Results 121 to 130 of about 53,897 (283)

A mathematical model of DNA degradation: Possible role of magnetic nanoparticles [PDF]

open access: yesarXiv, 2007
A mathematical model of genome degradation is proposed that takes into account a variable rate of mutation and increasing number of cells in a developing human organism. The model explains known properties of cancer development, in particular, a synergism between different mutagens and an increased probability of cancer in the early years of life.
arxiv  

Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

open access: yesBritish Journal of Cancer, 2009
Background:Epidemiological evidence on meat intake and breast cancer is inconsistent, with little research on potentially carcinogenic meat-related exposures.
Leah M. Ferrucci   +9 more
semanticscholar   +1 more source

A comparison of the effects of physical and chemical mutagens in sesame (Sesamum indicum L.)

open access: yesGenetics and Molecular Biology, 2010
Three sesame genotypes (Rama, SI 1666 and IC 21706) were treated with physical (γ-rays: 200 Gy, 400 Gy or 600 Gy) or chemical (ethyl methane sulphonate, EMS: 0.5%, 1.0%, 1.5% or 2.0%) mutagens and their mutagenic effectiveness and efficiency were ...
Tamina Begum, Tapash Dasgupta
doaj  

The Use of the Ames Test as a Tool for Addressing Problem-Based Learning in the Microbiology Lab

open access: yesJournal of Microbiology & Biology Education, 2012
Our environment is full of potential carcinogens such as UV light, industrial pollutants, pesticides, and food additives, among others. It is estimated that 90% of all carcinogens are also mutagens.
Eliana Rodríguez   +3 more
doaj   +1 more source

Exploring the Utility of Prunus mahaleb Extracts as a Source of Natural Bioactive Compounds for Functional Applications

open access: yesFood Science &Nutrition, Volume 13, Issue 4, April 2025.
Our findings indicate that P. mahaleb can serve as a versatile raw material for the development of health‐promoting applications, including medicines, cosmeceuticals, and nutraceuticals. ABSTRACT Prunus mahaleb has garnered attention as a potent medicinal agent and functional component.
Bayram Atasagun   +6 more
wiley   +1 more source

Synthesis, Cytotoxic Activity, Antiquorum Sensing Effect, Docking and Md Simulation of Novel 1,3‐Disubstituted 2‐Mercapto‐1H‐Benzo[D]Imidazolium Chlorides

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 39, Issue 4, April 2025.
A series of benzimidazolium chlorides and their 2‐mercapto were successfully synthesized and characterized. Cytotoxic activity assays revealed that certain synthesized compounds exhibited efficacy against cancer cell lines. To investigate the possible mechanism underlying their cytotoxic effects, the binding interactions of the three most active ...
Mohammad Mavvaji   +5 more
wiley   +1 more source

DNA Copy Number Variations as Markers of Mutagenic Impact [PDF]

open access: yes, 2019
DNA copy number variation (CNV) occurs due to deletion or duplication of DNA segments resulting in a different number of copies of a specific DNA-stretch on homologous chromosomes.
Aroutiounian, Rouben   +3 more
core   +1 more source

Micronucleus induction by 915 MHz Radiofrequency Radiation in Vicia faba root tips [PDF]

open access: yesarXiv, 2014
The mutagenic effect of radiofrequency electromagnetic field (RF-EMF) is evaluated by the micronucleus (MN) test in secondary roots of Vicia faba seedlings. Root exposures were carried out with 915 MHz continuous wave (CW) radiation for 72h, at power densities of 25, 38, 50 W/m$^2$.
arxiv  

Mitochondrial Complex I Molecular Alterations in Sapajus apella as a Human Gastric Carcinogenesis Model After MNU Exposure

open access: yesJournal of Medical Primatology, Volume 54, Issue 2, April 2025.
ABSTRACT Introduction Gastric cancer (GC) remains among the top five global health problems. Therefore, comprehending the tumor energetic behavior is critical to understanding its progression. This study aimed to investigate mitochondrial DNA (mtDNA) alterations in GC cancer cell lines in an animal model.
Bárbara dos Santos Dias   +4 more
wiley   +1 more source

Dynamics and bifurcations in a simple quasispecies model of tumorigenesis [PDF]

open access: yesarXiv, 2014
Cancer is a complex disease and thus is complicated to model. However, simple models that describe the main processes involved in tumoral dynamics, e.g., competition and mutation, can give us clues about cancer behaviour, at least qualitatively, also allowing us to make predictions.
arxiv  

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