Results 141 to 150 of about 35,321 (192)
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Toxicology, 1978
Incubation of Salmonella typhimurium strains in an atmosphere of 0.2% gaseous acrylonitrile increased the numbers of his+ revertants/plate only in the presence of a fortified S9 liver fraction. The mutagenic effect was particularly pronounced with strains TA1530, TA1535 and TA1950 and much weaker with strains TA100, TA98 and TA1978.
C, de Meester +3 more
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Incubation of Salmonella typhimurium strains in an atmosphere of 0.2% gaseous acrylonitrile increased the numbers of his+ revertants/plate only in the presence of a fortified S9 liver fraction. The mutagenic effect was particularly pronounced with strains TA1530, TA1535 and TA1950 and much weaker with strains TA100, TA98 and TA1978.
C, de Meester +3 more
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Mutagenicity of oxytetracycline
Mutation Research/Genetic Toxicology, 1983Oxytetracycline hydrochloride, potassium nitrite and a combination of this antibiotic with the nitrite were tested for their mutagenicity in the host-mediated assay with mice as the host animals. The Salmonella typhimurium strain used was his G46. The bacteria were injected intraperitoneally, and the test compounds were administered by a stomach tube ...
D, Blitek +3 more
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Modulation of mutagenicity by phosphorylation of mutagen-metabolizing enzymes
Archives of Biochemistry and Biophysics, 2004In this Minireview, we discuss our findings on phosphorylation of cytochromes P450 (CYP) and influence of this modification on metabolic toxification and/or detoxification of a variety of mutagens. We show that phosphorylation drastically interferes with the mutagenicity of several classes of compounds which are of high human relevance (cytostatic ...
Barbara, Oesch-Bartlmowicz, Franz, Oesch
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Anti-mutagenicity of catechin against environmental mutagens
Mutagenesis, 1988Catechu is the non-mutagenic component of betel quid. We have tested catechu extract and catechin for anti-mutagenic activity in Salmonella typhimurium strain TA98 against environmental mutagens relevant to India. Catechu extract, as well as catechin, shows a dose-dependent decrease in the mutagenicity of tobacco and masheri extracts, and bidi and ...
M, Nagabhushan, S V, Bhide
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Mutagen and anti-mutagen in ginger, Zingiber officinale
Mutation Research Letters, 1982When rhizome juice of ginger, zingiber officinale, was added to a solution of 2(2-furyl)-3(5-nitro-2-fury)acryl amide (AF2) or N-methyl-N'-nitro-N-nitrosoguanidine (NTG), mutagenesis by these chemicals was markedly increased. As a result of the component fractionation of the ginger juice, it was found that [6]-gingerol was a potent mutagen.
H, Nakamura, T, Yamamoto
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1978
A number of metals are mutagenic in bacteria or phage. These include compounds of arsenic, chromium, copper, iron, manganese, molybdenum, platinum, and selenium. Compounds containing alumium, antimony, arsenic, cadmium, copper, lead, mercury, nickel, and tellium have been shown to induce chromosomal aberrations or abnormal cell divisions in animal or ...
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A number of metals are mutagenic in bacteria or phage. These include compounds of arsenic, chromium, copper, iron, manganese, molybdenum, platinum, and selenium. Compounds containing alumium, antimony, arsenic, cadmium, copper, lead, mercury, nickel, and tellium have been shown to induce chromosomal aberrations or abnormal cell divisions in animal or ...
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Mutation Research/Reviews in Genetic Toxicology, 1975
Seventeen different reports are available dealing with the mutagenic effects of saccharin. Many of these are short abstracts, carrying incomplete information. Mainly tested as its sodium salt, saccharin has been found to be weakly mutagenic in Salmonella at very high doses, in Drosophila at moderate doses, and in mice at moderate to high doses.
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Seventeen different reports are available dealing with the mutagenic effects of saccharin. Many of these are short abstracts, carrying incomplete information. Mainly tested as its sodium salt, saccharin has been found to be weakly mutagenic in Salmonella at very high doses, in Drosophila at moderate doses, and in mice at moderate to high doses.
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Mutation Research/Reviews in Genetic Toxicology, 1990
Verschaeve, Luc, Volders, Micheline
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Verschaeve, Luc, Volders, Micheline
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