Results 231 to 240 of about 117,705 (306)

Low fT3/fT4 ratio as a proxy for muscle wasting in patients with advanced non-small cell lung cancer treated with pembrolizumab. [PDF]

Front Oncol
Eccher S, Sposito M, Trestini I, Scaglione IM, Pasqualin L, Tregnago D, Avancini A, Insolda J, Confortini L, Dodi A, Stefani A, Cintoni M, Sperduti I, Mele MC, Loupakis F, Tiseo M, Bria E, Milella M, Pilotto S, Belluomini L.   +19 more
europepmc   +1 more source

Creating Cell‐Based Hybrid Noodles for Sustainable and Nutrient‐Balanced Diets via a Serum‐Free and Animal‐Free 3D Co‐Differentiation System

Advanced Science, EarlyView.
This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan, Luyi Wang, Wanqiang Sun, Yiwei Feng, Dandan Wang, Haohao Tang, Zhenwu Ma, Guocheng Du, Jian Chen, Jingwen Zhou   +9 more
wiley   +1 more source

Muscle wasting and the response to exercise in lung-injured mice is not primarily driven through the glucocorticoid axis. [PDF]

Am J Physiol Endocrinol Metab
Chuang Key CC, Belfield L, Krall JTW, Gibbs KW, Liu C, Purcell L, Stapleton RD, Poynter ME, Toth MJ, Quinn M, Das SK, Files DC.   +11 more
europepmc   +1 more source

Guidelines For Community Based Nutrition Rehabilitation [PDF]

, 1987
Kimboka, S., Macha, E., Manyama, B., Mnubi, E., Ntoga, B.   +4 more
core  

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Ghrelin ameliorates sepsis-induced acute skeletal muscle wasting via hypothalamic JAK2/STAT3-AgRP pathway. [PDF]

Int J Surg
Duan K, Li D, Chen T, Li W, Sun X, Gu L, Wang P, Gao X, Zhou J.   +8 more
europepmc   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Disease entity impacts muscle wasting in the ICU with COVID-19 patients losing muscle nearly twice as fast. [PDF]

Sci Rep
Kolck J, Hosse C, Fehrenbach U, Beetz NL, Auer TA, Pille C, Geisel D.   +6 more
europepmc   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Enobosarm in Muscle Wasting

JCSM Communications
Stephan vonHaehling
doaj   +1 more source