Results 151 to 160 of about 56,155 (258)

High-Throughput Testing for Unknown Mutagens and Cytotoxica via Duplex Planar Ames-Cytotoxicity Bioassay Including Metabolic S9 Activation. [PDF]

Anal Chem
Schmidtmann K, Kayser AC, Morlock GE.
europepmc   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

SAR Modeling to Predict Ames Mutagenicity Across Different <i>Salmonella typhimurium</i> Strains. [PDF]

Pharmaceuticals (Basel)
Dmitriev AV, Lagunin AA, Rudik AV, Savosina PI, Druzhilovskiy DS, Filimonov DA, Poroikov VV.   +6 more
europepmc   +1 more source

Running an electron microscopy core facility

Journal of Microscopy, EarlyView.
Abstract As electron microscopes became more costly, technically complex, and integral to a wide range of scientific fields, centralised electron microscopy (EM) core facilities have become essential for maintaining accessibility, performance, and quality.
Ilkka Miinalainen, Eija Jokitalo
wiley   +1 more source

Effects of electrochemical ageing of lithium-ion battery electrolyte on its in vitro genotoxicity: a special focus on sultones. [PDF]

Arch Toxicol
Muschiol EC, Tölke LS, Lechtenfeld CT, Kuczius T, Winter M, Nowak S, Esselen M.   +6 more
europepmc   +1 more source

A Comparative Analysis of Maillard‐Derived α‐Dicarbonyl Compounds and Advanced Glycation End Products in Fresh, Wet, Kibble, and Freeze‐Dried Dog Foods

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Thermal processing of pet foods can lead to the formation of harmful Maillard reaction products (MRPs), which may compromise nutritional quality and pose health risks to companion animals. This study compared the levels of MRPs in 41 commercial dog foods, including fresh (n = 15), kibble (n = 13), wet (n = 10), freeze‐dried (n = 2), and cold ...
Tolgahan Kocadağlı, Ciara Clarke, Vural Gökmen   +2 more
wiley   +1 more source

Potential for Computational Genotoxicity: A Report on Symposium 3 of the 53rd Annual Meeting of the Japanese Environmental Mutagen and Genome Society (JEMS), 2024. [PDF]

Genes Environ
Koyama N, Furuhama A, Kruhlak NL, Shinada NK, Izawa K.   +4 more
europepmc   +1 more source

Bacterial Involvement in Oral Squamous Cell Carcinoma and Potentially Malignant Oral Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective To clarify the relationship between oral squamous cell carcinoma (OSCC), potentially malignant oral disease (OPMD), and bacterial flora using metagenomic analysis. Methods This cross‐sectional observational study included 50 patients in the control group and 77 patients with OPMDs, 41 with early OSCCs, and 20 with advanced OSCCs ...
Atsumu Koketsu, Satoshi Fukase, Toru Tamahara, Tatsuru Saito, Akiko Ito, Yutaro Higashi, Tomonari Kajita, Tsuyoshi Kurobane, Masaaki Miyakoshi, Masahiro Iikubo, Kazuki Kumada, Bin Li, Muneaki Shimada, Ritsuko Shimizu, Tetsu Takahashi, Kensuke Yamauchi, Tsuyoshi Sugiura   +16 more
wiley   +1 more source

Evaluation of HSYA and Carthamin Accumulation in Safflower (Carthamus tinctorius L.) Induced by Chemical Mutagens (EMS and SA) in M1 and M2 Generations

Plant Breeding, EarlyView.
ABSTRACT Historically cultivated for medicinal and dyeing purposes, safflower (Carthamus tinctorius L.) saw a shift towards widespread oilseed production after the 1920s due to the growing importance of oils. However, there is a renewed interest in its medicinal and dyeing properties today.
Tansu Uskutoglu, Nurullah Kartaloglu, Belgin Cosge Senkal   +2 more
wiley   +1 more source

Establishment of an Integrated Model for Predicting Compound Mutagenicity with a Feature Importance Analysis. [PDF]

J Chem Inf Model
Yang CH, Lin TE, Hsieh JH, Hsu KC, Chiueh PT.   +4 more
europepmc   +1 more source