Results 151 to 160 of about 134,576 (312)

Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. [PDF]

, 2014
Macroautophagy (hereafter autophagy) is a key pathway in neurodegeneration. Despite protective actions, autophagy may contribute to neuron demise when dysregulated.
Batlevi, Yakup, Carromeu, Cassiano, Cortes, Constanza J, Frankowski, Harald, Garden, Gwenn A, Ivanov, Nishi, La Spada, Albert R, Le, Amy, Miranda, Helen C, Muotri, Alysson R, Sopher, Bryce L, Young, Jessica E   +11 more
core  

Recent Advances of Graphene‐Based Wearable Sensors: Synthesis, Fabrication, Performance, and Application in Smart Device

Advanced Materials Interfaces, EarlyView.
This review article explores applications in wearable sensors such as mechanical, electrophysiological, and gas sensors, highlighting advancements that improve device performance and predictability. In addition to analyzing graphene's synthesis techniques, including traditional and advanced laser‐based methods, the article discusses fabrication ...
Fatemeh Saeedi, Reza Ansari, Mojtaba Haghgoo   +2 more
wiley   +1 more source

Riemannian tangent space mapping and elastic net regularization for cost-effective EEG markers of brain atrophy in Alzheimer's disease [PDF]

arXiv, 2017
The diagnosis of Alzheimer's disease (AD) in routine clinical practice is most commonly based on subjective clinical interpretations. Quantitative electroencephalography (QEEG) measures have been shown to reflect neurodegenerative processes in AD and might qualify as affordable and thereby widely available markers to facilitate the objectivization of ...
arxiv  

4D Bioprinted Self‐Folding Scaffolds Enhance Cartilage Formation in the Engineering of Trachea

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A bilayer self‐folding scaffold, triggerable by humidity, is fabricated via 4D bioprinting for trachea engineering. An analytical model is derived to predict its radius of curvature, enabling its scalability. Cartilage progenitor cells seeded on the scaffold perceive scaffold final curvature and react to it, by enhancing the upregulation of pro ...
Irene Chiesa, Alessio Esposito, Giovanni Vozzi, Riccardo Gottardi, Carmelo De Maria   +4 more
wiley   +1 more source

Microfluidic Spinning of PEDOT:PSS Microfibers for Nerve Guidance Conduits

Advanced Materials Technologies, EarlyView.
This publication explores the fabrication of microfluidically spun PEDOT:PSS microfibers for conductive nerve guidance conduits (NGCs). It details the spinning process, fiber characterization, and biocompatibility assessment. The study highlights the fibers' mechanical and electrical properties, non‐cytotoxicity, and potential for nerve regeneration or
Matthias Geiger, Judith Frank, Felix Schmitz, Richard Paul, Sebastian Bernhard Rauer, Stanislav Koulchitsky, Angelika Lampert, John Linkhorst, Matthias Wessling   +8 more
wiley   +1 more source

Exploring 3D Printing and Electrospinning Technologies for Advanced Porous Membrane Fabrication: A Review

Advanced Materials Technologies, EarlyView.
This paper contrasts electrospinning and 3D printing for porous membrane fabrication, evaluating their evolution, cost, resolution, mechanical traits, and scalability. While 3D printing excels in material diversity and industrial adaptability, electrospinning achieves finer resolution and thermal resilience.
Eya Kacem, Han Dong Suk, Deepalekshmi Ponnamma, Mohamed K Hassan, Alaa Hawari, Basheer A. Alshammari, Maryam Al‐Ejji   +6 more
wiley   +1 more source

Development of Photo‐Biocatalytic Redox System for Asymmetric Synthesis of Optically Active Amines Using Blue Light and Transaminases. A Case Study Toward Mavacamten

Advanced Synthesis &Catalysis, EarlyView.
Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos, Aleksandra Rudzka, Anna Hoser, Tamara Reiter, Wolfgang Kroutil, Paweł Borowiecki   +5 more
wiley   +1 more source

Clinical decision making around commercial use of gene and genetic therapies for spinal muscular atrophy

Neurotherapeutics
Spinal muscular atrophy is no longer a leading cause of inherited infant death in the United States. Since 2016, three genetic therapies have been approved for the treatment of spinal muscular atrophy.
Megan A. Waldrop
doaj  

تجربیات زیسته یک مادر دارای کودک مبتلا به سندرم وردینگ هافمن: مطالعه موردی کیفی The Lived Experiences of the Mother of a Child with Werdnig-Hoffman Syndrome: A Qualitative Case Study [PDF]

, 2016
مقدمه: سندوم وردینگ هافمن جزء بیماری‌های تحلیل برنده و پیش‌رونده عصبی- نخاعی محسوب می‌شود که به صورت اتوزومی نهفته به ارث می ...
Araghian-Mojarad, F., Jouybari, L., Sanagoo, A.   +2 more
core  

Recycling and Sustainable Design for Smart Textiles − A Review

Advanced Sustainable Systems, EarlyView.
The article reviews recycling strategies and sustainable design approaches for smart textiles, emphasizing eco‐friendly materials, mechanical and chemical recycling methods, and circular economy principles. It explores challenges in separating embedded electronics and highlights recent innovations in sustainable textile technology.
Melkie Getnet Tadesse, Molla Tadesse Abate, Jörn Felix Lübben, Michael Rauch   +3 more
wiley   +1 more source