Results 81 to 90 of about 2,114,568 (336)
Deletion mutants of bacteriophage phiX174 [PDF]
, 1972 Mutants of bacteriophage phiX174 have been isolated that are less dense than wild-type phiX particles in CsCl. When mutant viral (+) strand DNA and wild-type complementary (-) strand DNA are hybridized, the resulting duplex molecules have single-stranded
Benbow, Robert M. +2 more
core
Empirical Evaluation of Mutation-based Test Prioritization Techniques
, 2018 We propose a new test case prioritization technique that combines both mutation-based and diversity-based approaches. Our diversity-aware mutation-based technique relies on the notion of mutant distinguishment, which aims to distinguish one mutant's ...
Bae, Doo-Hwan +3 more
core +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Exit of Plasmodium Sporozoites from Oocysts Is an Active Process That Involves the Circumsporozoite Protein [PDF]
, 2005 Plasmodium sporozoites develop within oocysts residing in the mosquito midgut. Mature sporozoites exit the oocysts, enter the hemolymph, and invade the salivary glands.
Fujioka, Hisashi +2 more
core +4 more sources
Mitigating the effects of equivalent mutants with mutant classification strategies [PDF]
Science of Computer Programming, 2014 Mutation Testing has been shown to be a powerful technique in detecting software faults. Despite this advantage, in practice there is a need to deal with the equivalent mutants' problem. Automatically detecting equivalent mutants is an undecidable problem.
Papadakis, Mike +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
The improvement of early maturity red rice mutant trait for drought tolerance
International Journal of Plant Biology, 2017 Accession of red rice does not have the traits of early maturity, drought tolerance and high yield. Mutation is needed to obtain the desired genetic resources.
Eries D. Mustikarini +3 more
doaj +1 more source
Temperature and mutant expression [PDF]
Experientia, 1961 Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire +2 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 Herein, we report the effect of nine FDA approved protease inhibitor drugs against a new HIV-1 subtype C mutant protease, E35D↑G↑S. The mutant has five mutations, E35D, two insertions, position 36 (G and S), and D60E.
Sibusiso Maseko +9 more
doaj +1 more source