Results 101 to 110 of about 2,913,254 (384)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Molecular and genetic dissection of peduncle elongation in rice [PDF]

Electronic Journal of Plant Breeding, 2011
Incomplete panicle exsertion in almost all the WA-based CMS lines is one of the major impediments in obtaining higher seedyield in hybrid rice breeding programs.
A. Subathra Devi , V.Krishnasamy, M.Raveendran, N.Senthil and S.Manonmani
doaj  

Turnip Mosaic Virus Coat Protein Deletion Mutants Allow Defining Dispensable Protein Domains for ‘in Planta’ eVLP Formation

Viruses, 2020
The involvement of different structural domains of the coat protein (CP) of turnip mosaic virus, a potyvirus, in establishing and/or maintaining particle assembly was analyzed through deletion mutants of the protein.
Carmen Yuste-Calvo, Pablo Ibort, Flora Sánchez, Fernando Ponz   +3 more
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Unique Regulation of Sed-1 β-Lactamase in Citrobacter sedlakii: Insights on Resistance to Third-Generation Cephalosporin

Antibiotics
Background: The Citrobacter genus harbors class C (AmpC) and class A β-lactamases. Citrobacter freundii produces an inducible AmpC β-lactamase controlled by the LysR-type transcriptional regulator AmpR and cytosolic amidase AmpD.
Mako Watanabe, Ryuichi Nakano, Keizo Yamamoto, Akiyo Nakano, Yuki Suzuki, Kai Saito, Satoko Nakashima, Kentaro Endo, Kazuya Narita, Hisakazu Yano   +9 more
doaj   +1 more source

The improvement of early maturity red rice mutant trait for drought tolerance

International Journal of Plant Biology, 2017
Accession of red rice does not have the traits of early maturity, drought tolerance and high yield. Mutation is needed to obtain the desired genetic resources.
Eries D. Mustikarini, Noer Rahmi Ardiarini, Nur Basuki, Kuswanto Kuswanto   +3 more
doaj   +1 more source

Letter to the editor: autoimmune pathogenic mechanisms in amyotrophic lateral sclerosis [PDF]

, 2018
The innate immune system may affect the function and survival of motor neurons in ALS by at least three mechanisms. First, there is evidence to suggest that aggregates of mutant SOD1—which is derived from microglial and astroglial cells—activate ...
de Vincentiis, M., De Virgilio, A., Gallo, A., Greco, A., Inghilleri, M., Ralli, M.   +5 more
core   +1 more source

KRAS-Mutant non-small cell lung cancer: From biology to therapy.

Lung Cancer, 2018
In patients with non-small cell lung cancer (NSCLC), the most frequent oncogene driver mutation in Western countries is Kirsten rat sarcoma viral oncogene homolog (KRAS), and KRAS-mutant NSCLC is associated with smoking.
I. Ferrer, J. Zugazagoitia, S. Herbertz, W. John, L. Paz-Ares, G. Schmid‐Bindert   +5 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source