Results 61 to 70 of about 3,255,580 (393)
Primary osteoporosis (POP), which is caused by unbalanced bone remodeling, leads to significant economic and societal burdens globally. Gushukang (GSK) granule serves as one commonly used prescription for POP in Traditional Chinese Medicine (TCM).
Qiang Wang+11 more
doaj
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Barefoot and shod running: their effects on foot muscle kinetics [PDF]
Running shoe technology has advanced significantly in the last 50 years, although the overall injury rate has yet to decrease. Barefoot (BF) running has become increasing more popular in the last 10 years.
Sinclair, Jonathan Kenneth
core
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
Effects of Caffeine Supplementation on the Recovery of Professional Soccer Players
(1) Introduction: Soccer players face high demand for training and games. To facilitate their performance, many studies have investigated ergogenic supplements that can assist in the recovery and performance of players.
Thais Marques e Silva+3 more
doaj +1 more source
The correlation between wing kinematics and steering muscle activity in the blowfly Calliphora vicina [PDF]
Determining how the motor patterns of the nervous system are converted into the mechanical and behavioral output of the body is a central goal in the study of locomotion.
Balint, Claire N., Dickinson, Michael H.
core
Muscle Development: Making Drosophila muscle [PDF]
Analysis of flies with mutations in the gene encoding the D-mef2 transcription factor identifies it as a controller of differentiation in multiple muscle cell types; it is the first such gene to be described.
openaire +3 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Loop Diuretics and Sarcopenia: A Potential Association
Background: Loop diuretics (LDs) are used to treat various health conditions including heart failure (HF), liver cirrhosis, and chronic kidney disease (CKD).
Nikolaos D. Karakousis+1 more
doaj +1 more source
Restoration of grasp following paralysis through brain-controlled stimulation of muscles
Patients with spinal cord injury lack the connections between brain and spinal cord circuits that are essential for voluntary movement. Clinical systems that achieve muscle contraction through functional electrical stimulation (FES) have proven to be ...
C. Ethier+3 more
semanticscholar +1 more source