Results 231 to 240 of about 604,348 (394)

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

Advanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li, Jinlin Liao, Yuxi Zhang, Zifu Yao, Junxin Huang, Kejia Wu, Lu Li, Yiling Peng, Haili Zhu, Xue Hong, Xi Liu, Lili Zhou, Fan Fan Hou, Haiyan Fu, Youhua Liu   +14 more
wiley   +1 more source

Development of the "SMA NNE," a short neonatal neurological examination for newborns with spinal muscular atrophy. [PDF]

Eur J Pediatr
Mercuri E, Coratti G, Cutrona C, De Sanctis R, Stanca G, Cicala G, Villa M, Capasso A, Arpaia C, Sbarbati M, Krosschell K, Romeo D, Berti B, Finkel R, Pane M.   +14 more
europepmc   +1 more source

Adult onset spinal muscular atrophy with atrophic testes: report of two cases. [PDF]

, 1986
J Richert, Jack P. Antel, John J. Canary, William C. Maxted, Dennis R. Groothuis   +4 more
openalex   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Munc13-1 restoration mitigates presynaptic pathology in spinal muscular atrophy. [PDF]

Nat Commun
Moradi M, Weingart J, Deng C, Nasouti M, Briese M, Jablonka S, Sauer M, Sendtner M.   +7 more
europepmc   +1 more source

Mitochondrial functions in chronic spinal muscular atrophy. [PDF]

, 1980
J M Gobernado, Mario Gosálvez, Chandler S. Cortina, M Lousa, Catherine Riva, A. Gimeno   +5 more
openalex   +1 more source

Enabling the Fabrication of Complex Soft Iontronics Using Multi‐Material 3D Extrusion Printing

Advanced Science, EarlyView.
Using multi‐material 3D printing, ionic diodes and logic circuits are created using only one fabrication technique and are integrated into metamaterial scaffolds with advanced mechanical behavior, paving the way for soft devices with tunable sensitivity to mechanical strain.
Trevor J. Kalkus, Tamara V. Unterreiner, Målin Schmidt, Laura D. Wächter, Christina R. Schmitt, Ankit Mishra, Christine Selhuber‐Unkel   +6 more
wiley   +1 more source

THE BENIGN PROXIMAL SPINAL PROGRESSIVE MUSCULAR ATROPHIES

, 1968
Henry A. Peters, John M. Opitz, I Goto, Hans H. Reese   +3 more
openalex   +1 more source

Progressive muscular atrophy and posterior dislocation of the humerus following electric shock [PDF]

, 1984
D A Francis, James Heron
openalex   +1 more source