Results 101 to 110 of about 2,159,893 (336)

Targeting Oncogenic BRAF: Past, Present, and Future. [PDF]

, 2019
Identifying recurrent somatic genetic alterations of, and dependency on, the kinase BRAF has enabled a "precision medicine" paradigm to diagnose and treat BRAF-driven tumors.
Bivona, Trever G, Wu, Wei, Zaman, Aubhishek   +2 more
core   +1 more source

Phytochrome mutants [PDF]

The Plant Journal, 1991
Kendrick, R.E., Nagatani, A.
openaire   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Comparative Transcriptomic Analysis of Gossypium hirsutum Fiber Development in Mutant Materials (xin w 139) Provides New Insights into Cotton Fiber Development

Plants
Cotton is the most widely planted fiber crop in the world, and improving cotton fiber quality has long been a research hotspot. The development of cotton fibers is a complex process that includes four consecutive and overlapping stages, and although many
Chunping Li, Jieyin Zhao, Zhongshan Liu, Yanlong Yang, Chengxia Lai, Jun Ma, Alifu Aierxi   +6 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Genetic, molecular and expression features of the Pervenets mutant leading to high oleic acid content of seed oil in sunflower

Oléagineux, Corps gras, Lipides, 2002
Pervenets is a sunflower population that displays seed oil with a high oleic acid content [HOAC]. Our aim is to reconcile all the data gathered on this mutant in a unique explanatory mechanism.
Lacombe Séverine, Leger Sandrine, Kaan François, Berville André, Sas Monsanto   +4 more
doaj   +1 more source

Mutations in troABCD against Copper Overload in a copA Mutant of Streptococcus suis

, 2022
Yang Xia, Wei Peng, Yanna Wang, Kang Yan, Zewen Liu, Ting Gao, Keli Yang, Wei Liu, Rui Guo, Chang Li, Huanchun Chen, Yongxiang Tian, Danna Zhou, Weicheng Bei, Fangyan Yuan   +14 more
openalex   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Assessment of drought tolerance in Nagina 22 mutants of rice using Poly Ethylene Glycol (PEG)

Electronic Journal of Plant Breeding, 2020
A laboratory experiment was conducted to screen 500 EMS induced mutants of Nagina22 using low molecular osmotic PEG-6000. The analysis of variance showed that all ten characters showed significant variation at 1% probability level.
K. Manonmani, P. Jeyaprakash, S. Manonmani, M. Raveendran and P. Jeyakumar
doaj   +1 more source

Thymidine mutants [PDF]

Journal of Clinical Pathology, 1978
R, Maskell, O A, Okubadejo
openaire   +2 more sources