Results 201 to 210 of about 147,437 (336)

The Physiological Consequences of Bed Rest

, 2007
Bed rest often is used to treat a wide variety of medical conditions. However, bed rest results in profound deconditioning of the body. Bed rest reduces the hydrostatic pressure gradient within the cardiovascular system, reduces muscle force production,
Drury, Daniel G., Stuempfle, Kristin J.
core  

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Dysregulated synaptic gene expression in oligodendrocytes of spinal and bulbar muscular atrophy. [PDF]

JCI Insight
Iida M, Sahashi K, Hirunagi T, Sakakibara K, Maeda K, Iguchi Y, Li J, Ogura Y, Iizuka M, Akashi T, Hinohara K, Sugio S, Wake H, Nakatochi M, Katsuno M.   +14 more
europepmc   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Analysis of Eye Movements in Adults with Spinal Muscular Atrophy. [PDF]

Medicina (Kaunas)
Krivošík M, Košutzká Z, Šaling M, Boleková V, Brauneckerová R, Gábor M, Valkovič P.   +6 more
europepmc   +1 more source

Progressive muscular atrophy and posterior dislocation of the humerus following electric shock [PDF]

, 1984
D A Francis, James Heron
openalex   +1 more source

Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu, Zhihuang Zheng, Marleen Silke Oswald, Guozhe Cheng, Jun Liu, Qidi Zhai, Ute Kruegel, Michael Schaefer, Holger Gerhardt, Nicole Endlich, Maik Gollasch, Stefan Simm, Dmitry Tsvetkov   +12 more
wiley   +1 more source

Ketosis-prone Diabetes as a Presentation of New-onset Diabetes in a Patient With Spinal Muscular Atrophy Type III. [PDF]

JCEM Case Rep
Thewjitcharoen Y, Nakasatien S, Kulkantrakorn K, Himathongkam T.   +3 more
europepmc   +1 more source

THE BENIGN PROXIMAL SPINAL PROGRESSIVE MUSCULAR ATROPHIES

, 1968
Henry A. Peters, John M. Opitz, I Goto, Hans H. Reese   +3 more
openalex   +1 more source

Mitochondrial functions in chronic spinal muscular atrophy. [PDF]

, 1980
J M Gobernado, Mario Gosálvez, Chandler S. Cortina, M Lousa, Catherine Riva, A. Gimeno   +5 more
openalex   +1 more source