Results 41 to 50 of about 25,742 (173)

FEATURES OF DETERMINING MASS EMISSIONS OF PARTICULATE MATTER IN DIESEL ENGINES EXHAUST GASES [PDF]

Avtomobilʹnyj Transport (Harʹkov), 2014
The paper deals with the problems of features of experimental comparative research of particulate filters of performance for diesel engines in general, and experimental and estimated determination of mass emissions of particulate matter as one of the ...
O. Kondratenko, O. Strokov, S. Vambol’
doaj  

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl, J. Christopher Corton, Henghong Li, Jiri Aubrecht, Scott S. Auerbach, Florian Caiment, Tatyana Y. Doktorova, Yurika Fujita, Danyel Jennen, Naoki Koyama, Matthew J. Meier, Roman Mezencev, Leslie Recio, Takayoshi Suzuki, Carole L. Yauk   +14 more
wiley   +1 more source

In-Host Flat-like Quasispecies: Characterization Methods and Clinical Implications

Microorganisms
The repeated failure to treat patients chronically infected with hepatitis E (HEV) and C (HCV) viruses, despite the absence of resistance-associated substitutions (RAS), particularly in response to prolonged treatments with the mutagenic agents of HEV ...
Josep Gregori, Sergi Colomer-Castell, Marta Ibañez-Lligoña, Damir Garcia-Cehic, Carolina Campos, Maria Buti, Mar Riveiro-Barciela, Cristina Andrés, Maria Piñana, Alejandra González-Sánchez, Francisco Rodriguez-Frias, Maria Francesca Cortese, David Tabernero, Ariadna Rando-Segura, Tomás Pumarola, Juan Ignacio Esteban, Andrés Antón, Josep Quer   +17 more
doaj   +1 more source

Meiotic changes in Vicia faba L. subsequent to treatments of hydrazine hydrate and maleic hydrazide [PDF]

Journal of BioScience and Biotechnology, 2013
Assessing the impact of mutagens for creating variations in crops like faba bean (Vicia faba L.) is an important criterion in the contemporary world where food insecurity and malnutrition is alarming at the doors of various nations.
Shaheen Husain, Mohammad Imran Kozgar, Iram Fatma Jafrey, Samiullah Khan   +3 more
doaj  

Antimutagenic effect of ellagic acid and its effect on the immune response in mice

Czech Journal of Food Sciences, 2002
Using the Ames bacterial mutagenicity test and an in vivo micronucleus test, we investigated the antigenotoxic effect of ellagic acid on the genotoxicity of three mutagens: amino-methylimidazo-quinoline (IQ), aflatoxin B1 (AFB1), and N-nitroso-N ...
P. Šmerák, H. Šestáková, Z. Polívková, I. Bárta, B. Turek, J. Bártová, M. Langová, M. Anděl   +7 more
doaj   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

Antimutagenic effect of curcumin and its effect on the immune response in mice

Czech Journal of Food Sciences, 2006
A wide array of antioxidative and anti-inflammatory substances derived from edible plants have been reported to possess chemopreventive and chemoprotective activities.
Petr Šmerák, Zdeňka Polívková, Helena Šestáková, Rudolf Štětina, Ivo Bárta, Martina Langová, Bohumil Turek, Jiřina Bártová   +7 more
doaj   +1 more source

An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract

Journal of Applied Toxicology, EarlyView.
ABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
J. Kyle Weston, Barry S. Lynch, James A. Akingbasote   +2 more
wiley   +1 more source

Antimutagenic effect of resveratrol

Czech Journal of Food Sciences, 2005
Evidence exists from population-based and laboratory studies that some phytochemicals have protective effects against tumors or other diseases and reveal antimutagenic activity.
Martina Langová, Zdeňka Polívková, Petr Šmerák, Jiřina Bártová, Ivo Bárta   +4 more
doaj   +1 more source