Results 271 to 280 of about 1,816,562 (311)
Some of the next articles are maybe not open access.
1978
With the exception of repair mutagenesis, which was reviewed two years ago (RHEASE, 3), the investigations of the basic molecular mechanisms of mutation induction by chemical substances seem to have reached a certain saturation level. The different types of mutations like transitions, transversions, deletions, frameshift mutations, backbone breakage ...
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With the exception of repair mutagenesis, which was reviewed two years ago (RHEASE, 3), the investigations of the basic molecular mechanisms of mutation induction by chemical substances seem to have reached a certain saturation level. The different types of mutations like transitions, transversions, deletions, frameshift mutations, backbone breakage ...
openaire +1 more source
Dermatologic Clinics, 2010
A mutation is an event that produces heritable changes in the DNA. There are many different types of mutations, including point mutations (changes that imply loss, duplication, or alterations of small DNA segments, often involving a single or a few nucleotides) and major DNA changes (loss, duplication, or rearrangements of entire genes or of gene ...
Daniele, Castiglia, Giovanna, Zambruno
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A mutation is an event that produces heritable changes in the DNA. There are many different types of mutations, including point mutations (changes that imply loss, duplication, or alterations of small DNA segments, often involving a single or a few nucleotides) and major DNA changes (loss, duplication, or rearrangements of entire genes or of gene ...
Daniele, Castiglia, Giovanna, Zambruno
openaire +2 more sources
Mutational analysis: new mutations
1995Abstract In the last few years the search for mutations and sequence polymorphisms has been dramatically accelerated by the use of PCR and subsequently by direct sequencing of PCR products (1, 2). In spite of these powerful new methods, direct sequencing is not always practicable in detecting mutations because they may be positioned ...
K Michaelides +4 more
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Hospital Practice, 1985
The recent revolution in our understanding of biochemical genetics has radically altered the simple concepts that held sway “only yesterday.” Correspondingly, our appreciation of the complexity and variety of mutation has begun to provide a biochemical rationale for much of the clinical heterogeneity observed in many genetic diseases—e.g., the beta ...
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The recent revolution in our understanding of biochemical genetics has radically altered the simple concepts that held sway “only yesterday.” Correspondingly, our appreciation of the complexity and variety of mutation has begun to provide a biochemical rationale for much of the clinical heterogeneity observed in many genetic diseases—e.g., the beta ...
openaire +2 more sources
Mutational analysis: known mutations
1995Abstract This chapter attempts to illustrate the various PCR options that are available to detect specific mutations and/or polymorphisms in genomic DNA. In so doing, the relative merits and drawbacks of each technique are addressed in the respective sections. For some methods of PCR-assisted mutation detection covered in this chapter, a
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Evolution of the germline mutation rate across vertebrates
Nature, 2023Lucie A Bergeron +2 more
exaly
Mutation bias reflects natural selection in Arabidopsis thaliana
Nature, 2022J Grey Monroe +2 more
exaly