Results 11 to 20 of about 9,516,409 (390)

Insights into the underlying pathogenesis and therapeutic potential of endoplasmic reticulum stress in degenerative musculoskeletal diseases

Military Medical Research, 2023
Degenerative musculoskeletal diseases are structural and functional failures of the musculoskeletal system, including osteoarthritis, osteoporosis, intervertebral disc degeneration (IVDD), and sarcopenia.
Ze-Qin Wen, Jun Lin, Wen-Qing Xie, Yun-Han Shan, Ge-Hua Zhen, Yu-Sheng Li   +5 more
doaj   +2 more sources

2022 American College of Rheumatology Guideline for Vaccinations in Patients With Rheumatic and Musculoskeletal Diseases

Arthritis care & research, 2023
To provide evidence‐based recommendations on the use of vaccinations in children and adults with rheumatic and musculoskeletal diseases (RMDs).
A. Bass, E. Chakravarty, E. Akl, Clifton O. Bingham, L. Calabrese, L. Cappelli, S. Johnson, L. Imundo, K. Winthrop, R. Arasaratnam, Lindsey R. Baden, R. Berard, S. Bridges, Jonathan T. L. Cheah, J. R. Curtis, Polly J. Ferguson, I. Hakkarinen, K. Onel, Grayson Schultz, V. Sivaraman, Benjamin J. Smith, J. Sparks, Tiphanie P Vogel, E. Williams, C. Calabrese, Joanne S. Cunha, J. Fontanarosa, M. Gillispie‐Taylor, E. Gkrouzman, Priyanka Iyer, K. Lakin, A. Legge, Mindy S. Lo, M. M. Lockwood, R. Sadun, Namrata Singh, Nancy M. Sullivan, H. Tam, Marat Turgunbaev, Amy S. Turner, J. Reston   +40 more
semanticscholar   +2 more sources

Cellular Senescence: The Driving Force of Musculoskeletal Diseases. [PDF]

Biomedicines
The aging of the world population is closely associated with an increased prevalence of musculoskeletal disorders, such as osteoporosis, sarcopenia, and osteoarthritis, due to common genetic, endocrine, and mechanical risk factors.
Falvino A, Gasperini B, Cariati I, Bonanni R, Chiavoghilefu A, Gasbarra E, Botta A, Tancredi V, Tarantino U.   +8 more
europepmc   +2 more sources

Cell-Based Therapies for Degenerative Musculoskeletal Diseases. [PDF]

Adv Sci (Weinh), 2023
Degenerative musculoskeletal diseases (DMDs), including osteoporosis, osteoarthritis, degenerative disc disease, and sarcopenia, present major challenges in the aging population.
Yin P, Jiang Y, Jiang Y, Fang X, Wang D, Li Y, Chen M, Deng H, Tang P, Zhang L.   +9 more
europepmc   +2 more sources

Post-Acute COVID-19 Joint Pain and New Onset of Rheumatic Musculoskeletal Diseases: A Systematic Review

Diagnostics, 2023
As the number of reports of post-acute COVID-19 musculoskeletal manifestations is rapidly rising, it is important to summarize the current available literature in order to shed light on this new and not fully understood phenomenon.
J. Ciaffi, E. Vanni, L. Mancarella, V. Brusi, L. Lisi, F. Pignatti, S. Naldi, E. Assirelli, Simona Neri, M. Reta, C. Faldini, Francesco Ursini   +11 more
semanticscholar   +1 more source

2023 EULAR recommendations for the management of fatigue in people with inflammatory rheumatic and musculoskeletal diseases

Annals of the Rheumatic Diseases, 2023
Objectives Fatigue is prevalent in people with inflammatory rheumatic and musculoskeletal diseases (I-RMDs) and recognised as one of the most challenging symptoms to manage.
E. Dures, B. Farisoğulları, E. Santos, A. Moltó, C. Feldthusen, Claire Harris, C. Elling-Audersch, Deirdre Connolly, E. Elefante, F. Estévez-López, I. Bini, J. Primdahl, Kirsten Hoeper, Marie Urban, M. A. van de Laar, M. Redondo, Peter Böhm, R. Amarnani, Rhys J Hayward, R. Geenen, Simona Rednic, Susanne Pettersson, T. Thomsen, Till Uhlig, Valentin Ritschl, P. Machado   +25 more
semanticscholar   +1 more source

Novel insights into the METTL3-METTL14 complex in musculoskeletal diseases

Cell Death Discovery, 2023
N6-methyladenosine (m^6A) modification, catalyzed by methyltransferase complexes (MTCs), plays many roles in multifaceted biological activities. As the most important subunit of MTCs, the METTL3-METTL14 complex is reported to be the initial factor that ...
Yeqiu Xu, Yuanzhuang Zhang, Yinzhou Luo, Guanzhen Qiu, Jie Lu, M. He, Yong Wang   +6 more
semanticscholar   +1 more source

Current insights into the functional roles of ferroptosis in musculoskeletal diseases and therapeutic implications

Frontiers in Cell and Developmental Biology, 2023
Ferroptosis is a novel type of cell death associated with iron accumulation and excessive lipid peroxidation. Elucidating the underlying molecular mechanisms of ferroptosis is intensively related to the development and treatment of multiple diseases ...
Fan Zhang, Yuanliang Yan, Yuan Cai, Qiuju Liang, Yuan-Liang Liu, Bi Peng, Zhijie Xu, Wei Liu   +7 more
semanticscholar   +1 more source

EULAR recommendations for cardiovascular risk management in rheumatic and musculoskeletal diseases, including systemic lupus erythematosus and antiphospholipid syndrome

Annals of the Rheumatic Diseases, 2022
Objective To develop recommendations for cardiovascular risk (CVR) management in gout, vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD), Sjögren’s syndrome (SS), systemic lupus erythematosus (SLE) and ...
G. Drosos, D. Vedder, E. Houben, L. Boekel, F. Atzeni, S. Badreh, D. Boumpas, N. Brodin, I. Bruce, M. González-Gay, S. Jacobsen, G. Kerekes, F. Marchiori, C. Mukhtyar, M. Ramos-Casals, N. Sattar, K. Schreiber, S. Sciascia, E. Svenungsson, Z. Szekanecz, A. Tausche, A. Tyndall, V. van Halm, A. Voskuyl, G. Macfarlane, M. Ward, M. Nurmohamed, Maria G. Tektonidou   +27 more
semanticscholar   +1 more source

The Potential Roles of Ferroptosis in Pathophysiology and Treatment of Musculoskeletal Diseases—Opportunities, Challenges, and Perspectives

Journal of Clinical Medicine, 2023
Ferroptosis is different from other forms of cell death, such as apoptosis, autophagy, pyroptosis, and cuproptosis, mainly involving iron metabolism and lipid peroxidation. Ferroptosis plays an important role in various disease, such as malignant tumors,
Yunxiang Hu, Yufei Wang, Sanmao Liu, Hong Wang   +3 more
semanticscholar   +1 more source