Regulated Reprogramming in the Regeneration of Sensory Receptor Cells [PDF]
Vision, olfaction, hearing, and balance are mediated by receptors that reside in specialized sensory epithelial organs. Age-related degeneration of the photoreceptors in the retina and the hair cells in the cochlea, caused by macular degeneration and sensorineural hearing loss, respectively, affect a growing number of individuals.
Olivia Bermingham-McDonogh, Thomas Reh
exaly +3 more sources
L-Amino Acids Elicit Diverse Response Patterns in Taste Sensory Cells: A Role for Multiple Receptors. [PDF]
Umami, the fifth basic taste, is elicited by the L-amino acid, glutamate. A unique characteristic of umami taste is the response potentiation by 5' ribonucleotide monophosphates, which are also capable of eliciting an umami taste.
Shreoshi Pal Choudhuri +2 more
doaj +3 more sources
Actin filaments in sensory hairs of inner ear receptor cells. [PDF]
Receptor cells in the ear are excited through the bending of sensory hairs which project in a bundle from their surface. The individual stereocilia of a bundle contain filaments about 5 nm in diameter. The identity of these filaments has been investigated in the crista ampullaris of the frog and guinea pig by a technique of decoration with subfragment ...
Åke Flock, H C Cheung
exaly +3 more sources
Low-density lipoprotein receptor related protein-1 (LRP1)-dependent cell signaling promotes neurotrophic activity in embryonic sensory neurons. [PDF]
Developing sensory neurons require neurotrophic support for survival, neurite outgrowth and myelination. The low-density lipoprotein receptor-related protein-1 (LRP1) transactivates Trk receptors and thereby functions as a putative neurotrophin.
Kazuyo Yamauchi +6 more
doaj +3 more sources
Connectomic mapping of pharyngeal and gut sensory circuits in adult Drosophila [PDF]
Summary: Feeding is regulated by both external sensory signals, such as taste, and internal sensory signals originating from the pharynx and gut.
Dimitrios S. Giakoumas +3 more
doaj +2 more sources
Transduction and adaptation in sensory receptor cells [PDF]
Sensory transduction shares common features in widely different sensory modalities. The purpose of this article is to examine the similarities and differences in the underlying mechanisms of transduction in the sensory receptor cells for vision, olfaction, and hearing.
Torre, Vincent +3 more
openaire +3 more sources
Olfactory bulb and higher processing areas are synaptically interconnected, providing rapid regulation of olfactory bulb circuit dynamics and sensory processing. Short-term plasticity changes at any of these synapses could modulate sensory processing and
Fu-Wen Zhou, Adam C. Puche
doaj +1 more source
Serotonin Receptors and Their Involvement in Melanization of Sensory Cells in Ciona intestinalis
Serotonin (5-hydroxytryptamine (5-HT)) is a biogenic monoamine with pleiotropic functions. It exerts its roles by binding to specific 5-HT receptors (5HTRs) classified into different families and subtypes. Homologs of 5HTRs are widely present in invertebrates, but their expression and pharmacological characterization have been scarcely investigated. In
Silvia Mercurio +4 more
openaire +6 more sources
Metabolic Control of Sensory Neuron Survival by the p75 Neurotrophin Receptor in Schwann Cells [PDF]
We report that the neurotrophin receptor p75 contributes to sensory neuron survival through the regulation of cholesterol metabolism in Schwann cells. Selective deletion of p75 in mouse Schwann cells of either sex resulted in a 30% loss of dorsal root ganglia (DRG) neurons and diminished thermal sensitivity.
Rose M. Follis +9 more
openaire +4 more sources
A possible role for taste receptor cells in surveying the oral microbiome.
Taste receptor cells are sensory specialists that detect chemicals in food and drink. An exciting new report in PLOS Biology suggests that some taste cells could also be involved in immune surveillance like counterparts in the intestine.
Emma M Heisey +1 more
doaj +1 more source

