Skeletal muscle function underpins muscle spindle abundance [PDF]
Proceedings of the Royal Society B: Biological Sciences, 2022 Muscle spindle abundance is highly variable within and across species, but we currently lack any clear picture of the mechanistic causes or consequences of this variation.
Roger W P Kissane +2 more
exaly +4 more sources
Characterization of muscle spindle afferents in the adult mouse using an in vitro muscle-nerve preparation. [PDF]
PLoS ONE, 2012 We utilized an in vitro adult mouse extensor digitorum longus (EDL) nerve-attached preparation to characterize the responses of muscle spindle afferents to ramp-and-hold stretch and sinusoidal vibratory stimuli. Responses were measured at both room (24°C)
Katherine A Wilkinson +2 more
doaj +3 more sources
The highest region of muscle spindle abundance should be the optimal target of botulinum toxin A injection to block muscle spasms in rats [PDF]
Frontiers in Neurology, 2023 PurposeThe effective relief of muscle spasticity requires prompt solutions in rehabilitation medicine. This study aimed to reveal that the highest region of muscle spindle abundance is the optimal target of botulinum toxin A (BTX-A) injections for ...
Jie Yu +5 more
doaj +2 more sources
Influence of Intervertebral Fixation and Segmental Thrust Level on Immediate Post-Spinal Manipulation Trunk Muscle Spindle Response in an Animal Model [PDF]
Brain Sciences, 2021 Objective: To characterize the effect of unilateral (single and two-level) lumbar facet/zygapophysial joint fixation on paraspinal muscle spindle activity immediately following L4 or L6 high velocity low amplitude spinal manipulation (HVLA-SM) delivered ...
Carla R. Lima +5 more
doaj +2 more sources
Mechanotransduction in the muscle spindle. [PDF]
Pflugers Arch, 2015 The focus of this review is on the principal sensory ending of the mammalian muscle spindle, known as the primary ending. The process of mechanosensory transduction in the primary ending is examined under five headings: (i) action potential responses to defined mechanical stimuli-representing the ending's input-output properties; (ii) the receptor ...
Bewick GS, Banks RW.
europepmc +6 more sources
Modulation of human muscle spindle discharge by arterial pulsations--functional effects and consequences. [PDF]
PLoS ONE, 2012 Arterial pulsations are known to modulate muscle spindle firing; however, the physiological significance of such synchronised modulation has not been investigated.
Ingvars Birznieks +2 more
doaj +3 more sources
The Neurophysiological Impact of Experimentally-Induced Pain on Direct Muscle Spindle Afferent Response: A Scoping Review [PDF]
Frontiers in Cellular Neuroscience, 2021 Background: Musculoskeletal pain disorders are among the leading causes of years lived with disability worldwide representing a significant burden to society.
Carla R. Lima +3 more
doaj +2 more sources
Calcium regulation of muscle spindle mechanosensory afferent function [PDF]
Experimental PhysiologyExtracellular calcium is crucial for the normal function of muscle spindle sensory afferents. They express multiple calcium buffering proteins. Extracellular calcium is essential for recycling of synaptic‐like vesicles (SLVs) in the terminals and for the
Anna Simon +5 more
doaj +2 more sources
Vesicle‐released glutamate is necessary to maintain muscle spindle afferent excitability but not dynamic sensitivity in adult mice [PDF]
Journal of Physiology, 2021 Enoch Kim +2 more
exaly +2 more sources
Assessment of Platelet Rich Plasma Injection on Muscle Spindle Injury in a Rat Model (Histological and Immunohistochemical Study) [PDF]
The Egyptian Journal of Histology, 2023 Introduction: Nowadays, platelet-rich plasma injection (PRP) has become a common treatment in the scope of reconstructive plastic surgery and trauma. PRP contains varies growth factors that accelerate cell regeneration and differentiation.Objective of ...
Yasmin Ramadan +2 more
doaj +1 more source