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Background The nasal cavity of all vertebrates houses multiple chemosensors, either innervated by the Ist (olfactory) or the Vth (trigeminal) cranial nerve. Various types of receptor cells are present, either segregated in different compartments (e.g. in
Hansen Anne
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Carcinogenesis and Metastasis: Focus on TRPV1-Positive Neurons and Immune Cells
Both sensory neurons and immune cells, albeit at markedly different levels, express the vanilloid (capsaicin) receptor, Transient Receptor Potential, Vanilloid-1 (TRPV1).
Nuray Erin, Arpad Szallasi
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Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells [PDF]
Neuropilin (NRP) receptors and their class 3 semaphorin (SEMA3) ligands play well-established roles in axon guidance, with loss of NRP1, NRP2, SEMA3A or SEMA3F causing defasciculation and errors in growth cone guidance of peripherally projecting nerves ...
Howard, Beatrice +19 more
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Intrinsic frequency response patterns in mechano-sensory neurons of the leech
Animals employ mechano-sensory systems to detect and explore their environment. Mechano-sensation encompasses stimuli such as constant pressure, surface movement or vibrations at various intensities that need to be segregated in the central nervous ...
Linda Fischer +3 more
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Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons [PDF]
Signaling by brain-derived neurotrophic factor (BDNF) via the TrkB receptor, or by neurotrophin-3 (NT3) through the TrkC receptor support distinct populations of sensory neurons.
Schimmang, Thomas +26 more
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Mouse embryonic stem cells as a discovery tool in neurobiology [PDF]
Mouse ES cells can recapitulate, under suitable tissue culture conditions, early events in neurogenesis. As wildtype or genetically modified ES cells can be grown in unlimited quantities, their differentiation into neurons represents an attractive model
Nikoletopoulou, Vassiliki
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Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells.
Receptors implicated in cough hypersensitivity are transient receptor potential vanilloid 1 (TRPV1), transient receptor potential cation channel, Subfamily A, Member 1 (TRPA1) and acid sensing ion channel receptor 3 (ASIC3).
Shadia Omar +10 more
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Sensory Mechanisms in Mammalian Touch Receptor Cells [PDF]
The sense of touch is critical for hand dexterity that allows mammals to recognize and grasp objects. Different qualities of touch are encoded by sensory neurons with distinct properties. Shapes and curvature are encoded by Merkel cell-neurite complexes, which mediate slowly adapting type I (SAI) responses. Merkel cells, which cluster in fingertips and
openaire +1 more source
Tachykinins stimulate a subset of mouse taste cells. [PDF]
The tachykinins substance P (SP) and neurokinin A (NKA) are present in nociceptive sensory fibers expressing transient receptor potential cation channel, subfamily V, member 1 (TRPV1).
Jeff Grant
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Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells [PDF]
Edited by Louis J. Ignarro, University of California, Los Angeles School of Medicine, Los Angeles, CA, and approved August 27, 2001 (received for review May 16, 2001)
L A, Birder +9 more
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