Results 191 to 200 of about 56,155 (258)

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, Volume 46, Issue 6, Page 1987-2002, June 2026.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

The legacy of Bruce Ames and mitochondrial DNA mutagenicity: integrating oxidative stress, aging, and modern perspectives. [PDF]

Front Mol Biosci
Dang J, Liou JY, Mullah R, Giulivi C.
europepmc   +1 more source

Colorectal Precancerous Lesions: Molecular Mechanisms, Research Tools, and Natural Product‐Based Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu, Chujuan Cui, Lingdong Kong, Qiang Xu, Haibo Cheng, Lisha Zhou, Yang Sun   +6 more
wiley   +1 more source

Genotoxicity risk assessment of a 7-hydroxymitragynine-enriched Kratom preparation: An integrated in silico and in vitro approach. [PDF]

Toxicol Rep
Harnkit N, Sahad T, Noonate I, Primpai P, Radapong S, Pipatrattanaseree W, Sincharoenpokai P, Chamnanpuen P.   +7 more
europepmc   +1 more source

Backbone double‐mutant cycle analysis quantifies hydrogen‐bond energies in proteins

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Protein structure is stabilized by a variety of noncovalent interactions, but many remain incompletely understood. For example, several potentially ubiquitous interactions involving the protein backbone have been identified, but challenges in determining reliable experimental energies have prevented their integration into structural models. To
Haoliang Zheng, Robert W. Newberry
wiley   +1 more source

Mutagenicity and Repair of Acrolein Adduct to Cytosine. [PDF]

Int J Mol Sci
Dylewska M, Kasperowicz S, Sokołowska B, Maciejewska AM.   +3 more
europepmc   +1 more source

Safety evaluation of pectin-rich extract derived from Coffea arabica as food additive. [PDF]

EFSA J
EFSA Panel on Food Additives and Flavourings (FAF), Castle L, Andreassen M, Aquilina G, Bastos ML, Boon P, Fallico B, FitzGerald R, Frutos Fernandez MJ, Grasl-Kraupp B, Gundert-Remy U, Gürtler R, Houdeau E, Kurek M, Louro H, Morales P, Passamonti S, Barat Baviera JM, Degen G, Gott D, Leblanc JC, Moldeus P, Waalkens-Berendsen I, Wölfle D, Mech A, Tard A, Zakidou P, Ruggeri L.   +27 more
europepmc   +1 more source

Relationship of Dye Adsorption Onto Biomass Activated Carbon Mixed Matrix Ultrafiltration: A Mass Transfer Model Study

Advanced Materials Interfaces, Volume 13, Issue 9, 5 May 2026.
This study explored dye molecule adsorption from water, focusing on activated carbon in polymer membranes for purifying low‐quality water. Polyvinylidene fluoride (PVDF) membranes showed enhanced removal efficiency of methylene blue (MB) from 89.29% to 98.33% with biomass‐activated carbon (BAC).
Khairul Anwar Mohamad Said, Shaiza Asif, Siti Zahara May Abdullah, Ibrahim Yakub, Harunal Rejan Ramji, Md Rezaur Rahman   +5 more
wiley   +1 more source

Genotoxicity assessment of mesoporous silica and graphene oxide in GDL1 cells. [PDF]

Genes Environ
Ishigamori R, Ohno A, Fukuhara K, Hasegawa S, Totsuka Y.   +4 more
europepmc   +1 more source

Engineering a Synthetic Formatotrophic Yeast With Enhanced Growth Capacity on Formate

Advanced Energy and Sustainability Research, Volume 7, Issue 5, May 2026.
Engineering Yeast for Growth on Formate and Methanol via Serine‐Centered C1 Coupling. By engineering serine metabolism and remodeling the rGly pathway, we rendered yeast growth strictly dependent on formate. This synthetic formatotrophy enables growth on dual‐C1 substrates by channeling formate into the central metabolism via serine deaminases and ...
Shuyuan Guo, Gulikezi Maimaitirexiati, Qiannan Zhang, Zhehao Jin, Kaidi Chen, Tiantian Zou, Xuemei Zhao, Xiangjian Liu, Zhenmin Bai, Dashuang Gao, Xudong Kong, Tao Yu   +11 more
wiley   +1 more source