Results 181 to 190 of about 2,088,899 (353)
Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
THE CONSEQUENCES OF MUTATION DURING THE GROWTH OF BIOCHEMICAL MUTANTS OF ESCHERICHIA COLI III [PDF]
, 1949 Francis J. Ryan, Lillian K. Schneider
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
THE INDUCED FORMATION OF NITRATE REDUCTASE IN AUXOTROPHIC MUTANTS OF ESCHERICHIA COLI [PDF]
, 1956 S. D. Wainwright, Ann Nevill
openalex +1 more source
Acta Scientiarum Polonorum: Hortorum Cultus, 2014 To optimize the protocol, the shoot tips of Chrysanthemum × grandiflorum (Ramat.) Kitam. radiomutants have been cryopreserved using the encapsulationdehydration technique, following different approaches. In the experiment the influence of abscisic acid –
Małgorzata Zalewska, Dariusz Kulus
doaj
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Production and Testing of Yeast Mutants for Glycerol Formation1 [PDF]
, 1957 R. E. Wright +2 more
openalex +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Mutant Isoalleles at the Vermilion Locus in Drosophila Melanogaster
, 1952 M. M. Green
openalex +1 more source