Results 41 to 50 of about 49,008 (223)

Enhanced Production of Astaxanthin and Zeaxanthin by Paracoccus Sp. LL1 Through Random Mutagenesis

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Astaxanthin, a high‐value carotenoid with potent antioxidant and anti‐inflammatory activities, is increasingly in demand in various industries. This study reports the successful enhancement of astaxanthin and zeaxanthin production in Paracoccus sp. LL1 through random mutagenesis using ethyl methanesulfonate (EMS).
Anoth Maharjan, Beom Soo Kim
wiley   +1 more source

Antimutagenic effect of ellagic acid and its effect on the immune response in mice

open access: yesCzech Journal of Food Sciences, 2002
Using the Ames bacterial mutagenicity test and an in vivo micronucleus test, we investigated the antigenotoxic effect of ellagic acid on the genotoxicity of three mutagens: amino-methylimidazo-quinoline (IQ), aflatoxin B1 (AFB1), and N-nitroso-N ...
P. Šmerák   +7 more
doaj   +1 more source

Intergenerational Enlargement of Human Organs as a Driver of Increased Cancer Risk?

open access: yesBioEssays, EarlyView.
Identifying the environmental factors and associated mechanisms driving increased cancer incidence in younger generations is a matter of great urgency. Here, we propose and discuss a new potential mechanism: larger organ sizes in younger individuals resulting from intergenerational differences in lifestyle, diet, and environmental exposures.
Costas Koufaris, Vicky Nicolaidou
wiley   +1 more source

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1976
About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test.
J. McCann, B. Ames
semanticscholar   +1 more source

Cell mutagens

open access: yesCalifornia Agriculture, 1982
Not available – first paragraph follows: Realizing the full potential of plant somatic cell genetic techniques will depend on development of methods for isolating a wide variety of cultured cell strains with characteristics different from those of cells
G Jones
doaj  

Antimutagenic effect of curcumin and its effect on the immune response in mice

open access: yesCzech Journal of Food Sciences, 2006
A wide array of antioxidative and anti-inflammatory substances derived from edible plants have been reported to possess chemopreventive and chemoprotective activities.
Petr Šmerák   +7 more
doaj   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal   +14 more
wiley   +1 more source

Meat-cooking mutagens and risk of renal cell carcinoma

open access: yesBritish Journal of Cancer, 2011
Background:High-temperature cooked meat contains two families of carcinogens, heterocyclic amines (HCAs) and polycyclic aromatic hydrocarbons (PAHs). Given the kidneys’ role in metabolism and urinary excretion of these compounds, we investigated meat ...
C. Daniel   +12 more
semanticscholar   +1 more source

EFFECT OF ETHYL METHANESULFONATE (EMS) AND N-NITROSE-N´-ETHYL UREA (ENU) ON CALLUS GROWTH OF COMMON BEAN [PDF]

open access: yesJournal of Central European Agriculture, 2005
Infl uence of ethyl methanesulfonate (EMS) and N-nitrose-N´-ethyl urea (ENU) mutagenic treatments was investigated on three time sub-cultured calli obtained from leaf petiole explants of 7-day old sterile plants.
Diana Lilova SVETLEVA, Paola CRINÓ
doaj  

Antimutagenic effect of resveratrol

open access: yesCzech Journal of Food Sciences, 2005
Evidence exists from population-based and laboratory studies that some phytochemicals have protective effects against tumors or other diseases and reveal antimutagenic activity.
Martina Langová   +4 more
doaj   +1 more source

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