics to analyse the total protein content in five different
Yuchun Xie, Nai Rile, Xuewu Li, Haijun Li, Meng Zhao, Tianyu Che, Ting Cai, Zhihong Liu, Jinquan Li   +8 more
doaj   +1 more source