Results 61 to 70 of about 26,211 (229)

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source

Carcinogens, Mutagens, Reproductive Toxicants

, 2009
Nous avons le plaisir de vous annoncer la tenue d'une conférence internationale intitulée : « Carcinogens, Mutagens, Reproductive Toxicants: the Politics of Limit Values and Low Doses in the twentieth and twenty-first centuries ».

core   +1 more source

Transcriptomic Analysis Reveals Core Genes and Mechanisms Linking Grilled Food Toxicants (4‐HNE, BaP, PhIP) to NASH‐HCC Progression

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
This study identifies a six‐gene signature (GSTA1, EPHX1, CYP2E1, GPX3, ALB, TF) that mediates how grilled food toxicants (4‐HNE, BaP, PhIP) synergistically drive NASH‐to‐HCC progression via oxidative stress, metabolic dysfunction, and immune microenvironment remodeling, providing a robust diagnostic nomogram for early risk stratification.
Bingbing Qin, Ye Zhang, Na Li, Jing Li, Yuehua Luo, Xi Tang, Ruisheng Zhou, Tianqi Cui, Ying Tang   +8 more
wiley   +1 more source

Effect of physical and chemical mutagens on soybean [PDF]

, 2011
Two varieties of soybean (Glycine max (L) Merill) viz., JS-335 and PKV-1 were treated with various doses of physical (gamma rays) and chemical (EMS) mutagens. A dose dependent decrease was noticed in most of the characters like plant survival germination.
Wakode2, Geeta P. Patil1 and Manish M.
core  

Anti-mutagenic agents are also co-recombinogenic and can be converted into co-mutagens

, 2022
S.59-67In experiments using yeast without an external metabolic activation system, the hormones testosterone, beta-estradiol and diethylstilbistrol were anti-mutagenic and co-recombinogenic. In the presence of Aroclor-induced rat liver S-9 plus cofactors
Fahrig, R.
core   +1 more source

Meat Intake and Risk of Gastric and Esophageal Adenocarcinoma in the European Prospective Investigation Into Cancer and Nutrition (EPIC) Study

International Journal of Cancer, Volume 159, Issue 5, Page 1176-1187, 1 September 2026.
Limited evidence links processed meat intake and non‐cardia gastric cancer, while esophageal adenocarcinoma is increasing in Western countries, where diets are typically high in red and processed meats. Using data from over 450,000 participants from a large prospective study, the authors examined meat consumption and the risk of gastric and esophageal ...
Catalina Bonet, Lucía Rizzolo‐Brime, Sara Montañés, Mariem Hajji, Chloé Marques, Gianluca Severi, Matthias B Schulze, Christina C. Dahm, Anne Tjønneland, Anja Olsen, Maria S. De Magistris, Valeria Pala, Alberto Catalano, Guri Skeie, Magritt Brustad, Torill Enget Jensen, Maria‐José Sánchez, Marcela Guevara, Natalia Cabrera Castro, Keren Papier, Elisabete Weiderpass, Viktoria Knaze, Jin Young Park, Gwen Murphy, Antonio Agudo, Paula Jakszyn   +25 more
wiley   +1 more source

Seed viability, germination and seedling growth of canola (Brassica napus L.) as influenced by chemical mutagens [PDF]

, 2013
Mutation induction is considered as an effective way to enrich plant genetic variation, particularly for traits with a very low level of genetic variation. The objectives of this study were to evaluate the effect of different dosages of chemical mutagens
Emrani, SN, Arzani, A, Saeidi, G
core   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

International Journal of Cancer, Volume 159, Issue 5, Page 1311-1321, 1 September 2026.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn, Rachel Lawrence, Hasan Haboubi, Hamsa Naser, Kate Hurlow, Ume‐Kulsoom Shah, Lisa Williams, Sarah Gwynne, Owen Bodger, Jiri Zavadil, Francois Virard, Shareen Doak, Laura E. Thomas, Gareth Jenkins   +13 more
wiley   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

Comprehensive Investigation of Benzimidazolium Derivatives Through Synthesis, Characterization, Cytotoxicity Activity, Immunocytochemistry, and ADME and Toxicity Analyses

ChemistryOpen, Volume 15, Issue 9, September 2026.
Three benzimidazolium derivatives bearing fluoro, chloro, and methoxy substituents are synthesized and evaluated for anticancer activity. Compound 2b shows the highest antiproliferative activity and induces apoptosis through caspase‐3 activation and PARP1 cleavage. In this study, three novel benzimidazolium derivatives (2a–c) bearing 4‐fluoro, 3‐chloro,
Gulay Dilek, Senem Akkoc
wiley   +1 more source