Results 151 to 160 of about 604,348 (394)

Proximal spinal muscular atrophy 5q

open access: yesНервно-мышечные болезни, 2020
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article Editorial
doaj  

Financial cost and quality of life of patients with spinal muscular atrophy identified by symptoms or newborn screening

open access: yesDevelopmental Medicine & Child Neurology, 2022
T. Dangouloff   +6 more
semanticscholar   +1 more source

Neurofilament as a potential biomarker for spinal muscular atrophy

open access: yesAnnals of Clinical and Translational Neurology, 2019
To evaluate plasma phosphorylated neurofilament heavy chain (pNF‐H) as a biomarker in spinal muscular atrophy (SMA).
B. Darras   +16 more
semanticscholar   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin   +14 more
wiley   +1 more source

Microscopically Adaptable Bioink Guide Cell Compartmentalization toward Morphogenesis of a Functional Vasculature‐Like System

open access: yesAdvanced Healthcare Materials, EarlyView.
Contractile vasculatures are fabricated through a one‐step bioprinting strategy. The adaptable microenvironment provided by ECM‐mimicking bioink triggers cell sorting and compartmentalization of endothelial cells and vascular smooth muscle cells toward a histological configuration by focal adhesion kinase‐mediated upregulation of cell adhesion and ...
Jun Chen   +9 more
wiley   +1 more source

Spinal Muscular Atrophy [PDF]

open access: yes, 2012
Spinal muscular atrophy (SMA) is a neuromuscular disorder characterized by degeneration of alpha motor neurons resulting in hypotonia, progressive muscular weakness and atrophy.30 Spinal muscular atrophy is one of the leading hereditary causes of infant mortality,31 it comprises the second most common fatal progressive diseases after cystic fibrosis.28
openaire   +3 more sources

Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses

open access: yesAdvanced Healthcare Materials, EarlyView.
Granular hydrogels are now emerging as promising biomaterials due to their inherent microporousity, injectability, and modularity. They have shown improvements in cell viability and migration, cellular/tissue infiltration, host tissue integration, mitigated foreign body response, and tissue regeneration.
Asmasadat Vaziri   +6 more
wiley   +1 more source

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