Results 41 to 50 of about 73,569 (303)

Adapting the Interrelated Two-way Clustering method for Quantitative Structure-Activity Relationship (QSAR) Modeling of a Diverse Set of Chemical Compounds

, 2013
Interrelated Two-way Clustering (ITC) is an unsupervised clustering method developed to divide samples into two groups in gene expression data obtained through microarrays, selecting important genes simultaneously in the process.
Basak, Subhash C., Grunwald, Gregory D., Majumdar, Subhabrata   +2 more
core   +1 more source

Mechanisms linking colorectal cancer to the consumption of (processed) red meat : a review [PDF]

, 2015
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The vast majority of CRC cases have been linked to environmental causes rather than to heritable genetic changes.
De Smet, Stefaan, Demeyer, Daniël, Mertens, Birgit, Ulens, Michèle   +3 more
core   +2 more sources

Meiotic changes in Vicia faba L. subsequent to treatments of hydrazine hydrate and maleic hydrazide [PDF]

Journal of BioScience and Biotechnology, 2013
Assessing the impact of mutagens for creating variations in crops like faba bean (Vicia faba L.) is an important criterion in the contemporary world where food insecurity and malnutrition is alarming at the doors of various nations.
Shaheen Husain, Mohammad Imran Kozgar, Iram Fatma Jafrey, Samiullah Khan   +3 more
doaj  

In-Host Flat-like Quasispecies: Characterization Methods and Clinical Implications

Microorganisms
The repeated failure to treat patients chronically infected with hepatitis E (HEV) and C (HCV) viruses, despite the absence of resistance-associated substitutions (RAS), particularly in response to prolonged treatments with the mutagenic agents of HEV ...
Josep Gregori, Sergi Colomer-Castell, Marta Ibañez-Lligoña, Damir Garcia-Cehic, Carolina Campos, Maria Buti, Mar Riveiro-Barciela, Cristina Andrés, Maria Piñana, Alejandra González-Sánchez, Francisco Rodriguez-Frias, Maria Francesca Cortese, David Tabernero, Ariadna Rando-Segura, Tomás Pumarola, Juan Ignacio Esteban, Andrés Antón, Josep Quer   +17 more
doaj   +1 more source

Ecological and genetic assessment of the consequences of radiation influence on contaminated areas

Вавиловский журнал генетики и селекции, 2020
The objects of study are the territory of the districts of the West Kazakhstan region of the Republic of Kazakhstan adjacent to the Kapustin Yar test site: Bokeyordinsky, Zhangalinsky, Zhanibeksky, Kaztalovsky, Akzhayiksky and Syrymsky.
A. B. Bigaliev, K. Z. Shalabaeva, B. E. Shimshikov, S. S. Kobegenova, L. M. Adilova, A. N. Kozhakhmetova, S. Sharakhmetov, M. N. Burkhanova   +7 more
doaj   +1 more source

Biochemical mutagens affect the preservation of fungi and biodiversity estimations [PDF]

, 2013
Many fungi have significant industrial applications or biosafety concerns and maintaining the original characteristics is essential. The preserved fungi have to represent the situation in nature for posterity, biodiversity estimations, and taxonomic ...
A Bubak, A Martelli, A Wiest, D Smith, DGI Mitchell, DL Hawksworth, H Mori, H Oh, H Pellanda, IM Santos, J Dupont, J-K Liu, JC Frisvad, JJ Wong, JR Wilkinson, KF Nielsen, LF Bjeldanes, LG Kammoun, M Marin-Kuan, M Wiebe, ME Stack, MJ Ryan, MP Singh, MR Andersen, Nelson Lima, O Sterner, R. Russell M. Paterson, RJ Cole, RRM Paterson, RRM Paterson, RRM Paterson, RRM Paterson, RRM Paterson, RRM Paterson, S Bony, SB Krasnoff, SC Fleck, TA Mobio, TJ Schrader, Z Herceg   +39 more
core   +1 more source

Mussel eggs as indicators of mutagen exposure in coastal and estuarine environments [PDF]

, 1994
The aim of this study was to develop a short-term genotoxicity assay for monitoring the marine environment for mutagens. Based on the developing eggs and embryos of the marine mussel Mytilus edulis, an important pollution indicator species, the test ...
Dixon, D.R., Pascoe, P.L
core  

Evaluation of the genotoxic and teratogenic potential of a municipal sludge and sludge-amended soil using the amphibian Xenopus laevis and the tobacco: Nicotiana tabacum L. var. xanthi Dulieu [PDF]

, 2003
The toxic, genotoxic and teratogenicpotential of amunicipal sewage sludge was assessed using the micronucleus assay on the larvae of the amphibianXenopuslaevis and with the tobacco somatic mutation test using the yellow–green xanthiDulieu mutant a1+/a1 ...
Chenon, Pascale, Delpoux, Marcel, Gauthier, Laury, Loubières, Pascale, Séverac, Alain   +4 more
core   +2 more sources

HARMLESS Early Warning System for Advanced Materials

Advanced Sustainable Systems, EarlyView.
The HARMLESS Early Warning System tackles Advanced Materials (AdMa) risk governance by providing a framework, organised in two tiers, underpinned with methods/tools to support risk assessors in the pre‐assessment preceding risk assessment. It allows for initial screening to identify AdMa with concerns considering exposure, hazards, sustainability and ...
Julia Prinz, Gregor Nagel, Susan Dekkers, Eugene P. van Someren, Véronique Adam, Veronica Di Battista, Blanca Suarez‐Merino, Wendel Wohlleben, Michael Persson, Anders Baun, Otmar Schmid, Andrea Haase   +11 more
wiley   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source