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Fundamentals and emerging frontiers in p53-targeted drug development. [PDF]
Biochem Biophys RepLong HD +16 more
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Polyphosphate synthesis is essential for phosphate and ATP homeostasis during nutrient upshift. [PDF]
Proc Natl Acad Sci U S AWhite ML +11 more
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Cuproptosis inducers mediate cold lethality via SLCR-46.1 in C. elegans. [PDF]
Nat CommunYamashiro S +7 more
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Reducing Mutants with Mutant Killable Precondition
2017 IEEE International Conference on Software Testing, Verification and Validation Workshops (ICSTW), 2017Mutation analysis is a method for predicting the quality of test suite accurately. However, it has high computational cost due to the number of mutants that are generated. For example, the ROR (Relational Operator Replacement) mutation operator will generate seven mutants for just one relational operator.
Chihiro Iida, Shingo Takada 0001
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29th International Conference on Software Engineering (ICSE'07 Companion), 2007
Mutation is the practice of automatically generating possibly faulty variants of a program, for the purpose of assessing the adequacy of a test suite or comparing testing techniques. The cost of mutation often makes its application infeasible. The cost of mutation is usually assessed in terms of the number of mutants, and consequently the number of ...
Akbar Siami Namin, James H. Andrews
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Mutation is the practice of automatically generating possibly faulty variants of a program, for the purpose of assessing the adequacy of a test suite or comparing testing techniques. The cost of mutation often makes its application infeasible. The cost of mutation is usually assessed in terms of the number of mutants, and consequently the number of ...
Akbar Siami Namin, James H. Andrews
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Nature, 1988
Nucleic acids are replicated with conspicuous fidelity. Infrequently, however, they undergo changes in sequence, and this process of change (mutation) generates the variability that allows evolution. As the result of studies of bacterial variation, it is now widely believed that mutations arise continuously and without any consideration for their ...
J, Cairns, J, Overbaugh, S, Miller
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Nucleic acids are replicated with conspicuous fidelity. Infrequently, however, they undergo changes in sequence, and this process of change (mutation) generates the variability that allows evolution. As the result of studies of bacterial variation, it is now widely believed that mutations arise continuously and without any consideration for their ...
J, Cairns, J, Overbaugh, S, Miller
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Genetica, 1995
This paper provides an analytic treatment of the effect of differential fitness of mutants and non-mutants on the Luria-Delbruck distribution, which is used to describe the number of mutant cells obtained prior to selection during a fluctuation test experiment.
Gregg Jaeger, Sahotra Sarkar
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This paper provides an analytic treatment of the effect of differential fitness of mutants and non-mutants on the Luria-Delbruck distribution, which is used to describe the number of mutant cells obtained prior to selection during a fluctuation test experiment.
Gregg Jaeger, Sahotra Sarkar
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Canadian Journal of Biochemistry and Cell Biology, 1985
Genetics has become an important tool for studying microtubule structure and function. Mutations in genes that encode microtubule proteins have been isolated in several, evolutionarily diverse organisms. These mutations have been, and will increasingly be, of great value in determining which cellular events are microtubule mediated, in determining ...
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Genetics has become an important tool for studying microtubule structure and function. Mutations in genes that encode microtubule proteins have been isolated in several, evolutionarily diverse organisms. These mutations have been, and will increasingly be, of great value in determining which cellular events are microtubule mediated, in determining ...
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