Results 31 to 40 of about 49,008 (223)
Carcinogenic and mutagenic agents in the workplace, Poland, 2011–2012
Medycyna Pracy, 2015 Background: The objective of the study was the analysis of structure of carcinogenic or mutagenic chemical substances and dusts occurring in Polish enterprises, 2011–2012, including the number of exposed employees reported to the “Central register of ...
Anna Pałaszewska-Tkacz +2 more
doaj +1 more source
Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.
Proceedings of the National Academy of Sciences of the United States of America, 1975 We described previously a simple test on petri plates for detecting chemical carcinogens as mutagens, using an especially sensitive set of bacterial strains to detect mutagenic acitivty and a mammalian liver extract for carcinogen activity. We now extend
J. McCann +3 more
semanticscholar +1 more source
Effect of induced mutagenesis in M1 and M2 generations of cumin (Cuminum cyminum L.)
Electronic Journal of Plant Breeding, 2023 Cumin is an important spice that has been used for centuries in various cuisines around the world. Two cumin varieties (GC 3 and GC 4) were subjected to mutation to understand macromutational modifications.
H. N. Patel1*, M. P. Patel2, N. V. Soni1, N. B. Patel1, A. M. Patel3 and N. I. Patel4
doaj +1 more source
HARMLESS Early Warning System for Advanced Materials
Advanced Sustainable Systems, EarlyView.The HARMLESS Early Warning System tackles Advanced Materials (AdMa) risk governance by providing a framework, organised in two tiers, underpinned with methods/tools to support risk assessors in the pre‐assessment preceding risk assessment. It allows for initial screening to identify AdMa with concerns considering exposure, hazards, sustainability and ...
Julia Prinz +11 more
wiley +1 more source
In-Host Flat-like Quasispecies: Characterization Methods and Clinical Implications
MicroorganismsThe repeated failure to treat patients chronically infected with hepatitis E (HEV) and C (HCV) viruses, despite the absence of resistance-associated substitutions (RAS), particularly in response to prolonged treatments with the mutagenic agents of HEV ...
Josep Gregori +17 more
doaj +1 more source
Ecological and genetic assessment of the consequences of radiation influence on contaminated areas
Вавиловский журнал генетики и селекции, 2020 The objects of study are the territory of the districts of the West Kazakhstan region of the Republic of Kazakhstan adjacent to the Kapustin Yar test site: Bokeyordinsky, Zhangalinsky, Zhanibeksky, Kaztalovsky, Akzhayiksky and Syrymsky.
A. B. Bigaliev +7 more
doaj +1 more source
Advanced Science, EarlyView.This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang +8 more
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1982 A new tester strain, TA102, is described as an addition to the set of strains for the Salmonella/microsome mutagenicity test. This strain contains A X T base pairs at the site of the mutation (determined by DNA sequence analysis) in contrast to the other
D. E. Levin +4 more
semanticscholar +1 more source
Dietary meat mutagens intake and cancer risk: A systematic review and meta-analysis
Frontiers in Nutrition, 2022 BackgroundClinical and preclinical studies suggested that certain mutagens occurring as a reaction of creatine, amino acids, and sugar during the high temperature of cooking meat are involved in the pathogenesis of human cancer.
Qie Reng +6 more
doaj +1 more source
Angewandte Chemie International Edition, Accepted Article.Mitochondrial DNA (mtDNA) encodes essential genes for mitochondrial and cellular functions and acts as a cell signaling molecule in innate immune and inflammatory responses. Defects in mtDNA are implicated in a range of mitochondrial disorders and human diseases. Currently, no chemical strategy exists to prevent mtDNA loss under genotoxic stress.
Anal Jana, Yu-Hsuan Chen, Linlin Zhao
wiley +1 more source