Results 141 to 150 of about 504,957 (283)

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo, Dohyeon Kim, Junhyuk Song, Sun‐Young Kim, Youngju Son, Afia Tasnim Rahman, Sangyong Jon   +6 more
wiley   +1 more source

3D Large‐Scale Subwavelength‐Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta‐Array

Advanced Science, EarlyView.
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang, Zi‐Bin Lin, Zhuo Chen, Zhao‐Hui Liu, Jin‐Lian He, Jun‐Jie Song, Long‐Sheng Zeng, Liang Zhou, Ming‐Yue Ding, Yu‐Gui Peng, Ming Yuchi, Xue‐Feng Zhu   +11 more
wiley   +1 more source

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

Advanced Science, EarlyView.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo, Zhiqing Zhao, Wei Wang, Jianfang Niu, Bing Wang, Yunfei Lin, Wei Guo, Taiqiang Yan   +7 more
wiley   +1 more source

The Beneficial Effects of Marine Plant-Derived Compounds on the Musculoskeletal System. [PDF]

Int J Mol Sci
Szabó L, Gere Á, Kovács ZM, Bazsó T, Dienes B.   +4 more
europepmc   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Research progress on sarcopenia in the musculoskeletal system. [PDF]

Bone Res
Mao X, Lv K, Qi W, Cheng W, Li T, Sun Y, Jin H, Pan H, Wang D.   +8 more
europepmc   +1 more source

The role of purinergic signalling in the musculoskeletal system [PDF]

Abbracchio, Agrawal, Alvarenga, Armstrong, Banachewicz, Berenbaum, Biswas, Biver, Bonewald, Bowler, Bowler, Bowler, Brandao-Burch, Brown, Buckley, Buckley, Buckley, Bulman, Burnstock, Burnstock, Burnstock, Burnstock, Buscher, Buvinic, Campo, Carroll, Caswell, Caswell, Chenu, Cheung, Choi, Chowdhury, Costa, Costessi, Croucher, Deli, Dixon, Evans, Ferrari, Fleisch, Fleisch, Fodor, Gartland, Gartland, Gartland, Gartland, Gartland, Genetos, Genetos, Gharibi, Gharibi, Graff, Graff, Grol, Hajjawi, Hayton, Hazama, He, Hecht, Hessle, Hiken, Hoebertz, Hoebertz, Hoebertz, Hollopeter, Hsu, Hung, Huo, Husted, Ihara, Isabel R. Orriss, Jande, Janssens, Janssens, Johnson, Jones, Jorgensen, Jorgensen, Jorgensen, Kanabe, Kaplan, Kaplan, Kara, Kara, Katz, Katz, Ke, Keresztes, Knight, Kono, Koolpe, Koolpe, Korcok, Korcok, Kringelbach, Kudirka, Kumagai, Kumagai, Lee, Leong, Leong, Lerner, Lerner, Li, Li, Liu, Mackenzie, Martinello, Masin, Mediero, Mediero, Meyer, Millward-Sadler, Morrison, Mortensen, Naemsch, Naemsch, Nakamura, Nicke, Nishii, Noronha-Matos, Noronha-Matos, Ohlendorff, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Orriss, Panupinthu, Panupinthu, Pellegatti, Penolazzi, Pines, Ralevic, Reimer, Riddle, Romanello, Romanello, Rosenthal, Rumney, Ryan, Ryten, Schoenberg, Sciancalepore, Shimegi, Sistare, Su, Suzuki, Syberg, Syberg, Takedachi, Tesch, Thompson, Tu, Varani, Varani, Vincenzi, Voss, Wang, Wang, Wang, Weidema, Weidema, Wesselius, Wesselius, Wesselius, Wiebe, Wildman, You, Yu, Yu, Zimmermann, Zippel   +176 more
core   +1 more source

Musculoskeletal problems and backpack carriage among students in Nigeria [PDF]

, 2020
Abaraogu, U.O., Duru, D.O., Ezenwankwo, E.F., Fawole, H., Imaji, B.   +4 more
core   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Musculoskeletal system

The Journal of Physical Fitness and Sports Medicine
  +6 more sources