Results 71 to 80 of about 1,366,391 (310)

Impaired Muscle Regeneration in Ob/ob and Db/db Mice

The Scientific World Journal, 2011
In obesity and type 2 diabetes, efficient skeletal muscle repair following injury may be required, not only for restoring muscle structure and function, but also for maintaining exercise capacity and insulin sensitivity.
Mai-Huong Nguyen, Ming Cheng, Timothy J. Koh   +2 more
doaj   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Myo-REG: A Portal for Signaling Interactions in Muscle Regeneration

Frontiers in Physiology, 2019
Muscle regeneration is a complex process governed by the interplay between several muscle-resident mononuclear cell populations. Following acute or chronic damage these cell populations are activated, communicate via cell–cell interactions and/or ...
Alessandro Palma, Andrea Cerquone Perpetuini, Federica Ferrentino, Claudia Fuoco, Cesare Gargioli, Giulio Giuliani, Marta Iannuccelli, Luana Licata, Elisa Micarelli, Serena Paoluzi, Livia Perfetto, Lucia Lisa Petrilli, Alessio Reggio, Marco Rosina, Francesca Sacco, Simone Vumbaca, Alessandro Zuccotti, Luisa Castagnoli, Gianni Cesareni, Gianni Cesareni   +19 more
doaj   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

Regenerating muscle with arginine methylation [PDF]

Transcription, 2017
Protein arginine methyltransferase (PRMT) is a family of nine proteins catalyzing the methylation of arginine residues. They were recently shown to be essential for proper regeneration of skeletal muscles. However, the mechanisms triggering the methylation event, as well as how the methylated substrates regulate muscle stem cell function and fate ...
Roméo S, Blanc, Stéphane, Richard
openaire   +2 more sources

Fully Additive Vertical Organic Electrochemical Transistors on Renewable and Compostable Substrates Enable Ultrasensitive Bioelectronics

Advanced Functional Materials, EarlyView.
Fully additive vertical organic electrochemical transistors (vOECTs) with channel‐length of 226 nm on a 50 µm compostable substrate achieve >106 current modulation and ∼36 mS transconductance. Ion‐selective integration enables 1.1 mA dec−1 sensitivity and 36 µm detection limit, highlighting a scalable platform for sustainable electronics and ...
Giulia Frusconi, Samuele Lavelli, Zsolt M. Kovács‐Vajna, Fabrizio Torricelli   +3 more
wiley   +1 more source

The Effect of Pax3 Over-expression on Myoblast Function [PDF]

, 2009
The paired-box transcription factor 3 (Pax3), is a powerful myogenic regulatory factor during embryo-myogenesis. The expression of Pax3 is involved in determining somitic cell fate, resulting in the formation of the first differentiated muscle, the ...
Brijs, Erik
core  

Frontiers in Skeletal Muscle Wasting, Regeneration and Stem Cells

, 2016
The search for knowledge on cellular and molecular mechanisms involved in skeletal muscle mass homeostasis and regeneration is an exciting scientific area and extremely important to develop therapeutic strategies for neuromuscular disorders and ...
Pinheiro, Carlos Hermano J., Lucas Guimaraes-Ferreira, Carlos Hermano J. Pinheiro, Ferreira, Lucas Guimarães   +3 more
core   +1 more source

CX3CR1 deficiency promotes muscle repair and regeneration by enhancing macrophage ApoE production [PDF]

, 2015
International audienceMuscle injury triggers inflammation in which infiltrating mononuclear phagocytes are crucial for tissue regeneration. The interaction of the CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axis that guides phagocyte infiltration is ...
Boissonnas A., Saclier M., Chazaud, Bénédicte, Benhabiles N., Arnold, Ludovic, Guyon, Elodie, Mounier R., Saclier, Marielle, de Chanville, Camille Baudesson, Hermand, Patricia, Perrin H., Boissonnas, Alexandre, Combadiere C., Perrin, Hélène, Poupel L., Benhabiles, Nora, Combadiere, Christophe, Combadiere, Béhazine, Arnold L., Carpentier W., Hermand P., Carpentier, Wassila, Guyon E., Licata F., Licata, Fabrice, Chazaud B., Poupel, Lucie, Mounier, Rémi, Vilar J., Combadiere B., De Chanville C. B., Vilar, José   +31 more
core   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source