Results 261 to 270 of about 2,716,384 (302)
Some of the next articles are maybe not open access.
Journal of Theoretical Biology, 2003
A traditional picture of evolutionary dynamics with constant fitness is that of genomes living in sequence space and adapting on fitness landscapes. Mutation rates are considered to be constant or externally regulated. If, however, we take into account that genomes also encode for enzymes that perform replication and error correction, then individual ...
Sasaki, Akira, Nowak, Martin A.
openaire +2 more sources
A traditional picture of evolutionary dynamics with constant fitness is that of genomes living in sequence space and adapting on fitness landscapes. Mutation rates are considered to be constant or externally regulated. If, however, we take into account that genomes also encode for enzymes that perform replication and error correction, then individual ...
Sasaki, Akira, Nowak, Martin A.
openaire +2 more sources
1978
With the exception of repair mutagenesis, which was reviewed two years ago (RHEASE, 3), the investigations of the basic molecular mechanisms of mutation induction by chemical substances seem to have reached a certain saturation level. The different types of mutations like transitions, transversions, deletions, frameshift mutations, backbone breakage ...
openaire +1 more source
With the exception of repair mutagenesis, which was reviewed two years ago (RHEASE, 3), the investigations of the basic molecular mechanisms of mutation induction by chemical substances seem to have reached a certain saturation level. The different types of mutations like transitions, transversions, deletions, frameshift mutations, backbone breakage ...
openaire +1 more source
Mutational analysis: new mutations
1995Abstract In the last few years the search for mutations and sequence polymorphisms has been dramatically accelerated by the use of PCR and subsequently by direct sequencing of PCR products (1, 2). In spite of these powerful new methods, direct sequencing is not always practicable in detecting mutations because they may be positioned ...
K Michaelides +4 more
openaire +1 more source
Mutational analysis: known mutations
1995Abstract This chapter attempts to illustrate the various PCR options that are available to detect specific mutations and/or polymorphisms in genomic DNA. In so doing, the relative merits and drawbacks of each technique are addressed in the respective sections. For some methods of PCR-assisted mutation detection covered in this chapter, a
openaire +1 more source
Evolution of the germline mutation rate across vertebrates
Nature, 2023Lucie A Bergeron +2 more
exaly
Mutation bias reflects natural selection in Arabidopsis thaliana
Nature, 2022J Grey Monroe +2 more
exaly