Results 91 to 100 of about 31,259 (226)

Assessing Human Ribosomal DNA Variation and Its Association With Phenotypic Outcomes

BioEssays, Volume 47, Issue 4, April 2025.
Genetic variation within the multi‐copy, multi‐locus ribosomal DNA (rDNA) can contribute to human complex trait variability. This variation takes the form of copy number, structural arrangement, and sequence differences. This review summarizes what is currently known about human rDNA variation, its causes, and its association with phenotypic outcomes ...
Francisco Rodriguez‐Algarra, Elliott Whittaker, Sandra del Castillo del Rio, Vardhman K. Rakyan   +3 more
wiley   +1 more source

Mutagens manufactured in fungal culture may affect DNA/RNA of producing fungi

Journal of Applied Microbiology, 2009
Self‐produced mutagens in culture by fungi may affect DNA analysis of the same fungi. This has not been considered previously. Many fungi produce numerous mutagenic secondary metabolites (SM) in culture.
R. Paterson, N. Lima
semanticscholar   +1 more source

Exploring the Utility of Prunus mahaleb Extracts as a Source of Natural Bioactive Compounds for Functional Applications

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
Our findings indicate that P. mahaleb can serve as a versatile raw material for the development of health‐promoting applications, including medicines, cosmeceuticals, and nutraceuticals. ABSTRACT Prunus mahaleb has garnered attention as a potent medicinal agent and functional component.
Bayram Atasagun, Ahmet Uysal, Noha Fathallah, Omayma Eldahshan, Abdel Nasser Singab, Mehmet Veyis Cetiz, Gokhan Zengin   +6 more
wiley   +1 more source

Synthesis, Cytotoxic Activity, Antiquorum Sensing Effect, Docking and Md Simulation of Novel 1,3‐Disubstituted 2‐Mercapto‐1H‐Benzo[D]Imidazolium Chlorides

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 4, April 2025.
A series of benzimidazolium chlorides and their 2‐mercapto were successfully synthesized and characterized. Cytotoxic activity assays revealed that certain synthesized compounds exhibited efficacy against cancer cell lines. To investigate the possible mechanism underlying their cytotoxic effects, the binding interactions of the three most active ...
Mohammad Mavvaji, Muhammed Tilahun Muhammed, Ebru Onem, Halime Güzin Aslan, Sadeq K. Alhag, Senem Akkoc   +5 more
wiley   +1 more source

Radiomimetic beverages, drugs, and mutagens. [PDF]

, 1966
Karl Sax, Hally Jolivette Sax
openalex   +1 more source

Results of awnless brome-grass (Bromopsis inermis Leyss.) breeding in Northern Trans-Ural Region

Аграрная наука Евро-Северо-Востока, 2016
The results are shown of breeding work with awnless brome-grass ( Bromopsis inermis L.) in Northern Zauralye Agricultural Research Institute in 1983-2014.
T. P. Lipovtsyna
doaj  

Thiourea‐Based Compounds Effectiveness Against the Growth of Mycobacterium kansasii: Synthesis, Biological Activity, and Computational Analysis

ChemistrySelect, Volume 10, Issue 16, April 25, 2025.
Fifty thiourea derivatives are synthesized and evaluated against Mycobacterium kansasii. Compounds 2, 47, and 49 demonstrate potent extra‐ and intracellular activity without causing macrophage cytotoxicity, even against the hypervirulent strains. Structure–activity relationships and in silico analyses highlight favorable molecular features and predict ...
Sanderson Dias Calixto, Thatiana Lopes Biá Ventura Simão, Marcos V. Palmeira‐Mello, Gil Mendes Viana, Paloma Wetler Meireles Carreiros Assumpção, Dandara Paiva Barroso de Souza, Camila Couto do Espirito Santo, Vinicius de Oliveira Mussi, Carlos Rangel Rodrigues, Alessandra Mendonça Teles de Souza, Bárbara de A. Abrahim‐Vieira, Lúcio Mendes Cabral, Elena Lasunskaia, Michelle Frazão Muzitano   +13 more
wiley   +1 more source

Flagellar motility is mutagenic

Proceedings of the National Academy of Sciences
Flagella are highly complex rotary molecular machines that enable bacteria to not only migrate to optimal environments but also to promote range expansion, competitiveness, virulence, and antibiotic survival. Flagellar motility is an energy-demanding process, where the sum of its production (biosynthesis) and operation (rotation) costs has
Souvik Bhattacharyya, Shelby Lopez, Abhyudai Singh, Rasika M. Harshey   +3 more
openaire   +3 more sources

Studies on mechanisms for the maintenance of constant mutability: mutability and the resistance to mutagens. [PDF]

, 1966
Stephen Zamenhof, Lilo H. Heldenmuth, Patrice J. Zamenhof   +2 more
openalex   +1 more source

VIABLE MUTANTS INDUCED IN BARLEY BY IONIZING RADIATIONS AND CHEMICAL MUTAGENS

, 2009
Genetic effects of ionizing radiations and chemical mutagens, especially with regard to the induction of viable mutants, were compared in barley.
L. Ehrenberg, A. Gustafsson, U. Lundqvist   +2 more
semanticscholar   +1 more source