Results 21 to 30 of about 173,264 (311)

Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells [PDF]

, 2008
Neuropilin (NRP) receptors and their class 3 semaphorin (SEMA3) ligands play well-established roles in axon guidance, with loss of NRP1, NRP2, SEMA3A or SEMA3F causing defasciculation and errors in growth cone guidance of peripherally projecting nerves ...
Howard, Beatrice, Christiana Ruhrberg, Quenten Schwarz, Britta J. Eickholt, Beatrice Howard, Vieira, J., Vieira, Joaquim M.; id_orcid, Ruhrberg, C., Howard, B, Ruhrberg, Christiana, Vieira, JM, Schwarz, Quenten, Joaquim M. Vieira, Eickholt, BJ, Schwarz, Q, Eickholt, Britta J., Howard, B., Eickholt, B., Ruhrberg, C, Schwarz, Q.P.   +19 more
core   +1 more source

Mouse embryonic stem cells as a discovery tool in neurobiology [PDF]

, 2012
Mouse ES cells can recapitulate, under suitable tissue culture conditions, early events in neurogenesis. As wildtype or genetically modified ES cells can be grown in unlimited quantities, their differentiation into neurons represents an attractive model
Nikoletopoulou, Vassiliki
core   +1 more source

Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells.

PLoS ONE, 2017
Receptors implicated in cough hypersensitivity are transient receptor potential vanilloid 1 (TRPV1), transient receptor potential cation channel, Subfamily A, Member 1 (TRPA1) and acid sensing ion channel receptor 3 (ASIC3).
Shadia Omar, Rebecca Clarke, Haniah Abdullah, Clare Brady, John Corry, Hanagh Winter, Olivier Touzelet, Ultan F Power, Fionnuala Lundy, Lorcan P A McGarvey, S Louise Cosby   +10 more
doaj   +1 more source

Sensory Mechanisms in Mammalian Touch Receptor Cells [PDF]

Biophysical Journal, 2011
The sense of touch is critical for hand dexterity that allows mammals to recognize and grasp objects. Different qualities of touch are encoded by sensory neurons with distinct properties. Shapes and curvature are encoded by Merkel cell-neurite complexes, which mediate slowly adapting type I (SAI) responses. Merkel cells, which cluster in fingertips and
openaire   +1 more source

Tachykinins stimulate a subset of mouse taste cells. [PDF]

PLoS ONE, 2012
The tachykinins substance P (SP) and neurokinin A (NKA) are present in nociceptive sensory fibers expressing transient receptor potential cation channel, subfamily V, member 1 (TRPV1).
Jeff Grant
doaj   +1 more source

Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]

, 2009
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J, Aldskogius, Hakan, Wegner, M, Hjerling-Leffler, Jens, Kozlova, Elena N, Medvinsky, Alexander, Berens, C, Aldskogius, H, Kozlova, EN, Berens, Christian, Kanaykina, Nadezda, Sandelin, Martin, Schreiner, S, Wegner, Michael, Kanaykina, N, Sandelin, M, Liakhovitskaia, A, Medvinsky, A, Liakhovitskaia, Anna, Schreiner, Silke   +19 more
core   +1 more source

Cochlear progenitor number is controlled through mesenchymal FGF receptor signaling

eLife, 2015
The sensory and supporting cells (SCs) of the organ of Corti are derived from a limited number of progenitors. The mechanisms that regulate the number of sensory progenitors are not known.
Sung-Ho Huh, Mark E Warchol, David M Ornitz   +2 more
doaj   +1 more source

Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells [PDF]

Proceedings of the National Academy of Sciences, 2001
Edited by Louis J. Ignarro, University of California, Los Angeles School of Medicine, Los Angeles, CA, and approved August 27, 2001 (received for review May 16, 2001)
L A, Birder, A J, Kanai, W C, de Groat, S, Kiss, M L, Nealen, N E, Burke, K E, Dineley, S, Watkins, I J, Reynolds, M J, Caterina   +9 more
openaire   +2 more sources

Human Mas-related G protein-coupled receptors-X1 induce chemokine receptor 2 expression in rat dorsal root ganglia neurons and release of chemokine ligand 2 from the human LAD-2 mast cell line [PDF]

, 2013
Primate-specific Mas-related G protein-coupled receptors-X1 (MRGPR-X1) are highly enriched in dorsal root ganglia (DRG) neurons and induce acute pain. Herein, we analyzed effects of MRGPR-X1 on serum response factors (SRF) or nuclear factors of activated
Kathrin Rothe (386395), Ingrid Boekhoff, Ingrid Boekhoff (180345), Andreas Breit (180329), Solinski Hans Jürgen, Petermann, Franziska, Andreas Breit, Hans Jürgen Solinski (166922), Rothe Kathrin, Thomas Gudermann, Franziska Petermann, Boekhoff, Ingrid, Breit, Andreas, Boekhoff Ingrid, Rothe, Kathrin, Gudermann, Thomas, Gudermann Thomas, Breit Andreas, Thomas Gudermann (77426), Hans Jürgen Solinski, Petermann Franziska, Franziska Petermann (220017), Solinski, Hans Jürgen, Kathrin Rothe   +23 more
core   +1 more source

Sensory nerves enhance triple-negative breast cancer invasion and metastasis via the axon guidance molecule PlexinB3

npj Breast Cancer, 2022
In breast cancer, nerve presence has been correlated with more invasive disease and worse prognosis, yet the mechanisms by which different types of peripheral nerves drive tumor progression remain poorly understood.
Thanh T. Le, Samantha L. Payne, Maia N. Buckwald, Lily A. Hayes, Savannah R. Parker, Christopher B. Burge, Madeleine J. Oudin   +6 more
doaj   +1 more source