Results 171 to 180 of about 56,155 (258)

Canine Urothelial DNA Mutations Are Not Associated With Total Trihalomethanes Concentrations in Municipal Drinking Water

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Contaminants in municipal drinking water, specifically total trihalomethanes (TTHMs), are mutagenic. Exposures to TTHMs have been associated with urothelial carcinoma (UC) in both people and dogs. Mutations in the BRAF gene and other genomic copy number aberrations detected in voided urothelial cells with commercial CADET BRAF and BRAF‐PLUS ...
Janice O'Brien, Samantha L. Braman, Jennifer Willcox, Phillip Wang, Daniel Gerrity, Audrey Ruple, Lauren A. Trepanier   +6 more
wiley   +1 more source

Editorial: In honor of Dr. Bruce Ames: innovations in mutagenesis and DNA repair. [PDF]

Front Mol Biosci
Giulivi C, Traber MG.
europepmc   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Computational prediction of mutagenicity through comprehensive cell painting analysis. [PDF]

Mutagenesis
Cerisier N, Truong E, Watanabe T, Oshiro T, Takahashi T, Ito S, Taboureau O.   +6 more
europepmc   +1 more source

Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment. [PDF]

Regul Toxicol Pharmacol
Yauk CL, Lynch AM, Dobrovolsky VN, Schuler M, Smith-Roe SL, Fitzgerald D, Higgins J, Honarvar N, Le Curieux F, Matsumura S, Minocherhomji S, Recio L, Salk JJ, Sugiyama KI, Suzuki T, Wills JW, Marchetti F.   +16 more
europepmc   +1 more source

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

International Journal of Cancer, Volume 158, Issue 12, Page 3173-3186, 15 June 2026.
What's new? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte, Hossam Eldesouky, Julia Puchan, Sercan Öz, Elena Everatt, Ashish Goyal, Gianluca Sigismondo, Udo Oppermann, Christoph Plass, Dieter Weichenhan, Ali Bakr   +10 more
wiley   +1 more source

Framework for In Silico Toxicity Screening of Novel Odorants. [PDF]

Toxics
Mohar I, Hansen BC, Hollowed DM, Mainland JD.   +3 more
europepmc   +1 more source

Topological Graph Neural Networks: A Novel Approach for Geometric Deep Learning

Applied AI Letters, Volume 7, Issue 2, June 2026.
This graphical abstract illustrates the Topological Graph Neural Network (TopGNN) architecture. It demonstrates a parallel processing approach where an input graph is simultaneously analyzed by a standard GNN Encoder to capture local node features and by Persistent Homology to extract global topological features (like cycles and voids), visualized as a
Amarjeet, Anurag Sinha, Khalid Hussain, Wasim Ahmad Bhat, Sudhanshu Maurya, Mohammad Nadeem Ahmed, Mohammad Rashid Hussain, S. Khalid   +7 more
wiley   +1 more source

Chemical components of electric vehicle and internal combustion engine vehicle fire smoke and their mutagenic effects. [PDF]

Environ Sci Pollut Res Int
Kim YH, Nored A, Horn GP, Kesler RM, Barowy A, Schraiber A, Gaudet B, Mayer AC, Niemeier-Walsh M, Fent KW, Kovalcik K, Pancras JP, Gilmour MI.   +12 more
europepmc   +1 more source

Electronic Smoking Devices Among University Students: Usage Patterns and Chemical Composition of Inhaled Substances

Analytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT This study investigated the prevalence of electronic smoking device (ESD) use and its associated behavioural and chemical risks among university students in Bahia, Brazil. A cross‐sectional survey was conducted with 355 students from public and private institutions through an online questionnaire between April and May 2023. Among participants,
Eduard F. Valenzuela, Raffael Silva Santos Almeida, Ivana Ferreira Simões, Aline Gonçalves Miranda, Magno Oliveira Ramos, Roberto Rodrigues Bandeira Tosta Maciel, Fernanda Warken Rosa, Aníbal de Freitas Santos Júnior   +7 more
wiley   +1 more source