Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Complete Upper Body Bar Enhances Strength Training During Bench Press
Barbell (BB) and dumbbell (DB) devices are commonly used during a bench press to develop the muscles of the chest, shoulders, and upper arms. Recently, a complete upper body bar (CUBB) was designed to train the muscles of the forearm by allowing for ...
He Wang +6 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
The Muscle Cells in Pelvic Floor Dysfunctions: Systematic Review
Background/Aims: The pelvic floor muscles are important structures involved in pelvic floor tone, pelvic organ support, and continence. The aim of this study was to perform an update on the pelvic floor muscle structure and function alterations of women ...
Ana Margarida Vieira +3 more
doaj +1 more source
Aging and Muscle Fatigability in the Upper Extremity [PDF]
Aging is accompanied by reductions in strength and contraction velocity, and increased fatigability of limb muscles during high-velocity dynamic contractions.
Kuplic, Andrew
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Muscle Endurance Training in a Person with Friedreich’s Ataxia
Friedreich’s ataxia (FRDA) results from a faulty mitochondrial protein known as Frataxin. The purpose of this case report was to test whether skeletal muscle in FRDA can adapt to an endurance-based training program using neuromuscular electrical ...
Nicole T. McGarrell +2 more
doaj +1 more source
Research Progress of Traditional Chinese Medicine Formula Yiqi and Muscle Building Decoction and Carcinogenic Sarcopenia [PDF]
Jianhua Ke
openalex +1 more source
The Organization and Role During Locomotion of the Proximal Musculature of the Cricket Foreleg : I. Anatomy and Innervation [PDF]
The structure of the proximal segments of the cricket (Gryllus bimaculatus) foreleg, together with the associated musculature and its innervation are described.
Laurent, Gilles, Richard, Daniel
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

