Results 71 to 80 of about 44,639 (231)

Antimutagenic effect of ellagic acid and its effect on the immune response in mice

open access: yesCzech Journal of Food Sciences, 2002
Using the Ames bacterial mutagenicity test and an in vivo micronucleus test, we investigated the antigenotoxic effect of ellagic acid on the genotoxicity of three mutagens: amino-methylimidazo-quinoline (IQ), aflatoxin B1 (AFB1), and N-nitroso-N ...
P. Šmerák   +7 more
doaj   +1 more source

RAGE Re‐Expressed at Myofibre Level Drives Muscle Wasting in Cancer Conditions

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Cancer cachexia (CC) is a highly debilitating syndrome characterized by loss of body and muscle weight affecting most advanced cancer patients. The receptor for advanced glycation end‐products (RAGE) is expressed by several cell types and sustains the inflammatory response in acute and chronic diseases. Total ablation of RAGE (Ager−/
Sara Chiappalupi   +10 more
wiley   +1 more source

Defining Solvent and Concentration Type to Maximise Polyphenol Extraction and Antioxidant Activity in Rubia cordifolia L. and Taraxacum officinale Weber

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Comparative extraction of bioactive polyphenols and antioxidant activities from different plant parts of Rubia cordifolia and Taraxacum officinale using different solvent systems. ABSTRACT This investigation aims to determine the most suitable solvent system and concentration for extracting different polyphenols and the antioxidant activity from ...
Deepti Tiwari   +4 more
wiley   +1 more source

An organometallic compound which exhibits a DNA topology-dependent one-stranded intercalation mode [PDF]

open access: yes, 2016
Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions.
Adhireksan   +16 more
core   +3 more sources

Antimutagenic effect of resveratrol

open access: yesCzech Journal of Food Sciences, 2005
Evidence exists from population-based and laboratory studies that some phytochemicals have protective effects against tumors or other diseases and reveal antimutagenic activity.
Martina Langová   +4 more
doaj   +1 more source

Quercetin elevates p27Kip1 and arrests both primary and HPV16 E6/E7 transformed human keratinocytes in G1 [PDF]

open access: yes, 2003
Our previous work with primary bovine fibroblasts demonstrated that quercetin, a potent mutagen found in high levels in bracken fern (Pteridium aquilinum), arrested cells in G1 and G2/M, in correlation with p53 activation.
Alan G. Casson   +30 more
core   +1 more source

A comparison of the effects of physical and chemical mutagens in sesame (Sesamum indicum L.)

open access: yesGenetics and Molecular Biology, 2010
Three sesame genotypes (Rama, SI 1666 and IC 21706) were treated with physical (γ-rays: 200 Gy, 400 Gy or 600 Gy) or chemical (ethyl methane sulphonate, EMS: 0.5%, 1.0%, 1.5% or 2.0%) mutagens and their mutagenic effectiveness and efficiency were ...
Tamina Begum, Tapash Dasgupta
doaj  

Antimutagenic effect of curcumin and its effect on the immune response in mice

open access: yesCzech Journal of Food Sciences, 2006
A wide array of antioxidative and anti-inflammatory substances derived from edible plants have been reported to possess chemopreventive and chemoprotective activities.
Petr Šmerák   +7 more
doaj   +1 more source

Oxytocin‐ und Vasopressin‐Photosonden zur Entschlüsselung der Neuropeptid‐Signalgebung mit hoher räumlicher und zeitlicher Präzision

open access: yesAngewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Neue biokompatible Oxytocin‐ und Vasopressin‐Photosonden mit modernsten Photocages. Diese Photosonden sind inaktiv und können mit spezifischen Lichtwellen entschützt werden, was eine Rezeptoraktivierung mit hoher zeitlicher und räumlicher Kontrolle ermöglicht. Abbildung erstellt mit https://BioRender.com ZUSAMMENFASSUNG Das Oxytocin/Vasopressin (OT/VP)
Konstantin Raabe   +7 more
wiley   +1 more source

Heterogeneous reactions of particulate matter-bound PAHs and NPAHs with NO3/N2O5, OH radicals, and O3 under simulated long-range atmospheric transport conditions: reactivity and mutagenicity. [PDF]

open access: yes, 2014
The heterogeneous reactions of ambient particulate matter (PM)-bound polycyclic aromatic hydrocarbons (PAHs) and nitro-PAHs (NPAHs) with NO3/N2O5, OH radicals, and O3 were studied in a laboratory photochemical chamber. Ambient PM2.5 and PM10 samples were
Arey, Janet   +8 more
core   +2 more sources

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