Results 41 to 50 of about 5,832,680 (299)

The odontoblast as a sensory receptor cell? The expression of TRPV1 (VR-1) channels

Archives of Histology and Cytology, 2005
Previous reports have shown the expression of several mechanosensitive ionic channels on the plasma membrane in odontoblasts, which are the cells responsible for dentin formation. The membrane characteristics of odontoblasts imply that they could play critical roles in the mechano-transduction of fluid displacement within dentinal tubules into the ...
Okumura, R, Shima, K, Muramatsu, T, Nakagawa, K, Shimono, M, Suzuki, T, Magloire, H, Shibukawa, Y   +7 more
openaire   +4 more sources

Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells [PDF]

, 2009
Stem cells, that is, cells that can both reproduce themselves and differentiate into functional cell types, attract much interest as potential aids to healing and disease therapy. Embryonic neural crest is pluripotent and generates the peripheral nervous
Negulyaev, YA, Bennett, DC, Patel, RH, Sviderskaya, EV, Easty, DJ, Sanchez, DP, Lawrence, MA, Anand, P, Korchev, YE   +8 more
core   +1 more source

The sensory system acts with a neuromedin U signaling pathway to mediate food type-dependent effects on lifespan [PDF]

, 2010
In order to survive, the animal uses its sensory system to interpret the complexity of its environment. Interestingly, a subset of sensory neurons, which function in taste or olfaction, has been found to influence the lifespan of C.
Adilov, Bakhtiyor
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Histomorphological and microanatomical characteristics of the olfactory organ of freshwater carp, Cirrhinus reba (Hamilton)

Archives of Polish Fisheries, 2016
The morphoanatomy, cellular organization, and surface architecture of the olfactory apparatus in Cirrhinus reba (Hamilton) is described using light and scanning electron microscopy.
Ghosh Saroj Kumar, Chakrabarti Padmanabha   +1 more
doaj   +1 more source

Sensory nerves in the spotlight of the stem cell niche

Stem Cells Translational Medicine, 2021
Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the marrow in which mesenchymal stem cells are retained and produce new cells throughout life ...
Caroline C. Picoli, Alinne C. Costa, Beatriz G.S. Rocha, Walison N. Silva, Gabryella S.P. Santos, Pedro H.D.M. Prazeres, Pedro A.C. Costa, Anderson Oropeza, Rodrigo A. daSilva, Vasco A.C. Azevedo, Rodrigo R. Resende, Thiago M. Cunha, Akiva Mintz, Alexander Birbrair   +13 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

TRPV1 and TRPA1 in cutaneous neurogenic and chronic inflammation: pro-inflammatory response induced by their activation and their sensitization

Protein & Cell, 2017
Cutaneous neurogenic inflammation (CNI) is inflammation that is induced (or enhanced) in the skin by the release of neuropeptides from sensory nerve endings. Clinical manifestations are mainly sensory and vascular disorders such as pruritus and erythema.
Olivier Gouin, Killian L’Herondelle, Nicolas Lebonvallet, Christelle Le Gall-Ianotto, Mehdi Sakka, Virginie Buhé, Emmanuelle Plée-Gautier, Jean-Luc Carré, Luc Lefeuvre, Laurent Misery, Raphaele Le Garrec   +10 more
doaj   +1 more source

Piezo1-pannexin-1-P2X3 axis in odontoblasts and neurons mediates sensory transduction in dentinal sensitivity

Frontiers in Physiology, 2022
According to the “hydrodynamic theory,” dentinal pain or sensitivity is caused by dentinal fluid movement following the application of various stimuli to the dentin surface.
Sadao Ohyama, Sadao Ohyama, Takehito Ouchi, Maki Kimura, Ryuya Kurashima, Keiko Yasumatsu, Daisuke Nishida, Suzuro Hitomi, Suzuro Hitomi, Sobhan Ubaidus, Hidetaka Kuroda, Hidetaka Kuroda, Shinichirou Ito, Masayuki Takano, Kentaro Ono, Toshihide Mizoguchi, Akira Katakura, Yoshiyuki Shibukawa   +17 more
doaj   +1 more source

Human Mas-related G protein-coupled receptors-X1 induce chemokine receptor 2 expression in rat dorsal root ganglia neurons and release of chemokine ligand 2 from the human LAD-2 mast cell line [PDF]

, 2013
Primate-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are highly enriched in dorsal root ganglia (DRG) neurons and induce acute pain. Herein, we analyzed effects of MRGPR-X1 on serum response factors (SRF) or nuclear factors of activated
Kathrin Rothe (386395), Ingrid Boekhoff, Ingrid Boekhoff (180345), Andreas Breit (180329), Solinski Hans Jürgen, Petermann, Franziska, Andreas Breit, Hans Jürgen Solinski (166922), Rothe Kathrin, Thomas Gudermann, Franziska Petermann, Boekhoff, Ingrid, Breit, Andreas, Boekhoff Ingrid, Rothe, Kathrin, Gudermann, Thomas, Gudermann Thomas, Breit Andreas, Thomas Gudermann (77426), Hans Jürgen Solinski, Petermann Franziska, Franziska Petermann (220017), Solinski, Hans Jürgen, Kathrin Rothe   +23 more
core   +2 more sources