Acute Kidney Injury and Quadriparesis Due to Rosuvastatin Induced Rhabdomyolysis- A Case Report [PDF]
Statins as lipid lowering drugs, are safe and effective in reducing cardiovascular disease risk, but rarely produce myopathy like myalgia, myositis or rhabdomyolysis.
KAMLESH S. SUTHAR+2 more
doaj +1 more source
Hereditary myopathy with early respiratory failure in China: one case report and literatures review
Objective To retrospectively analyze the clinical sign and symptom, pathological and genetic characteristics of a case of hereditary myopathy with early respiratory failure (HMERF).
LI Ying+5 more
doaj +1 more source
Control of the Extension-Flexion Cycle of Human Knees During Bicycle Riding by a Synergy of Solitary Muscular Excitations and Contractions [PDF]
A Hill-type model is proposed for the extension-flexion cycle of human knees during bicycle riding. The extension-flexion cycle is controlled by a synergy of muscular excitations and contractions of the knee musculature. Muscular action potentials are modeled by Sine-Gordon kinks, while titin-influenced actomyosin contractionsare modeled by Korteweg-de
arxiv +1 more source
Disease taxonomy - monogenic muscular dystrophy [PDF]
The field of the autosomal recessive progressive muscular dystrophies has clarified significantly following the recent elucidation of the genetic and molecular etiology of a number of these entities. These studies illustrate how genetics provides a rationale and objective basis for a new, refined nosology.
openaire +3 more sources
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
RegistrAME: the Spanish self-reported patient registry of spinal muscular atrophy
Background Spinal Muscular Atrophy (SMA) is a rare neuromuscular disorder characterized by progressive degeneration of motor neurons and muscle weakness resulting in premature death or severe motor disability.
Maria Grazia Cattinari+2 more
doaj +1 more source
Background/AimsClevudine (CLV) has potent antiviral activity against chronic hepatitis B (CHB) virus infection. The long-term efficacy and safety of CLV therapy in na?ve patients with CHB were investigated.Methods : In this retrospective study, 152 na?ve
doaj +1 more source
GaitForeMer: Self-Supervised Pre-Training of Transformers via Human Motion Forecasting for Few-Shot Gait Impairment Severity Estimation [PDF]
Parkinson's disease (PD) is a neurological disorder that has a variety of observable motor-related symptoms such as slow movement, tremor, muscular rigidity, and impaired posture. PD is typically diagnosed by evaluating the severity of motor impairments according to scoring systems such as the Movement Disorder Society Unified Parkinson's Disease ...
arxiv
Postural control during quiet standing following cervical muscular fatigue: effects of changes in sensory inputs [PDF]
The purpose of the present experiment was to investigate the effects of cervical muscular fatigue on postural control during quiet standing under different conditions of reliability and/or availability of somatosensory inputs from the plantar soles and the ankles and visual information.
arxiv +1 more source
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source