Results 91 to 100 of about 176,030 (314)

Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy

, 2022
Background Human pluripotent stem cell‐derived muscle models show great potential for translational research. Here, we describe developmentally inspired methods for the derivation of skeletal muscle cells and their utility in skeletal muscle tissue ...
Eric N. Olson, Olson, Eric N., Sadman M. Sakib, Shahriyari, Mina, Schmidt, Matthias, Rhonda Bassel‐Duby, Gisa, Verena, Schmidt, Jens, Fischer, André, Tiburcy, Malte, Wolfram‐Hubertus Zimmermann, Mina Shahriyari, Linke, Wolfgang A., Harithaa Anandakumar, Winterhoff, Mandy, Zschüntzsch, Jana, Gabriela Salinas, Islam, Md Rezaul, Rinn, Malte, Salinas-Riester, Gabriela, Bassel-Duby, Rhonda S., Zimmermann, Wolfram-Hubertus, Rika, Anastasia, Wolfgang A. Linke, André Fischer, Orr Shomroni, Andreas Unger, Mandy Winterhoff, Sakib, Sadman M., Jens Schmidt, Anastasia Rika, Verena Gisa, Kaurani, Lalit, Salinas, Gabriela, Zimmermann, Wolfram‐Hubertus, Krüger, Dennis, Unger, Andreas, Jana Zschüntzsch, Anandakumar, Harithaa, Malte Rinn, Bassel‐Duby, Rhonda, Shomroni, Orr, Krüger, Dennis Manfred, Dennis Krüger, Matthias Schmidt, Md Rezaul Islam, Lalit Kaurani, Malte Tiburcy   +47 more
core   +1 more source

HDAC4 Regulates Skeletal Muscle Regeneration via Soluble Factors

Frontiers in Physiology, 2018
Skeletal muscle possesses a high ability to regenerate after an insult or in pathological conditions, relying on satellite cells, the skeletal muscle stem cells.
Alessandra Renzini, Nicoletta Marroncelli, Chiara Noviello, Viviana Moresi, Viviana Moresi, Sergio Adamo   +5 more
doaj   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Muscle Homeostasis and Regeneration [PDF]

, 2020
The book is a collection of original research and review articles addressing the intriguing field of the cellular and molecular players involved in muscle homeostasis and regeneration.

core   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Characteristics of muscle fibers reconstituted in the regeneration process of masseter muscle in an mdx mouse model of muscular dystrophy

, 2006
Mdx mice, which lack dystrophin, were examined for changes in the properties of muscle fibers in the growth process of the masseter muscle at the morphological, protein and transcriptional levels. The slow-type isoform, MyHC-1, and the fast-type isoforms,
김희진
core   +1 more source

LC-MS/MS based metabolomics reveals the mechanism of skeletal muscle regeneration

BMC Musculoskeletal Disorders
Background Skeletal muscle possesses a robust regenerative capacity and can effectively repair itself following injury. However, research on the metabolic changes during skeletal muscle regeneration in large animals remains relatively limited. Therefore,
Lei Yi, Kaiming Wang, Sui Liufu, Wenwu Chen, Bohe Chen, Xiaolin Liu, Caihong Liu, Jingwen Liu, Xin Xu, Haiming Ma   +9 more
doaj   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

A study of the reinnervation of stretch receptors in cat muscle following nerve injury [PDF]

, 1983
An histological investigation into the reinnervation of stretch receptors necessarily requires a reliable staining technique. To achieve this, silver staining has been investigated and standardised.
Boddy, Alan
core  

Neutrophils do not contribute to local tissue damage, but play a key role in skeletal muscle regeneration, in mice injected with Bothrops asper snake venom

, 2015
Local tissue damage induced by crotaline snake venoms includes edema, myonecrosis, hemorrhage, and an inflammatory response associated with a prominent cellular infiltrate.
Zuliani, JP, Chaves, F, Zamuner, SR, Teixeira, CFP, Gutierrez, JM, Fernandes, CM, Fernandes, I, Cruz-Hofling, MA   +7 more
core   +1 more source