Results 81 to 90 of about 1,846,603 (258)
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Problem on Mutant Pairs of Hyperbolic Polyhedra [PDF]
arXiv, 2019 We present a notion of mutation of hyperbolic polyhedra, analogous to mutation in knot theory, and then present a general question about commensurability of mutant pairs of polyhedra. We motivate that question with several concrete examples of mutant pairs for which commensurability is unknown.
arxiv
THE PROPORTION OF MUTANTS IN BACTERIAL CULTURES [PDF]
, 1957 John H. Northrop, M. Kunitz
openalex +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
A Haploid Mutant in the Jimson Weed, " Datura stramonium " [PDF]
, 1922 A. F. Blakeslee +3 more
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Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
Molecular Oncology, EarlyView.Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler +12 more
wiley +1 more source
A computational systems biology study of the lambda-lac mutants [PDF]
arXiv, 2007 We present a comprehensive computational study of some 900 possible "lambda-lac" mutants of the lysogeny maintenance switch in phage lambda, of which up to date 19 have been studied experimentally (Atsumi & Little, PNAS 103: 4558-4563, (2006)). We clarify that these mutants realise regulatory schemes quite different from wild-type lambda, and can ...
arxiv
A Mutant of Drosophila Melanogaster Resembling the So-Called Unstable Genes of Drosophila Virilis [PDF]
, 1943 Richard Goldschmidt
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Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
EVIDENCE FROM TETRAD ANALYSIS FOR BOTH NORMAL AND ABERRANT RECOMBINATION BETWEEN ALLELIC MUTANTS IN Neurospora Crassa [PDF]
, 1958 Mary E. Case, Norman H. Giles
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