Results 141 to 150 of about 18,542,654 (255)

Piezo1-mediated Mechanotransduction in the musculoskeletal system: Signaling networks and therapeutic perspectives. [PDF]

Bone Rep
Zhao H, Huang J, Tan Y, Shen S, Ying Z, Li Z, Xiong Y, Ge H, Wang X, Zhan H, Shen Y, Du G.   +11 more
europepmc   +1 more source

Robotic Assistants in the Operating Room: A Systematic Review of Vision‐Based Systems for Nonoperative Tasks

Advanced Robotics Research, EarlyView.
This review brings together 20 publications describing 11 robotic system families developed for instrument handling, sterile‐package opening, supply delivery, and operating room logistics. Perception is becoming more capable through deep learning and language‐guided control, but autonomy remains limited, evidence is largely laboratory‐based, and no ...
Eugenia Mawuenya Akpo, Pietro Falco, Nicholas Raison, Christos Bergeles, Letizia Gionfrida   +4 more
wiley   +1 more source

Sex Hormones & Exercise in the Musculoskeletal System: From Signaling to Structure and Function. [PDF]

Endocr Rev
Colicchio CJ, Hernandez PA, Robinson JL, Connizzo BK.   +3 more
europepmc   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Characteristics of dermal fibroblasts and their biotherapeutic value in musculoskeletal system diseases. [PDF]

Front Bioeng Biotechnol
Zhou L, Zhang Q, Yang H, Zhang G, Fan M, Jin R, Zhou S.   +6 more
europepmc   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Diffusion-Weighted Imaging in the Musculoskeletal System: Evolving Role in Modern Imaging Practice. [PDF]

Diagnostics (Basel)
Tandon A, Bindhumadhavan G.
europepmc   +1 more source

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

Recurrently Activated Baastrup Phenomenon with Consequently Limited Movement at L3/L4 and L4/L5: A Case Report

Brain and Spine
R. Bartha, M. Kleinschmidt, S. Radzanowski   +2 more
doaj   +1 more source

[¹⁸F]-FDG-PET for the assessment of major infectious disorders of the musculoskeletal system. [PDF]

Am J Nucl Med Mol Imaging
Gandhi OH, Gujral J, Amanullah AA, Suyal P, Singh SB, Patil S, Lee W, Bhandari S, Singh CB, Werner TJ, Basu S, Revheim ME, Alavi A.   +12 more
europepmc   +1 more source