Results 51 to 60 of about 44,639 (231)
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto +7 more
wiley +1 more source
Redressing the Silent Interim: Precautionary Action & Short Term Tests in Toxicological Risk Assessment [PDF]
The author recommends that a stronger emphasis be placed on creating and implementing short-term tests that use iterative, conservative-based, tiered procedures in conjunction with a precautionary attitude during the interim phase of toxicological risk ...
Riley, Timothy
core +1 more source
His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]
The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M. +3 more
core +1 more source
Study of the antimutagenic effects of plant polyphenols under the action of genotoxicants
In the test of dominant lethal germ cell mutations in male rats, the effect of phenobarbital and fluorouracil genotoxicants and their combined administration with the biotrit-C preparation, obtained from wheat seedlings and containing plant polyphenols ...
V. S. Ivanov
doaj
INDUCTION OF CHLOROPHYLL MUTANTS IN COMMON BEAN UNDER THE ACTION OF CHEMICAL MUTAGENS ENU AND EMS [PDF]
Effect of treatment with different concentrations of N-nitroso-N-ethyl urea (ENU) and etylmethan sulfonate (ЕМS) on seeds of Bulgarian common bean Dobroudjanski 7, Dobroudjanski 2, Plovdiv 10, Plovdiv 11М and snap bean Tcher Starozagorski varieties, for ...
Diana Lilova SVETLEVA
doaj
Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan +2 more
wiley +1 more source
FEATURES OF DETERMINING MASS EMISSIONS OF PARTICULATE MATTER IN DIESEL ENGINES EXHAUST GASES [PDF]
The paper deals with the problems of features of experimental comparative research of particulate filters of performance for diesel engines in general, and experimental and estimated determination of mass emissions of particulate matter as one of the ...
O. Kondratenko, O. Strokov, S. Vambol’
doaj
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
The Importance of DNA Repair in Tumor Suppression
The transition from a normal to cancerous cell requires a number of highly specific mutations that affect cell cycle regulation, apoptosis, differentiation, and many other cell functions.
B. Vogelstein +8 more
core +1 more source
Induced mutations in cowpea, Vigna unguiculata (Leguminosae)
Two cowpea (Vigna unguiculata L. Walp) varieties, IT84E-124 and Vita 7 of the International Institute of Tropical Agriculture, Ibadan, were exposed to varying doses of chemical and physical mutagens.
P.G.C. Odeigah +2 more
doaj

