Results 131 to 140 of about 147,437 (336)
, 2012 Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by degeneration of alpha motor neurons resulting in hypotonia, progressive muscular weakness and atrophy.30 Spinal muscular atrophy is one of the leading hereditary causes of infant mortality,31 it comprises the second most common fatal progressive diseases after cystic fibrosis.28
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ERB'S PRIMARY MUSCULAR ATROPHY. [PDF]
JAMA: The Journal of the American Medical Association, 1896 Since Duchenne first described progressive muscular atrophy in adults and infants and regraded each form as of peripheral origin, the study of the clinical history and pathology of muscular dystrophies has only partially decided which are of muscular and which of spinal origin. We now believe that the hereditary form found during infancy and early life,
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Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
Advanced Healthcare Materials, EarlyView.This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis +6 more
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Biomarkers in spinal muscular atrophy
Frontiers in NeurologySpinal muscular atrophy is a hereditary disorder leading to severe neuromuscular impairment. With the introduction of disease-modifying therapies in recent years, the role of biomarkers has expanded from aiding diagnosis to monitoring treatment responses,
Liping Yan +3 more
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Advanced Healthcare Materials, EarlyView.This study investigates a synergistic effect between 3D‐printed surface features and mechanical micro‐strain in enhancing the osteogenic, angiogenic, and myogenic responses of human mesenchymal stem cells (hMSCs). Load‐induced mechanotransduction, facilitated by the implant's architectural design, significantly amplifies hMSC differentiation.
Se‐Hwan Lee +9 more
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ON BULBAR PARALYSIS FOLLOWED BY PROGRESSIVE MUSCULAR ATROPHY, TREATED BY A NEW METHOD OF IONIC MEDICATION (STATIC IONIZATION) [PDF]
, 1908 John Fletcher Little, T. J. Bokenham
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Structural changes of lumbar muscles in non-specific low back pain [PDF]
, 2016 Background: Lumbar muscle dysfunction due to pain might be related to altered lumbar muscle structure. Macroscopically, muscle degeneration in low back pain (LBP) is characterized by a decrease in cross-sectional area and an increase in fat infiltration ...
Danneels, Lieven +3 more
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Advanced Healthcare Materials, EarlyView.This study develops 3D‐printed Mg‐MC/PLGA scaffolds with varying Mg concentrations (0–20%). The 5% Mg scaffold shows optimal cytocompatibility, osteogenic activity in vitro, and significantly enhances bone regeneration in rabbits, improving bone volume and mechanical strength.
Shihang Liu +9 more
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A CASE OF NEURITIS SIMULATING PROGRESSIVE MUSCULAR ATROPHY ASSOCIATED WITH NYSTAGMUS AND INCREASED KNEE JERKS. [PDF]
, 1894 HAROLD N. MOYER
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