Results 251 to 260 of about 4,355,944 (375)

Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS).

Nucleic Acids Research, 1989
C. Newton, A. Graham, L. Heptinstall, S. Powell, C. Summers, N. Kalsheker, J. Smith, A. Markham   +7 more
semanticscholar   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Genomic landscape of <i>Mycobacterium tuberculosis</i>: Identifying mutation hotspots and stable regions for implications for drug development. [PDF]

New Microbes New Infect
Khan MT, Luo Z, Al Khatib AO, Alshaya DS, Al-Qahtani AA, Nadeem T.   +5 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Efficacy and prognostic analysis of chemo-immunotherapy after TKI resistance in EGFR-mutant non-small cell lung cancer with TP53 or KRAS co-mutations. [PDF]

Front Immunol
Nie Y, Song C, Wu K, Yu M, Hu J, Liu S, Hui F.   +6 more
europepmc   +1 more source

A single homozygous point mutation in a 3′untranslated region motif of selenoprotein N mRNA causes SEPN1‐related myopathy [PDF]

, 2006
Valérie Allamand, Pascale Richard, Alain Lescure, C. Ledeuil, Delphine Desjardin, Nathalie Petit, Corine Gartioux, Ana Ferreiro, Alain Krol, N. Pellegrini, Jon Andoni Urtizberea, Pascale Guicheney   +11 more
openalex   +1 more source

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

Science, 2014
E. Tran, S. Turcotte, A. Gros, P. Robbins, Yong-Chen Lu, M. Dudley, J. Wunderlich, R. Somerville, Katherine A. Hogan, C. Hinrichs, M. Parkhurst, J. Yang, S. Rosenberg   +12 more
semanticscholar   +1 more source

APC mutations [PDF]

Nature, 1992
openaire   +2 more sources

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Next-Generation Sequencing Reveals a Diagnostic and Prognostic Role of the <i>TP53</i> R273C Mutation in Lower-Grade, <i>IDH</i>-Mutant Astrocytomas. [PDF]

Int J Mol Sci
Navarro L, Megías J, Salazar-Saura I, Sánchez-Pardo M, Roselló-Sastre E, San-Miguel T.   +5 more
europepmc   +1 more source