Results 261 to 270 of about 1,366,391 (310)
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Regeneration of skeletal muscle
Cell and Tissue Research, 2011Skeletal muscle has a robust capacity for regeneration following injury. However, few if any effective therapeutic options for volumetric muscle loss are available. Autologous muscle grafts or muscle transposition represent possible salvage procedures for the restoration of mass and function but these approaches have limited success and are plagued by ...
Neill J, Turner, Stephen F, Badylak
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New England Journal of Medicine, 1971
There has been for many years an almost complete lack of communication between the general pathologist and the experimental morphologist on the question of the ability of skeletal muscle to regenerate. I have consistently taught first-year medical students that the difference between muscle regeneration in the lowly salamander on which I work and the ...
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There has been for many years an almost complete lack of communication between the general pathologist and the experimental morphologist on the question of the ability of skeletal muscle to regenerate. I have consistently taught first-year medical students that the difference between muscle regeneration in the lowly salamander on which I work and the ...
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Nanomaterial for Skeletal Muscle Regeneration
Tissue Engineering and Regenerative Medicine, 2022Skeletal muscle has an innate regenerative capacity to restore their structure and function following acute damages and injuries. However, in congenital muscular dystrophies, large volumetric muscle loss, cachexia, or aging, the declined regenerative capacity of skeletal muscle results in muscle wasting and functional impairment.
Gun-Jae Jeong +4 more
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Muscle & Nerve, 1981
AbstractThe historical and current research literature is reviewed with special attention to the role of the satellite cell in the reconstitution of skeletal muscle following damage. Implications for the clinical management of trauma patients are stressed in the light of this new knowledge.
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AbstractThe historical and current research literature is reviewed with special attention to the role of the satellite cell in the reconstitution of skeletal muscle following damage. Implications for the clinical management of trauma patients are stressed in the light of this new knowledge.
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Pattern of skeletal muscle regeneration after reautotransplantation of regenerated muscle
Development, 1986ABSTRACT Autotransplantation of rat extensor digitorum longus muscle results in initial myofibre degeneration and subsequent regeneration from precursor myosatellite cells. To determine what effect a reinjury would have on the regenerative response, in the present.study, once transplanted and regenerated muscles were reinjured by ...
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Desmin and vimentin in regenerating muscles
Muscle & Nerve, 1992AbstractDesmin is a normal constituent of skeletal muscle fibers; vimentin is contained in myoblasts and connective tissue cells. The intracellular localization of both intermediate filament proteins in regenerating rat muscles was investigated by immunohisto‐ and immunocytochemistry. Necrosis was induced by hot Ringer solution.
Bornemann, A., Schmalbruch, Henning
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Some Aspects of Muscle Regeneration
1966Publisher Summary This chapter discusses some aspects of muscle regeneration. Regeneration of striated muscle must produce, to be complete, a multinucleated fiber attached at both ends containing myofibrils that can contract under a nervous stimulus. This is a minimum requirement for a functional restoration.
E H, Betz, H, Firket, M, Reznik
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Thymosins and Muscle Regeneration
2011Thymosins are a family of highly conserved small peptides originally isolated from calf thymus. One representative member of the family is thymosin-β₄ (Tβ₄), a major G-actin-sequestering peptide present in many tissues. In the last decade, various studies have uncovered several important functions for Tβ₄ related to the regeneration of injured tissues ...
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Strategies for Regeneration of Heart Muscle
Critical Reviews™ in Eukaryotic Gene Expression, 2010Regenerative medicine has emerged to the forefront of cardiac research, marrying discoveries in both basic science and engineering to develop viable therapeutic approaches for treating the diseased heart. Signifi cant advancements in gene therapy, stem cell biology, and cardiomyoplasty provide new optimism for regenerating damaged myocardium.
Jacques P, Guyette +2 more
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Gene Transfer in Regenerating Muscle
Human Gene Therapy, 1994We have compared the efficiency of direct gene transfer in normal and regenerating rat skeletal muscle. Muscle necrosis and regeneration was induced by intramuscular injection of bupivacaine in the soleus muscle of adult rats. Plasmids containing beta-galactosidase (beta-gal) or chloramphenicol acetyltransferase (CAT) genes driven by viral promoters ...
Vitadello M +4 more
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