Results 51 to 60 of about 19,596 (187)
In-Host Flat-like Quasispecies: Characterization Methods and Clinical Implications
The repeated failure to treat patients chronically infected with hepatitis E (HEV) and C (HCV) viruses, despite the absence of resistance-associated substitutions (RAS), particularly in response to prolonged treatments with the mutagenic agents of HEV ...
Josep Gregori +17 more
doaj +1 more source
Meiotic changes in Vicia faba L. subsequent to treatments of hydrazine hydrate and maleic hydrazide [PDF]
Assessing the impact of mutagens for creating variations in crops like faba bean (Vicia faba L.) is an important criterion in the contemporary world where food insecurity and malnutrition is alarming at the doors of various nations.
Shaheen Husain +3 more
doaj
ABSTRACT This review provides a critical overview of research on fully bio‐based benzoxazines over the period 2015–2025. A bibliometric analysis based on the Web of Science database is used to map how the field has evolved and to identify the renewable building blocks that have been most widely adopted.
Elizabeth Alvarez Perez, Alice Mija
wiley +1 more source
Mutagenic effectiveness and efficiency are the most important factors determining the success of mutation breeding, a coherent tool for quickly enhancing diversity in crops.
Anas Hamisu +4 more
doaj +1 more source
Maize Biofortification Approaches for Fighting Malnutrition in Sub‐Saharan Africa
ABSTRACT Maize is a staple food in sub‐Saharan Africa (SSA); however, commonly used maize varieties are deficient in essential nutrients, including lysine, tryptophan, vitamin A, and minerals such as iron (Fe) and zinc (Zn). As a result, millions of people in this region suffer from one or more nutrient deficiencies that commonly lead to malnutrition ...
Bitew Tilahun Engida +2 more
wiley +1 more source
Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha ( Withania somnifera )
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan +2 more
wiley +1 more source
Antimutagenic effect of ellagic acid and its effect on the immune response in mice
Using the Ames bacterial mutagenicity test and an in vivo micronucleus test, we investigated the antigenotoxic effect of ellagic acid on the genotoxicity of three mutagens: amino-methylimidazo-quinoline (IQ), aflatoxin B1 (AFB1), and N-nitroso-N ...
P. Šmerák +7 more
doaj +1 more source
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
ABSTRACT To safeguard global food security against rapid population growth and a warming world, the effective genetic improvement of cereals is imperative. Flower opening time (FOT) critically affects the seed setting rate. In this study, we identified a gene, EARLY‐MORNING FLOWERING 3 (EMF3), in which single‐nucleotide substitutions strongly modulate ...
Takuma Ishizaki +18 more
wiley +1 more source
Antimutagenic effect of resveratrol
Evidence exists from population-based and laboratory studies that some phytochemicals have protective effects against tumors or other diseases and reveal antimutagenic activity.
Martina Langová +4 more
doaj +1 more source

