Results 41 to 50 of about 715 (130)

Per‐ and Polyfluoroalkyl Substances and Hand Osteoarthritis: Data From the Osteoarthritis Initiative

open access: yesArthritis &Rheumatology, EarlyView.
Objective To explore whether biologic levels of specific per‐ and polyfluoroalkyl substances (PFAS) and a mixture of PFAS—reflecting the overall effect and accounting for correlations among PFAS—relate to incident hand osteoarthritis (HOA) and progression.
Jeffrey B. Driban   +14 more
wiley   +1 more source

Measuring the Impact: Magnetic Resonance Imaging Response of Sacroiliac Joints to Tumor Necrosis Factor Inhibitors in Youth With Axial Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes (PROs) in youth with axial juvenile spondyloarthritis (axJSpA) initiating tumor necrosis factor inhibitor (TNFi).
Timothy G. Brandon   +8 more
wiley   +1 more source

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

open access: yesArthritis &Rheumatology, EarlyView.
Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and posttranscriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron splicing ...
Luz P. Blanco   +11 more
wiley   +1 more source

Reliability of ultrasonography to detect inflammatory lesions and structural damage in juvenile idiopathic arthritis

open access: yesPediatric Rheumatology Online Journal, 2018
Background Musculoskeletal Ultrasonography (MSUS) is an important tool for the clinical assessment in Juvenile Idiopathic Arthritis (JIA). The objective of this study was to evaluate the reliability of MSUS to detect elementary lesions: synovitis ...
Lucio Ventura-Ríos   +8 more
doaj   +1 more source

Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth. Precocial species, which are ambulatory at birth, develop advanced skeletal maturity in utero and experience postnatal development under mechanical loading.
Christopher J. Panebianco   +8 more
wiley   +1 more source

El Efecto Placebo en el Tratamiento del Dolor Musculoesquelético Cervical: un Ensayo Clínico Aleatorizado

open access: yesClínica y Salud. Investigación Empírica en Psicología, 2019
Se ha estudiado el efecto placebo en el dolor musculoesquelético cervical ampliamente. Se deriva del contexto de la intervención y es común a todas ellas. Las últimas investigaciones apuntan a que Kinesio Taping podría ser una forma de efecto placebo.
Guillermo Ceniza-Bordallo   +2 more
doaj   +1 more source

DOLOR MUSCULOESQUELÉTICO: FIBROMIALGIA Y DOLOR MIOFASCIAL

open access: yesRevista Médica Clínica Las Condes, 2019
Resumen: El dolor musculoesquelético (DME) es una de las causas principales de dolor crónico no oncológico y de discapacidad laboral. Tiene una gran prevalencia y está subdiagnosticado.
Maritza Velasco
doaj   +1 more source

Comparative Evaluation of R134a and HFO‐1234ze Cryogen Spray Cooling Using a Mouse Model With Controllable Epidermal Pigmentation

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Cryogen spray cooling (CSC) is critical for protecting the epidermis during laser dermatologic procedures. The widely used cryogen, R134a, has a high global warming potential (GWP), motivating interest in environmentally favorable alternatives such as HFO‐1234ze.
Wangcun Jia   +13 more
wiley   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

Lesão muscular: fisiopatologia, diagnóstico, tratamento e apresentação clínica Muscle injury: physiopathology, diagnostic, treatment and clinical presentation

open access: yesRevista Brasileira de Ortopedia, 2011
O tecido muscular esquelético possui a maior massa do corpo humano, com 45% do peso total. As lesões musculares podem ser causadas por contusões, estiramentos ou lacerações. A atual classificação separa as lesões entre leve, moderada e grave. Os sinais e
Tiago Lazzaretti Fernandes   +2 more
doaj   +1 more source

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