Results 91 to 100 of about 43,844 (216)

The Use of the Ames Test as a Tool for Addressing Problem-Based Learning in the Microbiology Lab

Journal of Microbiology & Biology Education, 2012
Our environment is full of potential carcinogens such as UV light, industrial pollutants, pesticides, and food additives, among others. It is estimated that 90% of all carcinogens are also mutagens.
Eliana Rodríguez, Claudia Piccini, Vanessa Sosa, Pablo Zunino   +3 more
doaj   +1 more source

Photodynamic therapy of cancer‐associated infections

Photochemistry and Photobiology, EarlyView.
Pathogens can be involved in tumor initiation, promotion and progression through different mechanisms, and their treatment can prevent new cancer cases, improve outcomes, and revert poor‐prognostic phenotypes. Photodynamic therapy (PDT) successfully treats different types of cancers and infections, and, therefore, has a unique potential to address ...
Giulia Kassab, Juan Chen, Gang Zheng
wiley   +1 more source

Lethal Mutagenesis of Poliovirus Mediated by a Mutagenic Pyrimidine Analogue [PDF]

, 2007
Lethal mutagenesis is the mechanism of action of ribavirin against poliovirus (PV) and numerous other RNA viruses. However, there is still considerable debate regarding the mechanism of action of ribavirin against a variety of RNA viruses.
Brown, Daniel M., Cameron, Craig E., Edathil, Jocelyn P., Franco, David, Graci, Jason D., Harki, Daniel A., Korneeva, Victoria S., Loakes, David, Paul, Aniko V., Peterson, Blake R., Smidansky, Eric D., Too, Kathleen   +11 more
core   +4 more sources

Intergenerational Enlargement of Human Organs as a Driver of Increased Cancer Risk?

BioEssays, Volume 47, Issue 8, August 2025.
Identifying the environmental factors and associated mechanisms driving increased cancer incidence in younger generations is a matter of great urgency. Here, we propose and discuss a new potential mechanism: larger organ sizes in younger individuals resulting from intergenerational differences in lifestyle, diet, and environmental exposures.
Costas Koufaris, Vicky Nicolaidou
wiley   +1 more source

Mutagens affect food and water biodeteriorating fungi [PDF]

, 2015
Many areas of food mycology could be affected detrimentally by mutation of wild type fungi. Some of these will contact mutagens from pre-isolation to experimentation and the effect on fungi isolated from mycotoxin-contaminated food is assessed for ...
Arquiza, Bony, Browne, Callen, Clancy, Filtenborg, Frisvad, Gallo, Grant, Hosoya, Kirk, Kovalchuk, Lamb, Laurence, Martelli, Mayer, Mitchell, Mutwakil, Niggli, Ong, Ong, Opel, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Paterson, Perrone, Pitt, Rath, Ravenna, Rohde, Schmidt-Heydt, Shivanna, Tamame, Wang, Wei, Wilkinson   +40 more
core   +1 more source

Utility of Germline, Somatic and ctDNA Testing in Adults With Cancer

Cancer Medicine, Volume 14, Issue 15, August 2025.
ABSTRACT Background and Aim Historical genetic sequencing of specific cancer variants has been superseded by comprehensive genomic profiling (CGP). This narrative review aimed to capture current international evidence on the clinical utility of CGP for cancer prevention, detection and treatment.
Emily DeBortoli, Ella McGahan, Tatiane Yanes, Jennifer Berkman, Lauren G. Aoude, Amelia K. Smit, Akira Gokoolparsadh, Azure Hermes, Lyndsay Newett, Mackenzie Bourke, Susan Hanson, Helen Hughes, Oliver Hofmann, Ilias Goranitis, Rebekah McWhirter, Vivienne Milch, Julia Steinberg, Aideen McInerney‐Leo   +17 more
wiley   +1 more source

Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells

Journal of Applied Toxicology, Volume 45, Issue 8, Page 1555-1571, August 2025.
ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal, Melanie Coughlan, Andrée Nunnikhoven, Reena Corbane, Cathy Cummings‐Lorbetskie, Andrea Rowan‐Carroll, Tanvi Sharma, Andrew Williams, Jessie R. Lavoie, Andrew Stalker, Asish Mohapatra, Matthew J. Meier   +11 more
wiley   +1 more source

Allergenicity, Genotoxicity and Subchronic Toxicity Assessment of IgG Binding Protein LT Produced From Aspergillus oryzae

Journal of Applied Toxicology, Volume 45, Issue 8, Page 1614-1636, August 2025.
ABSTRACT Gastrointestinal health is one of the fastest growing areas in the food and beverage industry, as its importance to overall health and well‐being is becoming increasingly recognized. Immunoglobulins play a key role in protecting the gastrointestinal tract, and nonbovine sources of immunoglobulins (including camel milk, which has a long history
Kirt R. Phipps, Sachin Patel, Kevin Scaife, Toby Holmes, Alica Šoltésová, Sandra Wingaard Thrane, Louise Kristine Vigsnæs, Nigel Baldwin, Christel Jørgensen   +8 more
wiley   +1 more source

Химические мутагены в селекции цветочно-декоративных растений [PDF]

, 2006
Results of the effect of diethylsulfate (DES), dimethylsulfate (DMS), nitrosoethilcarbamide (NEC), nitrosomethylcarbomide (NMC) on seeds and vegetative organs of flower-ornamental plants are considered. Suppressive action of the NMC and NEC studied doses
Кудина, Г.А.
core  

Results of awnless brome-grass (Bromopsis inermis Leyss.) breeding in Northern Trans-Ural Region

Аграрная наука Евро-Северо-Востока, 2016
The results are shown of breeding work with awnless brome-grass ( Bromopsis inermis L.) in Northern Zauralye Agricultural Research Institute in 1983-2014.
T. P. Lipovtsyna
doaj