Results 141 to 150 of about 28,635 (297)
, 2010 Insertional mutagenesis (IM) screens in genetically engineered mouse models of cancer are a powerful tool to identify genes or regions in the genome contributing to tumorigenesis. Current methods to identify the integration sites are not quantitative and
Marco J. Koudijs +9 more
core +1 more source
From wild to tamed: Reimagining novel crops through omics and local plant diversity
PLANTS, PEOPLE, PLANET, EarlyView.The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá +1 more
wiley +1 more source
Insertional Mutagenesis: lessons from Arabidopsis, gaining experience in rice
, 2005 Insertional mutagenesis is a means of analyzing the function of genes through their disruption by foreign DNA followed by observation of the effect on phenotype.
Guiderdoni, Emmanuel +4 more
core
Tn7-Based Genome-Wide Random Insertional Mutagenesis of Candida glabrata
, 2003 We describe and characterize a method for insertional mutagenesis of the yeast pathogen Candida glabrata using the bacterial transposon Tn7. Tn7 was used to mutagenize a C. glabrata genomic fosmid library.
Biery, Matthew C. +8 more
core +1 more source
Pest Management Science, EarlyView.As little as 1–10% of the population is needed to be resistant for demethylation inhibitor fungicides to be rendered ineffective. Following a single round of selection, the frequency increases by more than 15% with limited fitness penalty detected when no selection is present.
Alec J McCallum +5 more
wiley +1 more source
Pest Management Science, EarlyView.A TETRA‐primer amplification refractory mutation system polymerase chain reaction (T‐ARMS‐PCR) method was developed for simultaneous detection of the L412F/V and G408V mutations. L412F/V mutants were created using the CRISPR/Cas tool and no fitness cost was observed.
Georgios Sofianos +3 more
wiley +1 more source
Bt agave: why it is time to explore a new biotechnological frontier
Pest Management Science, EarlyView.Drylands cover 41% of Earth, requiring sustainable crops. Agave, drought‐ and heat‐adapted, offers high‐value products with low water needs. Pests limit yield, yet Bacillus thuringiensis (Bt) Cry proteins, successful in other plants, remain unexploited in Agave.
Aline Vitória Corim Marim +3 more
wiley +1 more source
Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
Phytotherapy Research, EarlyView.ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
Small, EarlyView.Cationic lipopeptides self‐assemble into stable, cell‐like vesicles that merge peptide programmability with lipid self‐organization. These biocompatible compartments efficiently sequester and deliver nucleic acids, enabling high transfection efficiency with low‐toxicity in both HEK293T cells and mesenchymal stem cells (MSCs).
Federica A. Souto‐Trinei +4 more
wiley +1 more source